| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the xylazine-2788 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACTL8 | actin-like 8 |
| AJAP1 | adherens junctions associated protein 1 |
| ANK1 | ankyrin 1, erythrocytic |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ART1 | ADP-ribosyltransferase 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BRS3 | bombesin-like receptor 3 |
| BTG2 | BTG family, member 2 |
| CABIN1 | calcineurin binding protein 1 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CD101 | CD101 molecule |
| CD34 | CD34 molecule |
| CLTA | clathrin, light chain A |
| CPTP | ceramide-1-phosphate transfer protein |
| CUL3 | cullin 3 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DLL3 | delta-like 3 (Drosophila) |
| DMTN | dematin actin binding protein |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EDA | ectodysplasin A |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EMC1 | ER membrane protein complex subunit 1 |
| FAT2 | FAT atypical cadherin 2 |
| GAB1 | GRB2-associated binding protein 1 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GDF5 | growth differentiation factor 5 |
| GFER | growth factor, augmenter of liver regeneration |
| GHRHR | growth hormone releasing hormone receptor |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HFE | hemochromatosis |
| HSF2BP | heat shock transcription factor 2 binding protein |
| ICOSLG | inducible T-cell co-stimulator ligand |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA1324 | KIAA1324 |
| KLK8 | kallikrein-related peptidase 8 |
| LAMB3 | laminin, beta 3 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LOC157562 | uncharacterized LOC157562 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA5 | melanoma antigen family A5 |
| MLN | motilin |
| MMP3 | matrix metallopeptidase 3 |
| MST1 | macrophage stimulating 1 |
| MST1L | macrophage stimulating 1-like |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| MYL10 | myosin, light chain 10, regulatory |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NELL2 | NEL-like 2 (chicken) |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDH11Y | protocadherin 11 Y-linked |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLLP | plasmolipin |
| PRAMEF11 | PRAME family member 11 |
| PRM1 | protamine 1 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| PVR | poliovirus receptor |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RETN | resistin |
| RNF39 | ring finger protein 39 |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase |
| RPL35A | ribosomal protein L35a |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SAFB | scaffold attachment factor B |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SKI | SKI proto-oncogene |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| TAOK2 | TAO kinase 2 |
| TBX19 | T-box 19 |
| TGM2 | transglutaminase 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLR1 | toll-like receptor 1 |
| TMEM144 | transmembrane protein 144 |
| TSC22D4 | TSC22 domain family, member 4 |
| VIM | vimentin |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| AFAP1 | actin filament associated protein 1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| AXIN1 | axin 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAPN15 | calpain 15 |
| CBR1 | carbonyl reductase 1 |
| CCDC109B | coiled-coil domain containing 109B |
| CENPO | centromere protein O |
| CHMP6 | charged multivesicular body protein 6 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DEAF1 | DEAF1 transcription factor |
| DENND1B | DENN/MADD domain containing 1B |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFNA3 | ephrin-A3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM188A | family with sequence similarity 188, member A |
| FBXO31 | F-box protein 31 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPATCH2L | G patch domain containing 2-like |
| GPR87 | G protein-coupled receptor 87 |
| HIST1H4D | histone cluster 1, H4d |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFT22 | intraflagellar transport 22 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KIAA0355 | KIAA0355 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MMP9 | matrix metallopeptidase 9 |
| MOSPD3 | motile sperm domain containing 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTCP1 | mature T-cell proliferation 1 |
| MXD3 | MAX dimerization protein 3 |
| MYH9 | myosin, heavy chain 9, non-muscle |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYO9A | myosin IXA |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| OLFML3 | olfactomedin-like 3 |
| PCDHA6 | protocadherin alpha 6 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RBM42 | RNA binding motif protein 42 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF121 | ring finger protein 121 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCRN3 | secernin 3 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP1 | Sp1 transcription factor |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STK16 | serine/threonine kinase 16 |
| STRN | striatin, calmodulin binding protein |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TESC | tescalcin |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM11 | transmembrane protein 11 |
| TMEM254 | transmembrane protein 254 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TSPAN1 | tetraspanin 1 |
| UBXN8 | UBX domain protein 8 |
| UFSP2 | UFM1-specific peptidase 2 |
| UNC13B | unc-13 homolog B (C. elegans) |
| WDR76 | WD repeat domain 76 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF329 | zinc finger protein 329 |
| ZNF480 | zinc finger protein 480 |
| ZNF639 | zinc finger protein 639 |