wilson disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_893)
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Genes

123 genes co-occuring with the disease wilson disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ATP7B ATPase, Cu++ transporting, beta polypeptide 3.73057
ATP7A ATPase, Cu++ transporting, alpha polypeptide 3.62508
CP ceruloplasmin (ferroxidase) 3.12325
ATOX1 antioxidant 1 copper chaperone 2.23726
DNAH8 dynein, axonemal, heavy chain 8 2.16917
COMMD1 copper metabolism (Murr1) domain containing 1 1.82549
SLITRK1 SLIT and NTRK-like family, member 1 1.44254
ESD esterase D 1.25602
COPB1 coatomer protein complex, subunit beta 1 1.10343
ALB albumin 0.930828
SOD2 superoxide dismutase 2, mitochondrial 0.904442
F2 coagulation factor II (thrombin) 0.89541
COX17 COX17 cytochrome c oxidase copper chaperone 0.881472
GCH1 GTP cyclohydrolase 1 0.848307
PANK1 pantothenate kinase 1 0.846669
ATP11A ATPase, class VI, type 11A 0.841344
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.840934
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.833148
HFE hemochromatosis 0.824948
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 0.815104
ALPPL2 alkaline phosphatase, placental-like 2 0.806488
ALPP alkaline phosphatase, placental 0.806077
ALPL alkaline phosphatase, liver/bone/kidney 0.805667
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.801564
C11ORF31 chromosome 11 open reading frame 31 0.792541
CCS copper chaperone for superoxide dismutase 0.750457
TF transferrin 0.697911
PRKG1 protein kinase, cGMP-dependent, type I 0.681894
AANAT aralkylamine N-acetyltransferase 0.681096
ARSA arylsulfatase A 0.672722
DCTN4 dynactin 4 (p62) 0.658026
MGAM maltase-glucoamylase 0.646953
DRD2 dopamine receptor D2 0.631598
COPA coatomer protein complex, subunit alpha 0.617877
PNOC prepronociceptin 0.592895
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.590948
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.572273
ASMT acetylserotonin O-methyltransferase 0.532314
HAMP hepcidin antimicrobial peptide 0.531928
THOP1 thimet oligopeptidase 1 0.531928
FTL ferritin, light polypeptide 0.531928
FTH1 ferritin, heavy polypeptide 1 0.531541
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.530768
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.528063
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 0.521117
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.502675
GGT1 gamma-glutamyltransferase 1 0.494266
AHCY adenosylhomocysteinase 0.493122
GGT2 gamma-glutamyltransferase 2 0.473361
CAT catalase 0.46655
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.463527
LOX lysyl oxidase 0.448064
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.43941
NPC1 Niemann-Pick disease, type C1 0.438282
SC5D sterol-C5-desaturase 0.438282
ANXA7 annexin A7 0.43753
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.434148
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.434148
MBD4 methyl-CpG binding domain protein 4 0.431144
GPX5 glutathione peroxidase 5 0.427765
SERAC1 serine active site containing 1 0.427765
GPX4 glutathione peroxidase 4 0.424765
IDI1 isopentenyl-diphosphate delta isomerase 1 0.416147
GPX1 glutathione peroxidase 1 0.409414
MARS methionyl-tRNA synthetase 0.401199
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.393746
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.391885
HFE2 hemochromatosis type 2 (juvenile) 0.379626
CIC capicua transcriptional repressor 0.374438
ATP13A2 ATPase type 13A2 0.372217
SSBP1 single-stranded DNA binding protein 1, mitochondrial 0.365193
VRK2 vaccinia related kinase 2 0.364454
MTF1 metal-regulatory transcription factor 1 0.361502
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.357077
NOBOX NOBOX oogenesis homeobox 0.341272
AGXT alanine-glyoxylate aminotransferase 0.336876
FN3K fructosamine 3 kinase 0.320454
PANK2 pantothenate kinase 2 0.306672
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 0.300894
RNF25 ring finger protein 25 0.300533
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.295492
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 0.293334
SCO1 SCO1 cytochrome c oxidase assembly protein 0.28151
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.274732
PTPRB protein tyrosine phosphatase, receptor type, B 0.273308
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.255241
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.250663
JAK3 Janus kinase 3 0.245747
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.244345
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.244345
MT1X metallothionein 1X 0.243645
TRIP12 thyroid hormone receptor interactor 12 0.238403
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.232489
FBXO2 F-box protein 2 0.231448
NTHL1 nth endonuclease III-like 1 (E. coli) 0.230409
MPV17 MpV17 mitochondrial inner membrane protein 0.226262
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.222479
G6PD glucose-6-phosphate dehydrogenase 0.22145
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.219398
PAM peptidylglycine alpha-amidating monooxygenase 0.217012
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.216332
KL klotho 0.210589
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.210253
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.210253
HOXC6 homeobox C6 0.209918
CA3 carbonic anhydrase III 0.203275
BIN2 bridging integrator 2 0.198709
FBLN2 fibulin 2 0.191719
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 0.190168
LCAT lecithin-cholesterol acyltransferase 0.18621
SQLE squalene epoxidase 0.185313
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.183248
VRK1 vaccinia related kinase 1 0.177576
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.177029
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.173571
TYR tyrosinase 0.165217
TFR2 transferrin receptor 2 0.164359
ACP2 acid phosphatase 2, lysosomal 0.162707
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.162707
THAP1 THAP domain containing, apoptosis associated protein 1 0.162109
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.161331
ELANE elastase, neutrophil expressed 0.160387
FBXO7 F-box protein 7 0.158778