x-linked disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A monogenic disease that has_material_basis_in muations in genes on the X chromosome. (Human Disease Ontology, DOID_0050735)
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Genes

682 genes co-occuring with the disease x-linked disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FMR1 fragile X mental retardation 1 4.15374
WAS Wiskott-Aldrich syndrome 2.62553
OCRL oculocerebrorenal syndrome of Lowe 2.50177
STS steroid sulfatase (microsomal), isozyme S 2.50017
TAZ tafazzin 2.38299
FXR2 fragile X mental retardation, autosomal homolog 2 2.2298
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 2.10904
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 2.06487
GRM5 glutamate receptor, metabotropic 5 2.00791
AFF2 AF4/FMR2 family, member 2 1.96755
EFNB1 ephrin-B1 1.95253
FXR1 fragile X mental retardation, autosomal homolog 1 1.84545
F8 coagulation factor VIII, procoagulant component 1.81374
SPN sialophorin 1.72456
PORCN porcupine homolog (Drosophila) 1.72365
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 1.657
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 1.61262
CDC42 cell division cycle 42 1.44913
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 1.43376
MED12 mediator complex subunit 12 1.43157
GLA galactosidase, alpha 1.41665
WIPF1 WAS/WASL interacting protein family, member 1 1.40089
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 1.3869
OTC ornithine carbamoyltransferase 1.38516
IDS iduronate 2-sulfatase 1.36858
ARSH arylsulfatase family, member H 1.3494
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.30445
MAP1B microtubule-associated protein 1B 1.27606
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 1.2508
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 1.23256
CLCN5 chloride channel, voltage-sensitive 5 1.20439
ST14 suppression of tumorigenicity 14 (colon carcinoma) 1.20223
F9 coagulation factor IX 1.2018
GRM1 glutamate receptor, metabotropic 1 1.191
VCX3B variable charge, X-linked 3B 1.17722
F5 coagulation factor V (proaccelerin, labile factor) 1.17292
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 1.15965
LMAN1 lectin, mannose-binding, 1 1.1473
VCX3A variable charge, X-linked 3A 1.14602
MECP2 methyl CpG binding protein 2 1.13585
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 1.11351
DLG3 discs, large homolog 3 (Drosophila) 1.1051
WASH7P WAS protein family homolog 7 pseudogene 1.08873
WASH1 WAS protein family homolog 1 1.08454
WASH6P WAS protein family homolog 6 pseudogene 1.08202
TMEM185A transmembrane protein 185A 1.07572
NDP Norrie disease (pseudoglioma) 1.06648
OPHN1 oligophrenin 1 1.06438
AR androgen receptor 1.04756
TBC1D3F TBC1 domain family, member 3F 1.02271
TBC1D3 TBC1 domain family, member 3 1.02271
PRPS1 phosphoribosyl pyrophosphate synthetase 1 1.02187
PHF6 PHD finger protein 6 1.02144
DMD dystrophin 1.02102
FMR1-AS1 FMR1 antisense RNA 1 0.999503
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.995705
FOXP3 forkhead box P3 0.994017
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 0.993174
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.975482
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.97086
MCFD2 multiple coagulation factor deficiency 2 0.97002
NRF1 nuclear respiratory factor 1 0.956196
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.954525
VCX variable charge, X-linked 0.953273
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.951187
ARHGAP1 Rho GTPase activating protein 1 0.944106
VCX2 variable charge, X-linked 2 0.927105
WASL Wiskott-Aldrich syndrome-like 0.919261
KCNT2 potassium channel, sodium activated subfamily T, member 2 0.911022
XG Xg blood group 0.91061
DICER1 dicer 1, ribonuclease type III 0.908142
DTNA dystrobrevin, alpha 0.899514
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.88393
VCY1B variable charge, Y-linked 1B 0.865912
VCY variable charge, Y-linked 0.865912
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.865912
F3 coagulation factor III (thromboplastin, tissue factor) 0.856087
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.85404
