wide pore channel activity Gene Set

Dataset GO Molecular Function Annotations 2023
Category structural or functional annotations
Type biological process
Description Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts. (Gene Ontology, GO_0022829)
External Link http://amigo.geneontology.org/amigo/term/GO:0022829
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Genes

26 genes performing the wide pore channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Symbol Name
BAK1 BCL2-antagonist/killer 1
GJA1 gap junction protein, alpha 1, 43kDa
GJA3 gap junction protein, alpha 3, 46kDa
GJA4 gap junction protein, alpha 4, 37kDa
GJA5 gap junction protein, alpha 5, 40kDa
GJA8 gap junction protein, alpha 8, 50kDa
GJA9 gap junction protein, alpha 9, 59kDa
GJB1 gap junction protein, beta 1, 32kDa
GJB2 gap junction protein, beta 2, 26kDa
GJB3 gap junction protein, beta 3, 31kDa
GJB4 gap junction protein, beta 4, 30.3kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GJB6 gap junction protein, beta 6, 30kDa
GJB7 gap junction protein, beta 7, 25kDa
GJC1 gap junction protein, gamma 1, 45kDa
GJC2 gap junction protein, gamma 2, 47kDa
GJC3 gap junction protein, gamma 3, 30.2kDa
GJD2 gap junction protein, delta 2, 36kDa
GJD4 gap junction protein, delta 4, 40.1kDa
GSDMA gasdermin A
GSDMD gasdermin D
GSDME gasdermin E
PANX1 pannexin 1
PANX2 pannexin 2
PANX3 pannexin 3
PRF1 perforin 1 (pore forming protein)