wound Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. (Experimental Factor Ontology, EFO_0000546)
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Genes

316 genes co-occuring with the biological term wound in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ADAM12 ADAM metallopeptidase domain 12
ADAM15 ADAM metallopeptidase domain 15
ADAM17 ADAM metallopeptidase domain 17
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
ALOX5 arachidonate 5-lipoxygenase
AMELX amelogenin, X-linked
AMY1A amylase, alpha 1A (salivary)
ANGPT2 angiopoietin 2
ANGPTL4 angiopoietin-like 4
ANGPTL6 angiopoietin-like 6
ANXA1 annexin A1
ANXA2 annexin A2
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARG1 arginase 1
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARNT aryl hydrocarbon receptor nuclear translocator
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AVP arginine vasopressin
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
BMP1 bone morphogenetic protein 1
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
BRAP BRCA1 associated protein
BSG basigin (Ok blood group)
CALML3 calmodulin-like 3
CALR calreticulin
CAMP cathelicidin antimicrobial peptide
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL27 chemokine (C-C motif) ligand 27
CCR3 chemokine (C-C motif) receptor 3
CDC42 cell division cycle 42
CDC42SE2 CDC42 small effector 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC7A C-type lectin domain family 7, member A
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
COL7A1 collagen, type VII, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CREB1 cAMP responsive element binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CTF1 cardiotrophin 1
CTGF connective tissue growth factor
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSD cathepsin D
CTSF cathepsin F
CTSG cathepsin G
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
DCN decorin
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFB4A defensin, beta 4A
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMKN dermokine
DPP4 dipeptidyl-peptidase 4
DPT dermatopontin
E2F3 E2F transcription factor 3
EDN1 endothelin 1
EFNB2 ephrin-B2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ELAVL1 ELAV like RNA binding protein 1
ENG endoglin
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F13A1 coagulation factor XIII, A1 polypeptide
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAP fibroblast activation protein, alpha
FAT1 FAT atypical cadherin 1
FBN2 fibrillin 2
FBRS fibrosin
FGF2 fibroblast growth factor 2 (basic)
FGF7 fibroblast growth factor 7
FGFBP1 fibroblast growth factor binding protein 1
FGFR1 fibroblast growth factor receptor 1
FGFR1OP2 FGFR1 oncogene partner 2
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FLII flightless I homolog (Drosophila)
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRS2 fibroblast growth factor receptor substrate 2
FSTL1 follistatin-like 1
GAS6 growth arrest-specific 6
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GRN granulin
GSTP1 glutathione S-transferase pi 1
HBEGF heparin-binding EGF-like growth factor
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AA2P heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene
HSPA4 heat shock 70kDa protein 4
HSPG2 heparan sulfate proteoglycan 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDE insulin-degrading enzyme
IFNA2 interferon, alpha 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL2 interferon, lambda 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP5 insulin-like growth factor binding protein 5
IL10 interleukin 10
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL22 interleukin 22
IL24 interleukin 24
IL33 interleukin 33
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
INS insulin
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
ITGB6 integrin, beta 6
JAK3 Janus kinase 3
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KANK1 KN motif and ankyrin repeat domains 1
KAT5 K(lysine) acetyltransferase 5
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LAMA3 laminin, alpha 3
LAMA5 laminin, alpha 5
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LARP6 La ribonucleoprotein domain family, member 6
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS7 lectin, galactoside-binding, soluble, 7
LRP1 low density lipoprotein receptor-related protein 1
LTF lactotransferrin
LUM lumican
LYPD3 LY6/PLAUR domain containing 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPK9 mitogen-activated protein kinase 9
MATN2 matrilin 2
MECP2 methyl CpG binding protein 2
MERTK MER proto-oncogene, tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR100 microRNA 100
MIR198 microRNA 198
MIR199A1 microRNA 199a-1
MIR199A2 microRNA 199a-2
MIR21 microRNA 21
MIR210 microRNA 210
MIR27B microRNA 27b
MIR483 microRNA 483
MIR99A microRNA 99a
MIR99B microRNA 99b
MKI67 marker of proliferation Ki-67
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MYO10 myosin X
MYO9B myosin IXB
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCOA3 nuclear receptor coactivator 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NOS1 nitric oxide synthase 1 (neuronal)
NOTCH1 notch 1
NOV nephroblastoma overexpressed
NOX1 NADPH oxidase 1
NREP neuronal regeneration related protein
NRG1 neuregulin 1
NTS neurotensin
OXT oxytocin/neurophysin I prepropeptide
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP1 poly (ADP-ribose) polymerase 1
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDPN podoplanin
PEX2 peroxisomal biogenesis factor 2
PEX5L peroxisomal biogenesis factor 5-like
PGF placental growth factor
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
POSTN periostin, osteoblast specific factor
PPARD peroxisome proliferator-activated receptor delta
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCE protein kinase C, epsilon
PTEN phosphatase and tensin homolog
PTK2B protein tyrosine kinase 2 beta
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REG3A regenerating islet-derived 3 alpha
RGS5 regulator of G-protein signaling 5
RHOA ras homolog family member A
RHOC ras homolog family member C
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK4 receptor-interacting serine-threonine kinase 4
RLN2 relaxin 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNX2 runt-related transcription factor 2
RXFP1 relaxin/insulin-like family peptide receptor 1
SCARB1 scavenger receptor class B, member 1
SCG2 secretogranin II
SDC1 syndecan 1
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIRT1 sirtuin 1
SLPI secretory leukocyte peptidase inhibitor
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRR2A small proline-rich protein 2A
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF6 serine/arginine-rich splicing factor 6
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYNPO synaptopodin
TAC1 tachykinin, precursor 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNC tenascin C
TNF tumor necrosis factor
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNXB tenascin XB
TP53 tumor protein p53
TP63 tumor protein p63
TREM1 triggering receptor expressed on myeloid cells 1
VCAN versican
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VIM vimentin
VIP vasoactive intestinal peptide
VSX1 visual system homeobox 1
VTN vitronectin
WNT7A wingless-type MMTV integration site family, member 7A
ZBED6 zinc finger, BED-type containing 6
ZFP36L1 ZFP36 ring finger protein-like 1