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.851583
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.829049
TBX22 T-box 22 0.828639
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.826589
SH2D1A SH2 domain containing 1A 0.814693
HYDIN HYDIN, axonemal central pair apparatus protein 0.80977
FLG filaggrin 0.804026
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2 0.797462
WASF2 WAS protein family, member 2 0.796232
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.795002
AGO1 argonaute RISC catalytic component 1 0.786394
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.777386
AMER1 APC membrane recruitment protein 1 0.767985
XK X-linked Kx blood group 0.767576
ATG4C autophagy related 4C, cysteine peptidase 0.761047
BCOR BCL6 corepressor 0.757786
MSL3 male-specific lethal 3 homolog (Drosophila) 0.753713
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.748424
WDR45 WD repeat domain 45 0.745985
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.738271
C17ORF70 chromosome 17 open reading frame 70 0.737054
CAPRIN1 cell cycle associated protein 1 0.728143
CGGBP1 CGG triplet repeat binding protein 1 0.727333
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.725311
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.721673
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.71925
ATL1 atlastin GTPase 1 0.715215
ZNF41 zinc finger protein 41 0.714005
FYN FYN proto-oncogene, Src family tyrosine kinase 0.712392
GDI1 GDP dissociation inhibitor 1 0.711183
IGSF1 immunoglobulin superfamily, member 1 0.705949
PCDH19 protocadherin 19 0.702732
WIPF3 WAS/WASL interacting protein family, member 3 0.693499
SERAC1 serine active site containing 1 0.693499
G6PD glucose-6-phosphate dehydrogenase 0.693098
KIAA1109 KIAA1109 0.690694
FGD1 FYVE, RhoGEF and PH domain containing 1 0.688291
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.683093
AUH AU RNA binding protein/enoyl-CoA hydratase 0.675112
UBL4A ubiquitin-like 4A 0.67113
GRB2 growth factor receptor-bound protein 2 0.668742
TRIP10 thyroid hormone receptor interactor 10 0.668345
LIG3 ligase III, DNA, ATP-dependent 0.666358
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.666358
SKP1 S-phase kinase-associated protein 1 0.663975
ARMCX2 armadillo repeat containing, X-linked 2 0.663975
ZNF81 zinc finger protein 81 0.663975
VWF von Willebrand factor 0.66199
TDRD3 tudor domain containing 3 0.661594
AVPR2 arginine vasopressin receptor 2 0.6608
HCCS holocytochrome c synthase 0.658422
GPC3 glypican 3 0.654463
BDNF brain-derived neurotrophic factor 0.653276
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 0.647348
PLEK pleckstrin 0.641039
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.635921
TSPAN7 tetraspanin 7 0.635528
GPC4 glypican 4 0.632384
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.630813
NCKAP1L NCK-associated protein 1-like 0.63042
PLP1 proteolipid protein 1 0.629635
PFN1 profilin 1 0.629242
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 0.627672
NXF1 nuclear RNA export factor 1 0.626495
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.621008
NLGN3 neuroligin 3 0.619834
AGO2 argonaute RISC catalytic component 2 0.615138
DNM2 dynamin 2 0.61162
COL4A5 collagen, type IV, alpha 5 0.60264
CFP complement factor properdin 0.60108
SETD5 SET domain containing 5 0.598351
WASF1 WAS protein family, member 1 0.595623
TEX28 testis expressed 28 0.594064
TEX28P2 testis expressed 28 pseudogene 2 0.594064
NOVA1 neuro-oncological ventral antigen 1 0.593285
PQBP1 polyglutamine binding protein 1 0.584719
NXF2B nuclear RNA export factor 2B 0.580439
NXF2 nuclear RNA export factor 2 0.580439
RAB2B RAB2B, member RAS oncogene family 0.577327
AMPD1 adenosine monophosphate deaminase 1 0.576161
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.575772
CD4 CD4 molecule 0.575383
CD40LG CD40 ligand 0.575383
MTFMT mitochondrial methionyl-tRNA formyltransferase 0.572662
PGK1 phosphoglycerate kinase 1 0.572662
FLNA filamin A, alpha 0.572273
C19ORF40 chromosome 19 open reading frame 40 0.568775
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.568386
