ximelagatran Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted to the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage. (Chemical Entities of Biological Interest Ontology, CHEBI_65172)
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Genes

3 genes co-occuring with the biological term ximelagatran in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)