| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the xylazine-4147 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARG1 | arginase 1 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ASMT | acetylserotonin O-methyltransferase |
| ATP10B | ATPase, class V, type 10B |
| C22ORF24 | chromosome 22 open reading frame 24 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD209 | CD209 molecule |
| CD5 | CD5 molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| COL13A1 | collagen, type XIII, alpha 1 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor |
| CST8 | cystatin 8 (cystatin-related epididymal specific) |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DAPK1 | death-associated protein kinase 1 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLJ11292 | |
| FST | follistatin |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GGT1 | gamma-glutamyltransferase 1 |
| GLB1L | galactosidase, beta 1-like |
| HAL | histidine ammonia-lyase |
| HFE | hemochromatosis |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOXB5 | homeobox B5 |
| HOXB6 | homeobox B6 |
| HOXC4 | homeobox C4 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL1RN | interleukin 1 receptor antagonist |
| IL2RB | interleukin 2 receptor, beta |
| INSL4 | insulin-like 4 (placenta) |
| JAM3 | junctional adhesion molecule 3 |
| KIF21B | kinesin family member 21B |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KRT2 | keratin 2, type II |
| KRT38 | keratin 38, type I |
| LAMB4 | laminin, beta 4 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LOC100131510 | uncharacterized LOC100131510 |
| LOXL2 | lysyl oxidase-like 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MINK1 | misshapen-like kinase 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMP11 | matrix metallopeptidase 11 |
| MUC8 | mucin 8 |
| MYOZ3 | myozenin 3 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NNAT | neuronatin |
| NOV | nephroblastoma overexpressed |
| NPAS3 | neuronal PAS domain protein 3 |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) |
| NRL | neural retina leucine zipper |
| OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
| OR2C1 | olfactory receptor, family 2, subfamily C, member 1 |
| PAX8 | paired box 8 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PRDM14 | PR domain containing 14 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| RANBP3 | RAN binding protein 3 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RORA | RAR-related orphan receptor A |
| SAMD4B | sterile alpha motif domain containing 4B |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC39A9 | solute carrier family 39, member 9 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPEG | SPEG complex locus |
| SPON1 | spondin 1, extracellular matrix protein |
| STS | steroid sulfatase (microsomal), isozyme S |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TAGLN3 | transgelin 3 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TLR1 | toll-like receptor 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRBC1 | T cell receptor beta constant 1 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ASNSD1 | asparagine synthetase domain containing 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| AUP1 | ancient ubiquitous protein 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CALML5 | calmodulin-like 5 |
| CAPN15 | calpain 15 |
| CCNE1 | cyclin E1 |
| CD83 | CD83 molecule |
| CD8A | CD8a molecule |
| CDHR2 | cadherin-related family member 2 |
| CHKB | choline kinase beta |
| CIC | capicua transcriptional repressor |
| CLDN1 | claudin 1 |
| CORO7 | coronin 7 |
| CPB2 | carboxypeptidase B2 (plasma) |
| DBF4B | DBF4 zinc finger B |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FAM76A | family with sequence similarity 76, member A |
| FBXO2 | F-box protein 2 |
| FBXO31 | F-box protein 31 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ22184 | |
| FOXD1 | forkhead box D1 |
| HDAC4 | histone deacetylase 4 |
| HIST1H1D | histone cluster 1, H1d |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL22 | interleukin 22 |
| JUNB | jun B proto-oncogene |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LHX1 | LIM homeobox 1 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MDM4 | MDM4, p53 regulator |
| MED31 | mediator complex subunit 31 |
| MEFV | Mediterranean fever |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOB3B | MOB kinase activator 3B |
| MST1 | macrophage stimulating 1 |
| MUC3A | mucin 3A, cell surface associated |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB5B | RAB5B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RFPL1S | RFPL1 antisense RNA 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RND1 | Rho family GTPase 1 |
| RNF208 | ring finger protein 208 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SNX15 | sorting nexin 15 |
| SP1 | Sp1 transcription factor |
| TCP10 | t-complex 10 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TLR2 | toll-like receptor 2 |
| TOR4A | torsin family 4, member A |
| TRAIP | TRAF interacting protein |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VASH2 | vasohibin 2 |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF324 | zinc finger protein 324 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF551 | zinc finger protein 551 |
| ZNF862 | zinc finger protein 862 |
| ZW10 | zw10 kinetochore protein |