CD79A CD79a molecule, immunoglobulin-associated alpha 0.568386
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 0.567997
TGM1 transglutaminase 1 0.564889
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 0.563335
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.563335
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.561781
TMEM70 transmembrane protein 70 0.559839
FKBP15 FK506 binding protein 15, 133kDa 0.557897
SYNJ1 synaptojanin 1 0.554015
RIT1 Ras-like without CAAX 1 0.550911
MSL2 male-specific lethal 2 homolog (Drosophila) 0.550134
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.545868
SUMF1 sulfatase modifying factor 1 0.544318
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.538893
USF2 upstream transcription factor 2, c-fos interacting 0.534635
FGD3 FYVE, RhoGEF and PH domain containing 3 0.532701
VASP vasodilator-stimulated phosphoprotein 0.532314
HOMER1 homer scaffolding protein 1 0.531928
MBTPS2 membrane-bound transcription factor peptidase, site 2 0.529608
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.528835
GLRA2 glycine receptor, alpha 2 0.524974
AMELX amelogenin, X-linked 0.52343
GPHN gephyrin 0.521502
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.520731
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.51919
RBM10 RNA binding motif protein 10 0.516494
SYNJ2 synaptojanin 2 0.509959
PFN4 profilin family, member 4 0.508424
SYTL4 synaptotagmin-like 4 0.50689
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.504973
L1CAM L1 cell adhesion molecule 0.497703
CD34 CD34 molecule 0.493122
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 0.491978
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.490835
RASA2 RAS p21 protein activator 2 0.48893
PTER phosphotriesterase related 0.483224
KIF3C kinesin family member 3C 0.482084
INPPL1 inositol polyphosphate phosphatase-like 1 0.481705
NLGN4X neuroligin 4, X-linked 0.479807
LAMP2 lysosomal-associated membrane protein 2 0.479047
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.47753
KEL Kell blood group, metallo-endopeptidase 0.476014
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.472982
LCLAT1 lysocardiolipin acyltransferase 1 0.472982
TOP3B topoisomerase (DNA) III beta 0.462772
GK glycerol kinase 0.460883
ZNF711 zinc finger protein 711 0.456355
INPP5K inositol polyphosphate-5-phosphatase K 0.45447
DACH2 dachshund family transcription factor 2 0.452585
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.449947
DCLK2 doublecortin-like kinase 2 0.449947
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.446558
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.442042
PFN2 profilin 2 0.442042
AMELY amelogenin, Y-linked 0.437906
HDLBP high density lipoprotein binding protein 0.435651
EFHC2 EF-hand domain (C-terminal) containing 2 0.434899
GOLGA5 golgin A5 0.428891
ASIC2 acid sensing (proton gated) ion channel 2 0.428516
PHKA2 phosphorylase kinase, alpha 2 (liver) 0.424014
LMO2 LIM domain only 2 (rhombotin-like 1) 0.423265
PI16 peptidase inhibitor 16 0.422515
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.421016
RGS4 regulator of G-protein signaling 4 0.419142
LDB3 LIM domain binding 3 0.418019
BAIAP2L1 BAI1-associated protein 2-like 1 0.41727
TMOD2 tropomodulin 2 (neuronal) 0.412779
CD99 CD99 molecule 0.410161
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.408666
MAOA monoamine oxidase A 0.406798
HAX1 HCLS1 associated protein X-1 0.404931
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.404557
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.400826
DNAH8 dynein, axonemal, heavy chain 8 0.400826
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 0.400453
DMPK dystrophia myotonica-protein kinase 0.398589
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.397843
DNASE1L1 deoxyribonuclease I-like 1 0.396725
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.396353
H3F3B H3 histone, family 3B (H3.3B) 0.394118
H3F3A H3 histone, family 3A 0.394118
GOLGA4 golgin A4 0.393746
JMY junction mediating and regulatory protein, p53 cofactor 0.390025
