waist circumference Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The measurement around the body at the level of the ABDOMEN and just above the hip bone. The measurement is usually taken immediately after exhalation. (Experimental Factor Ontology, EFO_0004342)
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Genes

148 genes associated with the disease waist circumference in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACOT11 acyl-CoA thioesterase 11
AGBL1 ATP/GTP binding protein-like 1
AMBP alpha-1-microglobulin/bikunin precursor
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANO3 anoctamin 3
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BBX bobby sox homolog (Drosophila)
BCCIP BRCA2 and CDKN1A interacting protein
BCDIN3D BCDIN3 domain containing
C10ORF105 chromosome 10 open reading frame 105
C11ORF24 chromosome 11 open reading frame 24
C6ORF106 chromosome 6 open reading frame 106
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CAMTA1 calmodulin binding transcription activator 1
CCDC169 coiled-coil domain containing 169
CCDC88C coiled-coil domain containing 88C
CCND3 cyclin D3
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDH13 cadherin 13
CDH23 cadherin-related 23
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHN2 chimerin 2
COL4A1 collagen, type IV, alpha 1
CSMD3 CUB and Sushi multiple domains 3
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTSD cathepsin D
CUBN cubilin (intrinsic factor-cobalamin receptor)
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CYFIP1 cytoplasmic FMR1 interacting protein 1
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DLG2 discs, large homolog 2 (Drosophila)
DNAH10 dynein, axonemal, heavy chain 10
DPT dermatopontin
ECT2L epithelial cell transforming 2 like
EDIL3 EGF-like repeats and discoidin I-like domains 3
EPAS1 endothelial PAS domain protein 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
EVA1A eva-1 homolog A (C. elegans)
FAIM2 Fas apoptotic inhibitory molecule 2
FAM13A family with sequence similarity 13, member A
FAM155A family with sequence similarity 155, member A
FAM177A1 family with sequence similarity 177, member A1
FAM178A family with sequence similarity 178, member A
FAM69C family with sequence similarity 69, member C
FANK1 fibronectin type III and ankyrin repeat domains 1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FHIT fragile histidine triad
FTO fat mass and obesity associated
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GRIK4 glutamate receptor, ionotropic, kainate 4
HAS3 hyaluronan synthase 3
HDAC9 histone deacetylase 9
IL1RAP interleukin 1 receptor accessory protein
IL6 interleukin 6
IPCEF1 interaction protein for cytohesin exchange factors 1
IRG1 immunoresponsive 1 homolog (mouse)
KALRN kalirin, RhoGEF kinase
KANK4 KN motif and ankyrin repeat domains 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KIAA1614 KIAA1614
KIF26A kinesin family member 26A
KLF12 Kruppel-like factor 12
KLHL36 kelch-like family member 36
KRI1 KRI1 homolog (S. cerevisiae)
KSR2 kinase suppressor of ras 2
L2HGDH L-2-hydroxyglutarate dehydrogenase
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LHFP lipoma HMGIC fusion partner
LIN28B lin-28 homolog B (C. elegans)
LMO7 LIM domain 7
LPAR1 lysophosphatidic acid receptor 1
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MC4R melanocortin 4 receptor
MED27 mediator complex subunit 27
MEIS2 Meis homeobox 2
MYO18B myosin XVIIIB
NEB nebulin
NKAIN2 Na+/K+ transporting ATPase interacting 2
NPAS3 neuronal PAS domain protein 3
NRG1 neuregulin 1
NRXN3 neurexin 3
NUP85 nucleoporin 85kDa
OPRM1 opioid receptor, mu 1
OR51I2 olfactory receptor, family 51, subfamily I, member 2
OR7G1 olfactory receptor, family 7, subfamily G, member 1
OVCH2 ovochymase 2 (gene/pseudogene)
PACRG PARK2 co-regulated
PAX7 paired box 7
PCDH7 protocadherin 7
PCP4 Purkinje cell protein 4
PFKP phosphofructokinase, platelet
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PPARG peroxisome proliferator-activated receptor gamma
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PTPRG protein tyrosine phosphatase, receptor type, G
RBBP5 retinoblastoma binding protein 5
RBM47 RNA binding motif protein 47
RGS6 regulator of G-protein signaling 6
RNF215 ring finger protein 215
RYR2 ryanodine receptor 2 (cardiac)
SAMD4A sterile alpha motif domain containing 4A
SARDH sarcosine dehydrogenase
SCHIP1 schwannomin interacting protein 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC39A12 solute carrier family 39 (zinc transporter), member 12
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SMYD3 SET and MYND domain containing 3
SNX25 sorting nexin 25
SORCS2 sortilin-related VPS10 domain containing receptor 2
SOS2 son of sevenless homolog 2 (Drosophila)
SP110 SP110 nuclear body protein
SP140 SP140 nuclear body protein
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPIDR scaffolding protein involved in DNA repair
SRPK2 SRSF protein kinase 2
STON1 stonin 1
STON1-GTF2A1L STON1-GTF2A1L readthrough
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUMO3 small ubiquitin-like modifier 3
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TENM4 teneurin transmembrane protein 4
TGIF1 TGFB-induced factor homeobox 1
TKT transketolase
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE4 transducin-like enhancer of split 4
TOB1 transducer of ERBB2, 1
TPH2 tryptophan hydroxylase 2
TSPAN11 tetraspanin 11
UBASH3B ubiquitin associated and SH3 domain containing B
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UHRF1BP1 UHRF1 binding protein 1
UMOD uromodulin
ZFAT zinc finger and AT hook domain containing
ZFHX3 zinc finger homeobox 3