| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the xamoterol-3401 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTSL3 | ADAMTS-like 3 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ARTN | artemin |
| ATG10 | autophagy related 10 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC64 | coiled-coil domain containing 64 |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CD47 | CD47 molecule |
| CD52 | CD52 molecule |
| CDH8 | cadherin 8, type 2 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 |
| DEFB126 | defensin, beta 126 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNASE1 | deoxyribonuclease I |
| DOPEY2 | dopey family member 2 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FAM110B | family with sequence similarity 110, member B |
| FBXO21 | F-box protein 21 |
| FBXO4 | F-box protein 4 |
| FHL1 | four and a half LIM domains 1 |
| FMO5 | flavin containing monooxygenase 5 |
| FOXG1 | forkhead box G1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLP1R | glucagon-like peptide 1 receptor |
| GM2A | GM2 ganglioside activator |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTMR3 | myotubularin related protein 3 |
| MX1 | MX dynamin-like GTPase 1 |
| NIPAL3 | NIPA-like domain containing 3 |
| NPR1 | natriuretic peptide receptor 1 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| NUP214 | nucleoporin 214kDa |
| PADI3 | peptidyl arginine deiminase, type III |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDE9A | phosphodiesterase 9A |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PHTF2 | putative homeodomain transcription factor 2 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PQLC2 | PQ loop repeat containing 2 |
| PRDX2 | peroxiredoxin 2 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RNF39 | ring finger protein 39 |
| RUNX1 | runt-related transcription factor 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SFTPB | surfactant protein B |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SRRT | serrate, RNA effector molecule |
| STS | steroid sulfatase (microsomal), isozyme S |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYNDIG1 | synapse differentiation inducing 1 |
| T | T, brachyury homolog (mouse) |
| TBX6 | T-box 6 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMOD1 | tropomodulin 1 |
| TMOD2 | tropomodulin 2 (neuronal) |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZNF343 | zinc finger protein 343 |
| ZNF362 | zinc finger protein 362 |
| ZNF384 | zinc finger protein 384 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTL8 | actin-like 8 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CNTNAP1 | contactin associated protein 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DBF4B | DBF4 zinc finger B |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DOK5 | docking protein 5 |
| DUSP13 | dual specificity phosphatase 13 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM204A | family with sequence similarity 204, member A |
| FAM212B | family with sequence similarity 212, member B |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAST | gastrin |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GLRA1 | glycine receptor, alpha 1 |
| GMPR | guanosine monophosphate reductase |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4E | histone cluster 1, H4e |
| HYAL1 | hyaluronoglucosaminidase 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITM2C | integral membrane protein 2C |
| KDM8 | lysine (K)-specific demethylase 8 |
| KRT83 | keratin 83, type II |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC729164 | hCG1732469 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MSI1 | musashi RNA-binding protein 1 |
| NKX3-2 | NK3 homeobox 2 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OCLM | oculomedin |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIGR | polymeric immunoglobulin receptor |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLXNB3 | plexin B3 |
| PODNL1 | podocan-like 1 |
| PODXL2 | podocalyxin-like 2 |
| PRAMEF11 | PRAME family member 11 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| RNF43 | ring finger protein 43 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| S100A9 | S100 calcium binding protein A9 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRR2B | small proline-rich protein 2B |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STMN3 | stathmin-like 3 |
| SYNC | syncoilin, intermediate filament protein |
| TBX19 | T-box 19 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGFBR3 | transforming growth factor, beta receptor III |
| THBS3 | thrombospondin 3 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM254 | transmembrane protein 254 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VEGFB | vascular endothelial growth factor B |
| WDR62 | WD repeat domain 62 |
| WDR78 | WD repeat domain 78 |
| XDH | xanthine dehydrogenase |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF10 | zinc finger protein 10 |
| ZNF136 | zinc finger protein 136 |