vacuolar protein sorting 35 homolog (S. cerevisiae)|This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 55737)
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6 genes co-occuring with the biological term vps35 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
