xamoterol-3064 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the xamoterol-3064 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABHD8 abhydrolase domain containing 8
ADAM22 ADAM metallopeptidase domain 22
ADH6 alcohol dehydrogenase 6 (class V)
ADRB1 adrenoceptor beta 1
AMACR alpha-methylacyl-CoA racemase
ARHGAP26 Rho GTPase activating protein 26
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
C11ORF80 chromosome 11 open reading frame 80
C16ORF45 chromosome 16 open reading frame 45
C7ORF26 chromosome 7 open reading frame 26
CD59 CD59 molecule, complement regulatory protein
CD68 CD68 molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCA1 chloride channel accessory 1
CLIC2 chloride intracellular channel 2
COL10A1 collagen, type X, alpha 1
COL6A1 collagen, type VI, alpha 1
CPN2 carboxypeptidase N, polypeptide 2
CREBBP CREB binding protein
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYB5R2 cytochrome b5 reductase 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAPK2 death-associated protein kinase 2
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DRD1 dopamine receptor D1
DUSP4 dual specificity phosphatase 4
EDDM3B epididymal protein 3B
EPO erythropoietin
EXT1 exostosin glycosyltransferase 1
FBXO40 F-box protein 40
FGFR3 fibroblast growth factor receptor 3
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GRIA3 glutamate receptor, ionotropic, AMPA 3
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HDGFRP3 hepatoma-derived growth factor, related protein 3
HESX1 HESX homeobox 1
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HOXB1 homeobox B1
HSPA12A heat shock 70kDa protein 12A
IFT22 intraflagellar transport 22
IL13 interleukin 13
INTS1 integrator complex subunit 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMC3 laminin, gamma 3
LOC57399 uncharacterized gastric protein ZA52P
LOC730101 uncharacterized LOC730101
MAGEC3 melanoma antigen family C3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPT microtubule-associated protein tau
MCAM melanoma cell adhesion molecule
MORC1 MORC family CW-type zinc finger 1
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MSX2 msh homeobox 2
NFIB nuclear factor I/B
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NHLH2 nescient helix loop helix 2
NKX3-2 NK3 homeobox 2
NNMT nicotinamide N-methyltransferase
NPR1 natriuretic peptide receptor 1
NPY neuropeptide Y
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PEX16 peroxisomal biogenesis factor 16
PKP2 plakophilin 2
PKP3 plakophilin 3
PLA2G16 phospholipase A2, group XVI
PMEPA1 prostate transmembrane protein, androgen induced 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRDM14 PR domain containing 14
PRO2964 uncharacterized protein PRO2964
PSG5 pregnancy specific beta-1-glycoprotein 5
QPCTL glutaminyl-peptide cyclotransferase-like
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RIMBP2 RIMS binding protein 2
RUFY3 RUN and FYVE domain containing 3
SAGE1 sarcoma antigen 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SIX3 SIX homeobox 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SRPX2 sushi-repeat containing protein, X-linked 2
TACR1 tachykinin receptor 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP2 TIMP metallopeptidase inhibitor 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRAPPC9 trafficking protein particle complex 9
TRIM10 tripartite motif containing 10
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TRO trophinin
ULBP1 UL16 binding protein 1
WNT8B wingless-type MMTV integration site family, member 8B
ZFHX3 zinc finger homeobox 3
ZNF362 zinc finger protein 362
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AIM2 absent in melanoma 2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARR3 arrestin 3, retinal (X-arrestin)
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC3 baculoviral IAP repeat containing 3
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF53 chromosome 17 open reading frame 53
C4BPA complement component 4 binding protein, alpha
C9ORF3 chromosome 9 open reading frame 3
CBX8 chromobox homolog 8
CCDC71 coiled-coil domain containing 71
CCRL2 chemokine (C-C motif) receptor-like 2
CD34 CD34 molecule
CDK20 cyclin-dependent kinase 20
CDY1 chromodomain protein, Y-linked, 1
CEP295 centrosomal protein 295kDa
CFAP69 cilia and flagella associated protein 69
CLIP2 CAP-GLY domain containing linker protein 2
CROT carnitine O-octanoyltransferase
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNAH17 dynein, axonemal, heavy chain 17
EMILIN2 elastin microfibril interfacer 2
FAM204A family with sequence similarity 204, member A
FDXR ferredoxin reductase
FKBP9 FK506 binding protein 9, 63 kDa
FOXN2 forkhead box N2
FOXO4 forkhead box O4
FRS3 fibroblast growth factor receptor substrate 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GZMK granzyme K (granzyme 3; tryptase II)
HDAC7 histone deacetylase 7
HIST1H1B histone cluster 1, H1b
HIST1H3H histone cluster 1, H3h
HOXB9 homeobox B9
HPCA hippocalcin
IBSP integrin-binding sialoprotein
INCENP inner centromere protein antigens 135/155kDa
KIF24 kinesin family member 24
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT8P12 keratin 8 pseudogene 12
LIG4 ligase IV, DNA, ATP-dependent
LIMD2 LIM domain containing 2
LOC100286895 cell division cycle 27 homolog pseudogene
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCPH1 microcephalin 1
MFSD11 major facilitator superfamily domain containing 11
MREG melanoregulin
MUC2 mucin 2, oligomeric mucus/gel-forming
MYO1E myosin IE
NNAT neuronatin
NOL10 nucleolar protein 10
NTN1 netrin 1
OXCT2 3-oxoacid CoA transferase 2
PADI1 peptidyl arginine deiminase, type I
PADI2 peptidyl arginine deiminase, type II
PDE12 phosphodiesterase 12
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX2 paired-like homeodomain 2
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRB3 proline-rich protein BstNI subfamily 3
PRICKLE3 prickle homolog 3 (Drosophila)
QSER1 glutamine and serine rich 1
SCG5 secretogranin V
SCYL2 SCY1-like 2 (S. cerevisiae)
SH3BGR SH3 domain binding glutamate-rich protein
SKA1 spindle and kinetochore associated complex subunit 1
SLAMF7 SLAM family member 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
STAP1 signal transducing adaptor family member 1
STRN striatin, calmodulin binding protein
SYNDIG1 synapse differentiation inducing 1
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
TLR4 toll-like receptor 4
TMEM53 transmembrane protein 53
TRPS1 trichorhinophalangeal syndrome I
TSC22D4 TSC22 domain family, member 4
TXLNG taxilin gamma
VN1R1 vomeronasal 1 receptor 1
YOD1 YOD1 deubiquitinase
ZNF10 zinc finger protein 10
ZNF16 zinc finger protein 16
ZNF354A zinc finger protein 354A
ZNF385D zinc finger protein 385D
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480
ZNF492 zinc finger protein 492
ZNF675 zinc finger protein 675