xylazine-2788 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the xylazine-2788 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACTL8 actin-like 8
AJAP1 adherens junctions associated protein 1
ANK1 ankyrin 1, erythrocytic
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ART1 ADP-ribosyltransferase 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATAT1 alpha tubulin acetyltransferase 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAS1 breast carcinoma amplified sequence 1
BRS3 bombesin-like receptor 3
BTG2 BTG family, member 2
CABIN1 calcineurin binding protein 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CD101 CD101 molecule
CD34 CD34 molecule
CLTA clathrin, light chain A
CPTP ceramide-1-phosphate transfer protein
CUL3 cullin 3
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLL3 delta-like 3 (Drosophila)
DMTN dematin actin binding protein
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPF3 D4, zinc and double PHD fingers, family 3
EDA ectodysplasin A
EFR3B EFR3 homolog B (S. cerevisiae)
ELOVL2 ELOVL fatty acid elongase 2
EMC1 ER membrane protein complex subunit 1
FAT2 FAT atypical cadherin 2
GAB1 GRB2-associated binding protein 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GDF5 growth differentiation factor 5
GFER growth factor, augmenter of liver regeneration
GHRHR growth hormone releasing hormone receptor
GNRH2 gonadotropin-releasing hormone 2
GREB1L growth regulation by estrogen in breast cancer-like
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HFE hemochromatosis
HSF2BP heat shock transcription factor 2 binding protein
ICOSLG inducible T-cell co-stimulator ligand
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA1324 KIAA1324
KLK8 kallikrein-related peptidase 8
LAMB3 laminin, beta 3
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOC157562 uncharacterized LOC157562
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA5 melanoma antigen family A5
MLN motilin
MMP3 matrix metallopeptidase 3
MST1 macrophage stimulating 1
MST1L macrophage stimulating 1-like
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYL10 myosin, light chain 10, regulatory
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NELL2 NEL-like 2 (chicken)
OR1F1 olfactory receptor, family 1, subfamily F, member 1
PADI1 peptidyl arginine deiminase, type I
PCDH11Y protocadherin 11 Y-linked
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLLP plasmolipin
PRAMEF11 PRAME family member 11
PRM1 protamine 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PVR poliovirus receptor
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBMS2 RNA binding motif, single stranded interacting protein 2
RETN resistin
RNF39 ring finger protein 39
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPL35A ribosomal protein L35a
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAFB scaffold attachment factor B
SGK2 serum/glucocorticoid regulated kinase 2
SH3BP2 SH3-domain binding protein 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SKI SKI proto-oncogene
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SSX1 synovial sarcoma, X breakpoint 1
TAOK2 TAO kinase 2
TBX19 T-box 19
TGM2 transglutaminase 2
TJAP1 tight junction associated protein 1 (peripheral)
TLR1 toll-like receptor 1
TMEM144 transmembrane protein 144
TSC22D4 TSC22 domain family, member 4
VIM vimentin
ZBTB20 zinc finger and BTB domain containing 20
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AFAP1 actin filament associated protein 1
ASAP1-IT1 ASAP1 intronic transcript 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXIN1 axin 1
C16ORF59 chromosome 16 open reading frame 59
C5 complement component 5
C7ORF43 chromosome 7 open reading frame 43
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPN15 calpain 15
CBR1 carbonyl reductase 1
CCDC109B coiled-coil domain containing 109B
CENPO centromere protein O
CHMP6 charged multivesicular body protein 6
CLCN5 chloride channel, voltage-sensitive 5
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DEAF1 DEAF1 transcription factor
DENND1B DENN/MADD domain containing 1B
DNAL4 dynein, axonemal, light chain 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM188A family with sequence similarity 188, member A
FBXO31 F-box protein 31
FER fer (fps/fes related) tyrosine kinase
FGD6 FYVE, RhoGEF and PH domain containing 6
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAMT guanidinoacetate N-methyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPATCH2L G patch domain containing 2-like
GPR87 G protein-coupled receptor 87
HIST1H4D histone cluster 1, H4d
HPS4 Hermansky-Pudlak syndrome 4
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFT22 intraflagellar transport 22
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIAA0355 KIAA0355
LIG4 ligase IV, DNA, ATP-dependent
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK3 mitogen-activated protein kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MMP9 matrix metallopeptidase 9
MOSPD3 motile sperm domain containing 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTCP1 mature T-cell proliferation 1
MXD3 MAX dimerization protein 3
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO9A myosin IXA
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OLFML3 olfactomedin-like 3
PCDHA6 protocadherin alpha 6
PES1 pescadillo ribosomal biogenesis factor 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM42 RNA binding motif protein 42
RFTN1 raftlin, lipid raft linker 1
RNF121 ring finger protein 121
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SAYSD1 SAYSVFN motif domain containing 1
SCRN3 secernin 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
STK16 serine/threonine kinase 16
STRN striatin, calmodulin binding protein
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYCP2 synaptonemal complex protein 2
TESC tescalcin
TGFB3 transforming growth factor, beta 3
TMEM11 transmembrane protein 11
TMEM254 transmembrane protein 254
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TSPAN1 tetraspanin 1
UBXN8 UBX domain protein 8
UFSP2 UFM1-specific peptidase 2
UNC13B unc-13 homolog B (C. elegans)
WDR76 WD repeat domain 76
ZBED1 zinc finger, BED-type containing 1
ZBTB10 zinc finger and BTB domain containing 10
ZBTB3 zinc finger and BTB domain containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMAT5 zinc finger, matrin-type 5
ZNF329 zinc finger protein 329
ZNF480 zinc finger protein 480
ZNF639 zinc finger protein 639