| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the xylazine-4066 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| AFF3 | AF4/FMR2 family, member 3 |
| AIF1 | allograft inflammatory factor 1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APP | amyloid beta (A4) precursor protein |
| AR | androgen receptor |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARMC4 | armadillo repeat containing 4 |
| ATP9B | ATPase, class II, type 9B |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BBC3 | BCL2 binding component 3 |
| BMP4 | bone morphogenetic protein 4 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACFD1 | calcium channel flower domain containing 1 |
| CD200 | CD200 molecule |
| CD6 | CD6 molecule |
| CD80 | CD80 molecule |
| CES3 | carboxylesterase 3 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CREBBP | CREB binding protein |
| CSF1R | colony stimulating factor 1 receptor |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DENND1C | DENN/MADD domain containing 1C |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIAPH1 | diaphanous-related formin 1 |
| DKFZP434C153 | DKFZP434C153 protein |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DSG3 | desmoglein 3 |
| EMC3 | ER membrane protein complex subunit 3 |
| FASN | fatty acid synthase |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FGF16 | fibroblast growth factor 16 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GLB1L | galactosidase, beta 1-like |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GRM7 | glutamate receptor, metabotropic 7 |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| IL1RN | interleukin 1 receptor antagonist |
| ING4 | inhibitor of growth family, member 4 |
| INO80B | INO80 complex subunit B |
| KLHL11 | kelch-like family member 11 |
| KLHL4 | kelch-like family member 4 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYF5 | myogenic factor 5 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NF1 | neurofibromin 1 |
| NKX2-1 | NK2 homeobox 1 |
| PAPPA2 | pappalysin 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIPOX | pipecolic acid oxidase |
| PLCD1 | phospholipase C, delta 1 |
| POU3F2 | POU class 3 homeobox 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRLH | prolactin releasing hormone |
| PRX | periaxin |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAP2B | RAP2B, member of RAS oncogene family |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RPS14 | ribosomal protein S14 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SIRAL2 | SIR2 antiphage like 2 |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAGLN3 | transgelin 3 |
| TAOK2 | TAO kinase 2 |
| TBX1 | T-box 1 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP53 | tumor protein p53 |
| TPP1 | tripeptidyl peptidase I |
| TPSAB1 | tryptase alpha/beta 1 |
| TSC2 | tuberous sclerosis 2 |
| TSPAN8 | tetraspanin 8 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZNF334 | zinc finger protein 334 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACE | angiotensin I converting enzyme |
| ADAM2 | ADAM metallopeptidase domain 2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ASTN1 | astrotactin 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C3AR1 | complement component 3a receptor 1 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CASS4 | Cas scaffolding protein family member 4 |
| CCDC102B | coiled-coil domain containing 102B |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CDIP1 | cell death-inducing p53 target 1 |
| CES1 | carboxylesterase 1 |
| CFH | complement factor H |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNN1 | calponin 1, basic, smooth muscle |
| CORO2B | coronin, actin binding protein, 2B |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPNE7 | copine VII |
| CREB5 | cAMP responsive element binding protein 5 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DIO3 | deiodinase, iodothyronine, type III |
| DLK2 | delta-like 2 homolog (Drosophila) |
| EGR2 | early growth response 2 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM120C | family with sequence similarity 120C |
| FBXO31 | F-box protein 31 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AK | histone cluster 1, H2ak |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| INO80D | INO80 complex subunit D |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0894 | KIAA0894 protein |
| KIFC3 | kinesin family member C3 |
| LENEP | lens epithelial protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC100129648 | uncharacterized LOC100129648 |
| LRRC2 | leucine rich repeat containing 2 |
| LTC4S | leukotriene C4 synthase |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP6D1 | MAP6 domain containing 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MGP | matrix Gla protein |
| MMP9 | matrix metallopeptidase 9 |
| MRAS | muscle RAS oncogene homolog |
| MTCP1 | mature T-cell proliferation 1 |
| MUC3A | mucin 3A, cell surface associated |
| MYOZ3 | myozenin 3 |
| NNAT | neuronatin |
| NOL4 | nucleolar protein 4 |
| NPPB | natriuretic peptide B |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OSMR | oncostatin M receptor |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLXNB3 | plexin B3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODXL2 | podocalyxin-like 2 |
| RAPSN | receptor-associated protein of the synapse |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SIX3 | SIX homeobox 3 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TBKBP1 | TBK1 binding protein 1 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNRC6B | trinucleotide repeat containing 6B |
| TPCN1 | two pore segment channel 1 |
| TRAC | T cell receptor alpha constant |
| URGCP | upregulator of cell proliferation |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF222 | zinc finger protein 222 |
| ZNF268 | zinc finger protein 268 |
| ZNF529 | zinc finger protein 529 |
| ZNF862 | zinc finger protein 862 |