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.387051
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.382223
ATP13A1 ATPase type 13A1 0.381852
PTPRD protein tyrosine phosphatase, receptor type, D 0.380739
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.380368
NEK4 NIMA-related kinase 4 0.378885
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 0.377402
TTC7A tetratricopeptide repeat domain 7A 0.374438
CEND1 cell cycle exit and neuronal differentiation 1 0.373328
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.373328
RAI2 retinoic acid induced 2 0.371107
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.369997
OFD1 oral-facial-digital syndrome 1 0.369997
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.365562
KDM5C lysine (K)-specific demethylase 5C 0.364824
CREB1 cAMP responsive element binding protein 1 0.361133
RANBP9 RAN binding protein 9 0.359289
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 0.353395
ASTN2 astrotactin 2 0.350452
BTK Bruton agammaglobulinemia tyrosine kinase 0.350084
COG4 component of oligomeric golgi complex 4 0.349349
FOS FBJ murine osteosarcoma viral oncogene homolog 0.349349
RPS6 ribosomal protein S6 0.348246
WASF3 WAS protein family, member 3 0.347879
RAB6A RAB6A, member RAS oncogene family 0.346409
EIF4E eukaryotic translation initiation factor 4E 0.343106
ADA adenosine deaminase 0.342739
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 0.340906
RBM4 RNA binding motif protein 4 0.33944
F2 coagulation factor II (thrombin) 0.337242
IGBP1 immunoglobulin (CD79A) binding protein 1 0.336876
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.33651
MYH9 myosin, heavy chain 9, non-muscle 0.333583
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.332852
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.332121
INTS8 integrator complex subunit 8 0.332121
GAMT guanidinoacetate N-methyltransferase 0.328105
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.327375
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 0.326646
WLS wntless Wnt ligand secretion mediator 0.324458
PTK2 protein tyrosine kinase 2 0.323365
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.323002
HLA-C major histocompatibility complex, class I, C 0.322273
ALX3 ALX homeobox 3 0.321909
FOXL2 forkhead box L2 0.32009
CALB1 calbindin 1, 28kDa 0.32009
PRMT1 protein arginine methyltransferase 1 0.319726
S100G S100 calcium binding protein G 0.317545
TERF2 telomeric repeat binding factor 2 0.316092
CKAP5 cytoskeleton associated protein 5 0.316092
TMOD1 tropomodulin 1 0.31464
INSC inscuteable homolog (Drosophila) 0.314278
PRKX protein kinase, X-linked 0.312464
ALX1 ALX homeobox 1 0.312102
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) 0.308118
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.308118
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.307757
LINC00207 long intergenic non-protein coding RNA 207 0.307395
BCLAF1 BCL2-associated transcription factor 1 0.306672
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.306672
USF1 upstream transcription factor 1 0.304864
REPS2 RALBP1 associated Eps domain containing 2 0.303781
G6PC3 glucose 6 phosphatase, catalytic, 3 0.300533
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.299812
DOCK8 dedicator of cytokinesis 8 0.295132
ARF1 ADP-ribosylation factor 1 0.294772
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 0.293334
NCK2 NCK adaptor protein 2 0.293334
PKN1 protein kinase N1 0.292616
PGD phosphogluconate dehydrogenase 0.292616
PLCG1 phospholipase C, gamma 1 0.290103
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.289744
MCRS1 microspherule protein 1 0.287952
CTTN cortactin 0.287952
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.284371
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.283655
CC2D1A coiled-coil and C2 domain containing 1A 0.275445
CD47 CD47 molecule 0.275445
SHANK1 SH3 and multiple ankyrin repeat domains 1 0.275089
ARSA arylsulfatase A 0.273308
FNBP1 formin binding protein 1 0.27153
GRPR gastrin-releasing peptide receptor 0.270464
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.269753
