vwf Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Is a quantification of von Willebrand factor (vWF) is a blood glycoprotein involved in hemostasis. It is deficient or defective in von Willebrand disease and is involved in a large number of other diseases, including thrombotic thrombocytopenic purpura, Heyde's syndrome, and possibly hemolytic-uremic syndrome.[1] Increased plasma levels in a large number of cardiovascular, neoplastic, and connective tissue diseases are presumed to arise from adverse changes to the endothelium, and may contribute to an increased risk of thrombosis. (Experimental Factor Ontology, EFO_0004629)
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Genes

77 genes co-occuring with the biological term vwf in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACE angiotensin I converting enzyme
ADAM28 ADAM metallopeptidase domain 28
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ANO2 anoctamin 2, calcium activated chloride channel
ANXA2 annexin A2
APOH apolipoprotein H (beta-2-glycoprotein I)
AQP2 aquaporin 2 (collecting duct)
AVPR2 arginine vasopressin receptor 2
CD36 CD36 molecule (thrombospondin receptor)
CDH5 cadherin 5, type 2 (vascular endothelium)
CFH complement factor H
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EDN1 endothelin 1
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FGA fibrinogen alpha chain
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP5 glycoprotein V (platelet)
GP6 glycoprotein VI (platelet)
GP9 glycoprotein IX (platelet)
GZMM granzyme M (lymphocyte met-ase 1)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICAM1 intercellular adhesion molecule 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LAMB1 laminin, beta 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
MAPK8 mitogen-activated protein kinase 8
MCAM melanoma cell adhesion molecule
MYO5A myosin VA (heavy chain 12, myoxin)
MYRIP myosin VIIA and Rab interacting protein
NOS3 nitric oxide synthase 3 (endothelial cell)
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PECAM1 platelet/endothelial cell adhesion molecule 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAT plasminogen activator, tissue
PLCG1 phospholipase C, gamma 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROCR protein C receptor, endothelial
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RAB27A RAB27A, member RAS oncogene family
S100A10 S100 calcium binding protein A10
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SH3GL2 SH3-domain GRB2-like 2
STX2 syntaxin 2
STXBP5 syntaxin binding protein 5 (tomosyn)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
THBD thrombomodulin
THBS1 thrombospondin 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNNT1 troponin T type 1 (skeletal, slow)
UTS2 urotensin 2
VCAM1 vascular cell adhesion molecule 1
VIM vimentin
VWA1 von Willebrand factor A domain containing 1
VWA2 von Willebrand factor A domain containing 2
VWF von Willebrand factor
YY1 YY1 transcription factor