| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the xylazine-2132 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ACO2 | aconitase 2, mitochondrial |
| ACRV1 | acrosomal vesicle protein 1 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADRA1A | adrenoceptor alpha 1A |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANK1 | ankyrin 1, erythrocytic |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| BDKRB1 | bradykinin receptor B1 |
| C18ORF25 | chromosome 18 open reading frame 25 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CAPN9 | calpain 9 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC57 | coiled-coil domain containing 57 |
| CCDC64 | coiled-coil domain containing 64 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK20 | cyclin-dependent kinase 20 |
| CELP | carboxyl ester lipase pseudogene |
| COL18A1 | collagen, type XVIII, alpha 1 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| EDA | ectodysplasin A |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| EPHA5 | EPH receptor A5 |
| EPS8L1 | EPS8-like 1 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GCFC2 | GC-rich sequence DNA-binding factor 2 |
| GK2 | glycerol kinase 2 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPR19 | G protein-coupled receptor 19 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GYG2 | glycogenin 2 |
| H2AFX | H2A histone family, member X |
| HOXA3 | homeobox A3 |
| IL27RA | interleukin 27 receptor, alpha |
| JAM2 | junctional adhesion molecule 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCTD2 | potassium channel tetramerization domain containing 2 |
| KHK | ketohexokinase (fructokinase) |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| LRRC16A | leucine rich repeat containing 16A |
| MAPK11 | mitogen-activated protein kinase 11 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCAM | melanoma cell adhesion molecule |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MEF2C | myocyte enhancer factor 2C |
| MINK1 | misshapen-like kinase 1 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MTA2 | metastasis associated 1 family, member 2 |
| MYH15 | myosin, heavy chain 15 |
| NEB | nebulin |
| NEK9 | NIMA-related kinase 9 |
| NF2 | neurofibromin 2 (merlin) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PLK3 | polo-like kinase 3 |
| POPDC2 | popeye domain containing 2 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PTCRA | pre T-cell antigen receptor alpha |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RECQL5 | RecQ protein-like 5 |
| RUNDC3B | RUN domain containing 3B |
| RYR1 | ryanodine receptor 1 (skeletal) |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIRPB1 | signal-regulatory protein beta 1 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| STRA6 | stimulated by retinoic acid 6 |
| TK2 | thymidine kinase 2, mitochondrial |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBOX5 | U-box domain containing 5 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| ZNF135 | zinc finger protein 135 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ARMC7 | armadillo repeat containing 7 |
| ASPN | asporin |
| AXIN1 | axin 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C3 | complement component 3 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CEP97 | centrosomal protein 97kDa |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CHM | choroideremia (Rab escort protein 1) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DDRGK1 | DDRGK domain containing 1 |
| DENND5B | DENN/MADD domain containing 5B |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNMBP | dynamin binding protein |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| EFNA3 | ephrin-A3 |
| EGR2 | early growth response 2 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FHL3 | four and a half LIM domains 3 |
| FJX1 | four jointed box 1 (Drosophila) |
| FMNL1 | formin-like 1 |
| FOSL1 | FOS-like antigen 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GCH1 | GTP cyclohydrolase 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRAMD1B | GRAM domain containing 1B |
| GSDMD | gasdermin D |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA5 | homeobox A5 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| JMJD4 | jumonji domain containing 4 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA1024 | KIAA1024 |
| KLHL28 | kelch-like family member 28 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MARCKSL1 | MARCKS-like 1 |
| METRN | meteorin, glial cell differentiation regulator |
| MYL5 | myosin, light chain 5, regulatory |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PGP | phosphoglycolate phosphatase |
| PHACTR1 | phosphatase and actin regulator 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PITX2 | paired-like homeodomain 2 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| POR | P450 (cytochrome) oxidoreductase |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTDSS2 | phosphatidylserine synthase 2 |
| RANBP17 | RAN binding protein 17 |
| RGS13 | regulator of G-protein signaling 13 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHOH | ras homolog family member H |
| RNF121 | ring finger protein 121 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPA4 | replication protein A4, 30kDa |
| RPAP2 | RNA polymerase II associated protein 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SPATA7 | spermatogenesis associated 7 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STBD1 | starch binding domain 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TASP1 | taspase, threonine aspartase, 1 |
| TMEM212 | transmembrane protein 212 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TNRC6B | trinucleotide repeat containing 6B |
| TTC23 | tetratricopeptide repeat domain 23 |
| USB1 | U6 snRNA biogenesis 1 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF254 | zinc finger protein 254 |
| ZNF354A | zinc finger protein 354A |