| Dataset | Guide to Pharmacology Chemical Ligands of Receptors |
| Category | physical interactions |
| Type | ligand (chemical) |
| Description | A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted to the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage. (Chemical Entities of Biological Interest Ontology, CHEBI_65172) |
| External Link | http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6381 |
| Similar Terms | |
| Downloads & Tools |
1 receptors of the ximelagatran ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.
| Symbol | Name |
|---|---|
| F2 | coagulation factor II (thrombin) |