BASP1 brain abundant, membrane attached signal protein 1 0.269398
RHOQ ras homolog family member Q 0.269398
STARD8 StAR-related lipid transfer (START) domain containing 8 0.267622
SOX3 SRY (sex determining region Y)-box 3 0.267622
KDM4A lysine (K)-specific demethylase 4A 0.265849
ANO6 anoctamin 6 0.264785
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.263722
GLYATL1 glycine-N-acyltransferase-like 1 0.259124
RPL32 ribosomal protein L32 0.257358
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.257005
TSEN54 TSEN54 tRNA splicing endonuclease subunit 0.256652
BSND barttin CLCNK-type chloride channel accessory beta subunit 0.253831
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 0.253479
FANCM Fanconi anemia, complementation group M 0.248905
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.248554
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.248203
HIST1H4F histone cluster 1, H4f 0.24715
HIST1H4J histone cluster 1, H4j 0.24715
HIST1H4E histone cluster 1, H4e 0.24715
HIST1H4K histone cluster 1, H4k 0.24715
HIST1H4A histone cluster 1, H4a 0.24715
HIST1H4D histone cluster 1, H4d 0.24715
HIST1H4I histone cluster 1, H4i 0.24715
HIST1H4C histone cluster 1, H4c 0.24715
HIST2H4B histone cluster 2, H4b 0.24715
HIST1H4B histone cluster 1, H4b 0.24715
HIST1H4H histone cluster 1, H4h 0.24715
PEG10 paternally expressed 10 0.246799
HIST2H4A histone cluster 2, H4a 0.246448
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.245747
HIST1H4L histone cluster 1, H4l 0.245046
HIST4H4 histone cluster 4, H4 0.244696
NYX nyctalopin 0.241546
DLG4 discs, large homolog 4 (Drosophila) 0.240847
SYNGAP1 synaptic Ras GTPase activating protein 1 0.240148
DMTN dematin actin binding protein 0.238054
RAB1B RAB1B, member RAS oncogene family 0.237706
RAB40AL RAB40A, member RAS oncogene family-like 0.23666
BAIAP2 BAI1-associated protein 2 0.236312
SBF1 SET binding factor 1 0.235616
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.235268
SP1 Sp1 transcription factor 0.23492
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 0.234573
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.234573
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.23353
YIPF2 Yip1 domain family, member 2 0.233183
AIRE autoimmune regulator 0.231448
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.229716
STAU1 staufen double-stranded RNA binding protein 1 0.227988
TMOD4 tropomodulin 4 (muscle) 0.227642
DCX doublecortin 0.225573
CLDN16 claudin 16 0.22454
FMN1 formin 1 0.223853
TNMD tenomodulin 0.222822
TFE3 transcription factor binding to IGHM enhancer 3 0.222479
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.221793
ST7 suppression of tumorigenicity 7 0.22145
DIAPH3 diaphanous-related formin 3 0.22145
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 0.221108
TARP TCR gamma alternate reading frame protein 0.218034
FANCI Fanconi anemia, complementation group I 0.216672
UNC13B unc-13 homolog B (C. elegans) 0.216332
GFI1 growth factor independent 1 transcription repressor 0.216332
NRXN1 neurexin 1 0.213621
ATF4 activating transcription factor 4 0.212608
CD81 CD81 molecule 0.211597
RBBP5 retinoblastoma binding protein 5 0.208579
ZMYM3 zinc finger, MYM-type 3 0.208245
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.206248
EFNA2 ephrin-A2 0.205585
BCAP31 B-cell receptor-associated protein 31 0.204593
CHM choroideremia (Rab escort protein 1) 0.199681
NF1 neurofibromin 1 0.199681
UBE3A ubiquitin protein ligase E3A 0.19582
IVL involucrin 0.1936
MSN moesin 0.192657
CDKL5 cyclin-dependent kinase-like 5 0.192657
WNT3A wingless-type MMTV integration site family, member 3A 0.192031
F12 coagulation factor XII (Hageman factor) 0.191408
ADRBK1 adrenergic, beta, receptor kinase 1 0.190168
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 0.188326
TSPAN1 tetraspanin 1 0.185612
RBM5 RNA binding motif protein 5 0.18472
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.183248
FSHR follicle stimulating hormone receptor 0.182086
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.181798
DIAPH2 diaphanous-related formin 2 0.179239
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.17896
