wnt5a Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description wingless-type MMTV integration site family, member 5A|The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 7474)
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Genes

76 genes co-occuring with the biological term wnt5a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AKT1 v-akt murine thymoma viral oncogene homolog 1
APC adenomatous polyposis coli
ARRB2 arrestin, beta 2
BCL6 B-cell CLL/lymphoma 6
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CASR calcium-sensing receptor
CCL2 chemokine (C-C motif) ligand 2
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CSNK1A1 casein kinase 1, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSE cathepsin E
CUX1 cut-like homeobox 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DAAM1 dishevelled associated activator of morphogenesis 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DVL2 dishevelled segment polarity protein 2
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FRZB frizzled-related protein
FZD2 frizzled class receptor 2
FZD5 frizzled class receptor 5
GLRX glutaredoxin (thioltransferase)
GPC6 glypican 6
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IHH indian hedgehog
IL1B interleukin 1, beta
KL klotho
LRP1 low density lipoprotein receptor-related protein 1
MAPK8 mitogen-activated protein kinase 8
MCAM melanoma cell adhesion molecule
MIR26A1 microRNA 26a-1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX3-2 NK3 homeobox 2
PAX2 paired box 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRM2 protamine 2
PROM1 prominin 1
PROX1 prospero homeobox 1
RHOA ras homolog family member A
ROR2 receptor tyrosine kinase-like orphan receptor 2
S100P S100 calcium binding protein P
SDC1 syndecan 1
SDC4 syndecan 4
SFRP2 secreted frizzled-related protein 2
SFRP4 secreted frizzled-related protein 4
SFRP5 secreted frizzled-related protein 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAI1 snail family zinc finger 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
WIF1 WNT inhibitory factor 1
WNT11 wingless-type MMTV integration site family, member 11
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WNT7A wingless-type MMTV integration site family, member 7A
WNT9B wingless-type MMTV integration site family, member 9B
YES1 YES proto-oncogene 1, Src family tyrosine kinase