vortioxetine Gene Set

Dataset	Guide to Pharmacology Chemical Ligands of Receptors
Category	physical interactions
Type	ligand (chemical)
Description	An N-arylpiperazine in which the aryl group is specified as 2-[(2,4-dimethylphenyl)sulfanyl]phenyl. Used (as its hydrobromide salt) for treatment of major depressive disorder. (Chemical Entities of Biological Interest Ontology, CHEBI_76016)
External Link	http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=7351
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Genes

9 receptors of the vortioxetine ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Symbol	Name
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR5A	5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTR7	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
SLC6A4	solute carrier family 6 (neurotransmitter transporter), member 4