HTT huntingtin 0.177301
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.176757
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.176215
CARS cysteinyl-tRNA synthetase 0.174093
ALAS2 5'-aminolevulinate synthase 2 0.173314
NOP10 NOP10 ribonucleoprotein 0.172291
NCK1 NCK adaptor protein 1 0.172038
LMNA lamin A/C 0.170544
ECEL1 endothelin converting enzyme-like 1 0.170299
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.167915
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 0.167915
CD19 CD19 molecule 0.166995
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.166995
MPL MPL proto-oncogene, thrombopoietin receptor 0.166544
ITSN1 intersectin 1 (SH3 domain protein) 0.166319
UNG uracil-DNA glycosylase 0.165874
HCFC1 host cell factor C1 0.165001
SRSF2 serine/arginine-rich splicing factor 2 0.163111
HOXB8 homeobox B8 0.161523
AFF3 AF4/FMR2 family, member 3 0.160574
EMD emerin 0.160021
CLCNKB chloride channel, voltage-sensitive Kb 0.160021
POLG polymerase (DNA directed), gamma 0.159838
SPAST spastin 0.158434
EPHB2 EPH receptor B2 0.158097
ESX1 ESX homeobox 1 0.157602
AGK acylglycerol kinase 0.157602
HOXB4 homeobox B4 0.138711
GZMK granzyme K (granzyme 3; tryptase II) 0.1342
SP7 Sp7 transcription factor 0.133544
ADSL adenylosuccinate lyase 0.133003
MECOM MDS1 and EVI1 complex locus 0.132736
ARID1B AT rich interactive domain 1B (SWI1-like) 0.130425
RCOR1 REST corepressor 1 0.129773
EFNB2 ephrin-B2 0.127934
MSMB microseminoprotein, beta- 0.127231
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.126864
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.126069
STXBP1 syntaxin binding protein 1 0.125899
MYBPC1 myosin binding protein C, slow type 0.125748
ALX4 ALX homeobox 4 0.125485
ARID1A AT rich interactive domain 1A (SWI-like) 0.125207
THRSP thyroid hormone responsive 0.124855
BANF1 barrier to autointegration factor 1 0.124552
REST RE1-silencing transcription factor 0.12454
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.123712
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.122889
ORM1 orosomucoid 1 0.122682
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.122682
MID2 midline 2 0.122591
PAX3 paired box 3 0.122565
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.121282
VDAC1 voltage-dependent anion channel 1 0.120518
PLD1 phospholipase D1, phosphatidylcholine-specific 0.120075
COL5A1 collagen, type V, alpha 1 0.12
KLF10 Kruppel-like factor 10 0.119954
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.11971
RAB5A RAB5A, member RAS oncogene family 0.119618
PNP purine nucleoside phosphorylase 0.119312
AK1 adenylate kinase 1 0.118569
PHEX phosphate regulating endopeptidase homolog, X-linked 0.118161
MAPK11 mitogen-activated protein kinase 11 0.117767
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.117565
POU3F4 POU class 3 homeobox 4 0.117211
GJA1 gap junction protein, alpha 1, 43kDa 0.116185
CKM creatine kinase, muscle 0.116131
EPHB4 EPH receptor B4 0.116006
GJB4 gap junction protein, beta 4, 30.3kDa 0.115575
IFT122 intraflagellar transport 122 0.115208
DACH1 dachshund family transcription factor 1 0.114875
GNMT glycine N-methyltransferase 0.114328
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.113832
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.11338
RAB1A RAB1A, member RAS oncogene family 0.113262
ASMT acetylserotonin O-methyltransferase 0.113243
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.112604
ARSE arylsulfatase E (chondrodysplasia punctata 1) 0.112584
KRT12 keratin 12, type I 0.112017
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.111308
BAD BCL2-associated agonist of cell death 0.111204
COX5A cytochrome c oxidase subunit Va 0.111183
TACSTD2 tumor-associated calcium signal transducer 2 0.109561
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 0.109318
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.109274
GNPAT glyceronephosphate O-acyltransferase 0.109186
SSB Sjogren syndrome antigen B (autoantigen La) 0.108144
THRB thyroid hormone receptor, beta 0.107679
RAB8A RAB8A, member RAS oncogene family 0.107049
