werner syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [LS]. (Human Disease Ontology, DOID_5688)
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Genes

155 genes co-occuring with the disease werner syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
WRN Werner syndrome, RecQ helicase-like 4.21581
RECQL4 RecQ protein-like 4 2.04191
RECQL RecQ helicase-like 1.98993
RECQL5 RecQ protein-like 5 1.9066
BLM Bloom syndrome, RecQ helicase-like 1.80292
WRNIP1 Werner helicase interacting protein 1 1.55468
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 1.41665
LMNA lamin A/C 1.40745
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.31013
FEN1 flap structure-specific endonuclease 1 1.29964
PURG purine-rich element binding protein G 1.25037
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.24863
RAD18 RAD18 E3 ubiquitin protein ligase 1.23082
TOP3A topoisomerase (DNA) III alpha 1.17636
RAD52 RAD52 homolog (S. cerevisiae) 1.11898
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 1.11015
DNA2 DNA replication helicase/nuclease 2 1.10763
H2AFX H2A histone family, member X 1.10343
PLRG1 pleiotropic regulator 1 1.06312
TOP1 topoisomerase (DNA) I 1.02144
ATM ATM serine/threonine kinase 1.01934
RAD51 RAD51 recombinase 1.01554
DNAH8 dynein, axonemal, heavy chain 8 0.996549
POT1 protection of telomeres 1 0.988957
NHEJ1 nonhomologous end-joining factor 1 0.97128
NEIL1 nei endonuclease VIII-like 1 (E. coli) 0.946186
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.946186
PARP1 poly (ADP-ribose) polymerase 1 0.917611
RAD54L RAD54-like (S. cerevisiae) 0.878195
ERCC6 excision repair cross-complementation group 6 0.866321
LYPD1 LY6/PLAUR domain containing 1 0.851992
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.835198
TP53 tumor protein p53 0.831099
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.830689
DDX11L8 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 8 0.830689
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.796642
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.794181
RPA2 replication protein A2, 32kDa 0.771252
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.769618
MUS81 MUS81 structure-specific endonuclease subunit 0.761047
RALY RALY heterogeneous nuclear ribonucleoprotein 0.754934
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.754527
BCAS2 breast carcinoma amplified sequence 2 0.748017
PCNA proliferating cell nuclear antigen 0.74436
LIG4 ligase IV, DNA, ATP-dependent 0.72329
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.719654
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 0.714408
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.711183
ANK1 ankyrin 1, erythrocytic 0.703938
MAPK14 mitogen-activated protein kinase 14 0.699919
NUP107 nucleoporin 107kDa 0.696306
RAD50 RAD50 homolog (S. cerevisiae) 0.684692
PARP2 poly (ADP-ribose) polymerase 2 0.683093
ERCC2 excision repair cross-complementation group 2 0.680697
SIRT7 sirtuin 7 0.678701
ERCC4 excision repair cross-complementation group 4 0.678302
GOLGA3 golgin A3 0.672324
NDC1 NDC1 transmembrane nucleoporin 0.666755
SIRT1 sirtuin 1 0.663975
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.660404
PRPF19 pre-mRNA processing factor 19 0.639463
SIRT6 sirtuin 6 0.638282
UNG uracil-DNA glycosylase 0.62728
RPA1 replication protein A1, 70kDa 0.615921
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 0.608494
SAFB scaffold attachment factor B 0.57655
RPS9 ribosomal protein S9 0.563723
SSRP1 structure specific recognition protein 1 0.561392
RAD54B RAD54 homolog B (S. cerevisiae) 0.553239
RBPMS RNA binding protein with multiple splicing 0.549747
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.549359
EXO1 exonuclease 1 0.545868
INS insulin 0.545868
CDK20 cyclin-dependent kinase 20 0.530768
CDC5L cell division cycle 5-like 0.518805
SSBP1 single-stranded DNA binding protein 1, mitochondrial 0.514956
SIRT2 sirtuin 2 0.510344
SNHG12 small nucleolar RNA host gene 12 0.505739
GSR glutathione reductase 0.498467
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.493885
BRCA1 breast cancer 1, early onset 0.493885
PML promyelocytic leukemia 0.485505
TERT telomerase reverse transcriptase 0.482464
SIRT5 sirtuin 5 0.482084
SIRT4 sirtuin 4 0.481325
SLC7A4 solute carrier family 7, member 4 0.476772
RPS3 ribosomal protein S3 0.476772
TREX1 three prime repair exonuclease 1 0.475255
TAGLN transgelin 0.457109
NEFL neurofilament, light polypeptide 0.456732
POLM polymerase (DNA directed), mu 0.449947
FGFR1 fibroblast growth factor receptor 1 0.446182
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.446182
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.433021
INSR insulin receptor 0.426265
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.407919
CIDEC cell death-inducing DFFA-like effector c 0.399707
RMI1 RecQ mediated genome instability 1 0.396725
ERCC1 excision repair cross-complementation group 1 0.384451
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.384451
VCP valosin containing protein 0.383708
RFC3 replication factor C (activator 1) 3, 38kDa 0.370737
LMNB1 lamin B1 0.370368
SIRT3 sirtuin 3 0.369628
FANCD2 Fanconi anemia, complementation group D2 0.36187
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.348981
RFC4 replication factor C (activator 1) 4, 37kDa 0.338707
MLH1 mutL homolog 1 0.337975
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.328469
IGFBP3 insulin-like growth factor binding protein 3 0.328105
UBE2N ubiquitin-conjugating enzyme E2N 0.325552
CHEK1 checkpoint kinase 1 0.318635
FN1 fibronectin 1 0.316456
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.315003
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.314278
RAD17 RAD17 homolog (S. pombe) 0.313189
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.303059
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.299812
HAT1 histone acetyltransferase 1 0.27687
ERCC5 excision repair cross-complementation group 5 0.273308
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.272953
C1QBP complement component 1, q subcomponent binding protein 0.270108
ERCC3 excision repair cross-complementation group 3 0.262306
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.258417
C10ORF2 chromosome 10 open reading frame 2 0.253831
RFC1 replication factor C (activator 1) 1, 145kDa 0.251718
GLRX glutaredoxin (thioltransferase) 0.246799
PTRF polymerase I and transcript release factor 0.243645
SAMHD1 SAM domain and HD domain 1 0.240847
REV1 REV1, polymerase (DNA directed) 0.240497
G6PD glucose-6-phosphate dehydrogenase 0.234225
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.233183
ETV5 ets variant 5 0.230755
HDAC5 histone deacetylase 5 0.229716
IGF1 insulin-like growth factor 1 (somatomedin C) 0.225917
PGD phosphogluconate dehydrogenase 0.222479
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.21974
BCAN brevican 0.208914
POLL polymerase (DNA directed), lambda 0.208579
TMPO thymopoietin 0.205254
CRABP1 cellular retinoic acid binding protein 1 0.19582
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.195183
PTEN phosphatase and tensin homolog 0.186811
RIPK2 receptor-interacting serine-threonine kinase 2 0.185313
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.18151
NEUROG1 neurogenin 1 0.178682
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.178126
H3F3B H3 histone, family 3B (H3.3B) 0.173314
H3F3A H3 histone, family 3A 0.173314
PLG plasminogen 0.166995
FAXDC2 fatty acid hydroxylase domain containing 2 0.165217
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.164786
LOXL2 lysyl oxidase-like 2 0.163729
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.163729
RFC2 replication factor C (activator 1) 2, 40kDa 0.162908