wt1_17088532_huvec_lof_human_gpl570_gds2010 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS2010
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Genes

117 genes differentially expressed following the wt1_17088532_huvec_lof_human_gpl570_gds2010 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
FAM69A family with sequence similarity 69, member A 2.38762
FAM91A1 family with sequence similarity 91, member A1 2.37645
SEC23IP SEC23 interacting protein 2.32725
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.28466
AURKB aurora kinase B 2.02923
IQCG IQ motif containing G 1.99567
RCOR3 REST corepressor 3 1.89292
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 1.77556
SH3PXD2A SH3 and PX domains 2A 1.7355
PRDX2 peroxiredoxin 2 1.73221
KRTAP2-1 keratin associated protein 2-1 1.6552
RUVBL1 RuvB-like AAA ATPase 1 1.62312
ORAI2 ORAI calcium release-activated calcium modulator 2 1.58917
PAWR PRKC, apoptosis, WT1, regulator 1.45388
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 1.45013
KIAA1109 KIAA1109 1.41335
CFB complement factor B 1.41165
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.40689
INPP1 inositol polyphosphate-1-phosphatase 1.32439
MOXD1 monooxygenase, DBH-like 1 1.27507
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 1.2705
CLIC4 chloride intracellular channel 4 1.26802
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.11127
PPP1R3D protein phosphatase 1, regulatory subunit 3D 1.05468
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 1.00798
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.988938
MAT2A methionine adenosyltransferase II, alpha 0.944389
NHSL1 NHS-like 1 0.899003
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 0.892048
KANSL1L KAT8 regulatory NSL complex subunit 1-like 0.841698
LHFPL4 lipoma HMGIC fusion partner-like 4 0.748188
TEAD2 TEA domain family member 2 0.624098
TMEM206 transmembrane protein 206 0.514417
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 0.448388
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.410657
LINC00309 long intergenic non-protein coding RNA 309 0.379849
ZDHHC13 zinc finger, DHHC-type containing 13 0.379849
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.369792
SEC62 SEC62 homolog (S. cerevisiae) 0.312256
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.302809
DICER1-AS1 DICER1 antisense RNA 1 0.298655
CLMN calmin (calponin-like, transmembrane) 0.281207
HMGA2 high mobility group AT-hook 2 0.27741
RNASEH2B ribonuclease H2, subunit B 0.261683
SLC43A3 solute carrier family 43, member 3 0.254168
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 0.249361
FANCB Fanconi anemia, complementation group B 0.235548
TM9SF3 transmembrane 9 superfamily member 3 0.186944
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.125591
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.048391
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.014717

decreased expression

Symbol Name Standardized Value
SLC4A3 solute carrier family 4 (anion exchanger), member 3 -0.662592
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -0.662592
CALML3 calmodulin-like 3 -0.662592
SUSD3 sushi domain containing 3 -0.662592
DIRAS1 DIRAS family, GTP-binding RAS-like 1 -0.662592
SURF1 surfeit 1 -0.662592
RNASET2 ribonuclease T2 -0.662592
TRD T cell receptor delta locus -0.662592
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 -0.662592
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -0.371282
METTL2A methyltransferase like 2A -0.370178
CCT2 chaperonin containing TCP1, subunit 2 (beta) -0.365152
IQCH IQ motif containing H -0.3614
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.3614
BCAN brevican -0.354582
SNORD114-3 small nucleolar RNA, C/D box 114-3 -0.354582
IWS1 IWS1 homolog (S. cerevisiae) -0.354582
SYNDIG1 synapse differentiation inducing 1 -0.354582
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -0.336847
MIR7-3HG MIR7-3 host gene -0.313591
ABLIM2 actin binding LIM protein family, member 2 -0.300548
HDC histidine decarboxylase -0.300548
TMEM33 transmembrane protein 33 -0.299825
SMIM3 small integral membrane protein 3 -0.294966
CHMP1A charged multivesicular body protein 1A -0.28624
C19ORF48 chromosome 19 open reading frame 48 -0.281293
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) -0.273802
CERS5 ceramide synthase 5 -0.270926
MTBP MDM2 binding protein -0.270926
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -0.265267
FAM181B family with sequence similarity 181, member B -0.256142
ANO2 anoctamin 2, calcium activated chloride channel -0.254453
MAP1B microtubule-associated protein 1B -0.254394
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.254394
SYT4 synaptotagmin IV -0.251127
GMPS guanine monphosphate synthase -0.244971
WFDC8 WAP four-disulfide core domain 8 -0.239404
OSBPL7 oxysterol binding protein-like 7 -0.237448
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.237419
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.222669
CCDC155 coiled-coil domain containing 155 -0.219774
FSCN1 fascin actin-bundling protein 1 -0.219473
KIZ kizuna centrosomal protein -0.202779
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.202427
MRPL9 mitochondrial ribosomal protein L9 -0.188349
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -0.187583
PGK1 phosphoglycerate kinase 1 -0.186317
PNRC2 proline-rich nuclear receptor coactivator 2 -0.18583
TJP3 tight junction protein 3 -0.169388
WNT2B wingless-type MMTV integration site family, member 2B -0.1655
RTEL1 regulator of telomere elongation helicase 1 -0.159447
PHYH phytanoyl-CoA 2-hydroxylase -0.154706
HLA-DOB major histocompatibility complex, class II, DO beta -0.154706
IL20RA interleukin 20 receptor, alpha -0.151732
SIGLEC7 sialic acid binding Ig-like lectin 7 -0.151732
COL5A2 collagen, type V, alpha 2 -0.142187
LOC728485 uncharacterized LOC728485 -0.128923
WBP4 WW domain binding protein 4 -0.126237
UXS1 UDP-glucuronate decarboxylase 1 -0.119431
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -0.091648
HACL1 2-hydroxyacyl-CoA lyase 1 -0.067741
PLLP plasmolipin -0.060914
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.045555
SASH3 SAM and SH3 domain containing 3 -0.043649
RPL3 ribosomal protein L3 -0.043649
ZNF492 zinc finger protein 492 -0.026001