KRT86 keratin 86, type II 0.106067
EPHA2 EPH receptor A2 0.105972
CIB1 calcium and integrin binding 1 (calmyrin) 0.105875
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.105653
KRT6A keratin 6A, type II 0.105555
KRT3 keratin 3, type II 0.105259
ALDOA aldolase A, fructose-bisphosphate 0.104741
TOB1 transducer of ERBB2, 1 0.104691
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.104211
GJB3 gap junction protein, beta 3, 31kDa 0.104009
SGSH N-sulfoglucosamine sulfohydrolase 0.103732
UBIAD1 UbiA prenyltransferase domain containing 1 0.103681
WIPF2 WAS/WASL interacting protein family, member 2 0.103449
THPO thrombopoietin 0.103268
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.103035
KAT2B K(lysine) acetyltransferase 2B 0.102543
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.102492
COL7A1 collagen, type VII, alpha 1 0.101272
MAP2K1 mitogen-activated protein kinase kinase 1 0.101272
CD5 CD5 molecule 0.101164
CD53 CD53 molecule 0.101109
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.101109
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.100838
AMPH amphiphysin 0.100024
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.099885
FERMT3 fermitin family member 3 0.09944
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 0.098718
CCL19 chemokine (C-C motif) ligand 19 0.098689
TBX21 T-box 21 0.098661
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.098348
KAT5 K(lysine) acetyltransferase 5 0.098121
SHOX short stature homeobox 0.098065
SOX10 SRY (sex determining region Y)-box 10 0.098008
HSF1 heat shock transcription factor 1 0.097526
KRT17 keratin 17, type I 0.097121
LAX1 lymphocyte transmembrane adaptor 1 0.095927
EDN3 endothelin 3 0.09578
CXCR4 chemokine (C-X-C motif) receptor 4 0.095572
CARD11 caspase recruitment domain family, member 11 0.095395
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.0951
IGF2R insulin-like growth factor 2 receptor 0.094351
KRT16 keratin 16, type I 0.09429
IL2 interleukin 2 0.094109
TNC tenascin C 0.093959
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.093537
ICT1 immature colon carcinoma transcript 1 0.093292
EDA ectodysplasin A 0.093077
CCL21 chemokine (C-C motif) ligand 21 0.092954
KRT10 keratin 10, type I 0.092893
RUNX1 runt-related transcription factor 1 0.092831
ITM2B integral membrane protein 2B 0.092555
MARK3 MAP/microtubule affinity-regulating kinase 3 0.092463
MARK2 MAP/microtubule affinity-regulating kinase 2 0.092401
CREBBP CREB binding protein 0.092309
KRT1 keratin 1, type II 0.092001
TMC6 transmembrane channel-like 6 0.091875
BCAR1 breast cancer anti-estrogen resistance 1 0.091813
LGALS7 lectin, galactoside-binding, soluble, 7 0.091781
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.091719
CALB2 calbindin 2 0.091031
HIST2H2AC histone cluster 2, H2ac 0.091
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.091
HIST2H2AA4 histone cluster 2, H2aa4 0.090969
HIST2H2AA3 histone cluster 2, H2aa3 0.090969
CXCL12 chemokine (C-X-C motif) ligand 12 0.09075
RAG2 recombination activating gene 2 0.090242
CXCL13 chemokine (C-X-C motif) ligand 13 0.09021
COL2A1 collagen, type II, alpha 1 0.089924
TADA1 transcriptional adaptor 1 0.089701
LAMP3 lysosomal-associated membrane protein 3 0.089257
IGHV4-34 immunoglobulin heavy variable 4-34 0.089192
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.089063
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.089063
ELANE elastase, neutrophil expressed 0.088901
CTCF CCCTC-binding factor (zinc finger protein) 0.088869
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.088578
CD69 CD69 molecule 0.088449
SAR1A secretion associated, Ras related GTPase 1A 0.088449
ATM ATM serine/threonine kinase 0.088416
NLGN1 neuroligin 1 0.088416
CNTLN centlein, centrosomal protein 0.088416
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.088384
LCK LCK proto-oncogene, Src family tyrosine kinase 0.088352
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.088319
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.088223
RAP2B RAP2B, member of RAS oncogene family 0.088158
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.088126
