xamoterol-5363 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the xamoterol-5363 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACVR1B activin A receptor, type IB
ADCY6 adenylate cyclase 6
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BAX BCL2-associated X protein
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C17ORF80 chromosome 17 open reading frame 80
C21ORF2 chromosome 21 open reading frame 2
CD22 CD22 molecule
CD47 CD47 molecule
CDKL3 cyclin-dependent kinase-like 3
CLN3 ceroid-lipofuscinosis, neuronal 3
CNR2 cannabinoid receptor 2 (macrophage)
COBLL1 cordon-bleu WH2 repeat protein-like 1
CTNS cystinosin, lysosomal cystine transporter
CUL2 cullin 2
DCAF13 DDB1 and CUL4 associated factor 13
EHD2 EH-domain containing 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBXO38 F-box protein 38
FGFR1 fibroblast growth factor receptor 1
FKBP10 FK506 binding protein 10, 65 kDa
FLII flightless I homolog (Drosophila)
FRK fyn-related Src family tyrosine kinase
FUS FUS RNA binding protein
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GBAS glioblastoma amplified sequence
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
H2AFX H2A histone family, member X
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HSPB11 heat shock protein family B (small), member 11
IDI2-AS1 IDI2 antisense RNA 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
LAMC2 laminin, gamma 2
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP4 microtubule-associated protein 4
MAP7D3 MAP7 domain containing 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSI1 musashi RNA-binding protein 1
MTA1 metastasis associated 1
NAV2 neuron navigator 2
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NMT1 N-myristoyltransferase 1
NOS1 nitric oxide synthase 1 (neuronal)
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
PC pyruvate carboxylase
PCGF2 polycomb group ring finger 2
PDIA4 protein disulfide isomerase family A, member 4
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX26 peroxisomal biogenesis factor 26
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POT1 protection of telomeres 1
PP14571 uncharacterized LOC100130449
PPP6R2 protein phosphatase 6, regulatory subunit 2
PVT1 Pvt1 oncogene (non-protein coding)
RAD50 RAD50 homolog (S. cerevisiae)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RECQL5 RecQ protein-like 5
RGS19 regulator of G-protein signaling 19
RPL13P5 ribosomal protein L13 pseudogene 5
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SH3BP2 SH3-domain binding protein 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SND1-IT1 SND1 intronic transcript 1
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOX4 SRY (sex determining region Y)-box 4
STX1A syntaxin 1A (brain)
TAGLN transgelin
TLDC1 TBC/LysM-associated domain containing 1
TPD52 tumor protein D52
TRAK1 trafficking protein, kinesin binding 1
TRIM25 tripartite motif containing 25
TTLL3 tubulin tyrosine ligase-like family member 3
ZBTB48 zinc finger and BTB domain containing 48
ZNF552 zinc finger protein 552
ZNF589 zinc finger protein 589
ZNF609 zinc finger protein 609
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AXIN1 axin 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRPF1 bromodomain and PHD finger containing, 1
BTF3P11 basic transcription factor 3 pseudogene 11
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAPG capping protein (actin filament), gelsolin-like
CDK20 cyclin-dependent kinase 20
CEP97 centrosomal protein 97kDa
CLDN4 claudin 4
CNGB3 cyclic nucleotide gated channel beta 3
CORO2A coronin, actin binding protein, 2A
CPPED1 calcineurin-like phosphoesterase domain containing 1
CUL9 cullin 9
DCAF10 DDB1 and CUL4 associated factor 10
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DET1 de-etiolated homolog 1 (Arabidopsis)
DGKD diacylglycerol kinase, delta 130kDa
ECHDC3 enoyl CoA hydratase domain containing 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ERCC4 excision repair cross-complementation group 4
FAM222B family with sequence similarity 222, member B
FANCC Fanconi anemia, complementation group C
FASTKD5 FAST kinase domains 5
FBRS fibrosin
FBXO34 F-box protein 34
FHOD1 formin homology 2 domain containing 1
GID4 GID complex subunit 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GRWD1 glutamate-rich WD repeat containing 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTPBP2 GTP binding protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BO histone cluster 1, H2bo
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HP1BP3 heterochromatin protein 1, binding protein 3
INF2 inverted formin, FH2 and WH2 domain containing
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IRAK4 interleukin-1 receptor-associated kinase 4
JADE3 jade family PHD finger 3
LOC100287590 uncharacterized LOC100287590
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MICALL2 MICAL-like 2
MITF microphthalmia-associated transcription factor
MPI mannose phosphate isomerase
MRPL44 mitochondrial ribosomal protein L44
MTMR6 myotubularin related protein 6
MXD3 MAX dimerization protein 3
NABP2 nucleic acid binding protein 2
NDE1 nudE neurodevelopment protein 1
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
PARPBP PARP1 binding protein
PCDHA9 protocadherin alpha 9
PCSK7 proprotein convertase subtilisin/kexin type 7
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPAN peter pan homolog (Drosophila)
PVRL3 poliovirus receptor-related 3
PYCRL pyrroline-5-carboxylate reductase-like
PYGB phosphorylase, glycogen; brain
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RIBC2 RIB43A domain with coiled-coils 2
RNF123 ring finger protein 123
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SETD1A SET domain containing 1A
SIRAL2 SIR2 antiphage like 2
SKIL SKI-like proto-oncogene
SLC22A18 solute carrier family 22, member 18
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SSBP3 single stranded DNA binding protein 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TRAIP TRAF interacting protein
TRIM16 tripartite motif containing 16
TTBK2 tau tubulin kinase 2
TWSG1 twisted gastrulation BMP signaling modulator 1
WDR91 WD repeat domain 91
ZNF134 zinc finger protein 134
ZNF212 zinc finger protein 212
ZNF254 zinc finger protein 254
ZNF639 zinc finger protein 639
ZNF652 zinc finger protein 652
ZNF696 zinc finger protein 696
ZNF768 zinc finger protein 768