ARC activity-regulated cytoskeleton-associated protein 0.087344
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.087278
EDNRB endothelin receptor type B 0.087245
FGFR3 fibroblast growth factor receptor 3 0.087245
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.087212
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.086753
ARF3 ADP-ribosylation factor 3 0.08672
LY75 lymphocyte antigen 75 0.086622
MLXIPL MLX interacting protein-like 0.086524
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 0.086194
MSH2 mutS homolog 2 0.086194
WRN Werner syndrome, RecQ helicase-like 0.086094
MIR184 microRNA 184 0.086061
CNR1 cannabinoid receptor 1 (brain) 0.085961
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.085795
TBR1 T-box, brain, 1 0.085662
NOS1 nitric oxide synthase 1 (neuronal) 0.085495
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.085495
CNTN4 contactin 4 0.085395
XPO1 exportin 1 0.085229
RORC RAR-related orphan receptor C 0.085163
ANOS1 anosmin 1 0.08503
ITK IL2-inducible T-cell kinase 0.084863
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.084863
WWOX WW domain containing oxidoreductase 0.084863
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.084223
MITF microphthalmia-associated transcription factor 0.084021
FGFR2 fibroblast growth factor receptor 2 0.083987
COL1A2 collagen, type I, alpha 2 0.083718
DSCAM Down syndrome cell adhesion molecule 0.083684
RAE1 ribonucleic acid export 1 0.083684
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.082904
TAT tyrosine aminotransferase 0.082665
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.082665
NPAS2 neuronal PAS domain protein 2 0.082358
ANXA4 annexin A4 0.081571
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 0.081398
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.081398
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.081156
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.081122
TNS1 tensin 1 0.080742
PAX6 paired box 6 0.080707
ELAVL4 ELAV like neuron-specific RNA binding protein 4 0.080604
ADCY1 adenylate cyclase 1 (brain) 0.080156
HCK HCK proto-oncogene, Src family tyrosine kinase 0.079911
MAPK1 mitogen-activated protein kinase 1 0.079771
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.079562
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.079457
FGR FGR proto-oncogene, Src family tyrosine kinase 0.079317
NUMB numb homolog (Drosophila) 0.079317
BGN biglycan 0.079248
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.079178
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.079143
GJB2 gap junction protein, beta 2, 26kDa 0.079038
CCR4 chemokine (C-C motif) receptor 4 0.079038
COIL coilin 0.078969
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.078934
HLA-A major histocompatibility complex, class I, A 0.078794
EEF2 eukaryotic translation elongation factor 2 0.078725
CD24 CD24 molecule 0.078655
LATS1 large tumor suppressor kinase 1 0.07855
SAA1 serum amyloid A1 0.078197
TRIM32 tripartite motif containing 32 0.078056
MINK1 misshapen-like kinase 1 0.07788
GATA3 GATA binding protein 3 0.07781
SNORA29 small nucleolar RNA, H/ACA box 29 0.077493
STIM1 stromal interaction molecule 1 0.077387
GRIK1 glutamate receptor, ionotropic, kainate 1 0.077317
AURKAIP1 aurora kinase A interacting protein 1 0.077246
TGFBI transforming growth factor, beta-induced, 68kDa 0.077211
SYK spleen tyrosine kinase 0.077141
IGHV4-39 immunoglobulin heavy variable 4-39 0.077035
AGTR2 angiotensin II receptor, type 2 0.076716
TSC2 tuberous sclerosis 2 0.076644
SMN2 survival of motor neuron 2, centromeric 0.076538
PARG poly (ADP-ribose) glycohydrolase 0.076396
MBP myelin basic protein 0.076324
EGR1 early growth response 1 0.075934
H2AFX H2A histone family, member X 0.075792
APP amyloid beta (A4) precursor protein 0.075756
UBC ubiquitin C 0.075579
CD8B CD8b molecule 0.074936
DAD1 defender against cell death 1 0.074864
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.074864
RUNX2 runt-related transcription factor 2 0.074828
RPS27A ribosomal protein S27a 0.074756
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.074649