xylometazoline-1423 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the xylometazoline-1423 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AGRN agrin
AKAP11 A kinase (PRKA) anchor protein 11
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APH1A APH1A gamma secretase subunit
APOC1 apolipoprotein C-I
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ART1 ADP-ribosyltransferase 1
ATG2A autophagy related 2A
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BMP2K BMP2 inducible kinase
CA14 carbonic anhydrase XIV
CADM3 cell adhesion molecule 3
CAPRIN2 caprin family member 2
CCHCR1 coiled-coil alpha-helical rod protein 1
CD84 CD84 molecule
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CREM cAMP responsive element modulator
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRMP1 collapsin response mediator protein 1
CTSZ cathepsin Z
DCAF15 DDB1 and CUL4 associated factor 15
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
E2F4 E2F transcription factor 4, p107/p130-binding
ELMO2 engulfment and cell motility 2
EPHB2 EPH receptor B2
ETV7 ets variant 7
FAM102A family with sequence similarity 102, member A
FAM134B family with sequence similarity 134, member B
FBXO31 F-box protein 31
FBXO42 F-box protein 42
FEM1B fem-1 homolog b (C. elegans)
FGFR1 fibroblast growth factor receptor 1
FLCN folliculin
FNBP1 formin binding protein 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAA glucosidase, alpha; acid
GIMAP5 GTPase, IMAP family member 5
GJB3 gap junction protein, beta 3, 31kDa
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GOLGA1 golgin A1
GON4L gon-4-like (C. elegans)
HBB hemoglobin, beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNF1A HNF1 homeobox A
HNRNPL heterogeneous nuclear ribonucleoprotein L
HTRA2 HtrA serine peptidase 2
IL18BP interleukin 18 binding protein
INHBC inhibin, beta C
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAG1 jagged 1
JRK Jrk homolog (mouse)
KAT8 K(lysine) acetyltransferase 8
KDM2A lysine (K)-specific demethylase 2A
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOXL3 lysyl oxidase-like 3
LPP LIM domain containing preferred translocation partner in lipoma
MAN1B1 mannosidase, alpha, class 1B, member 1
MAP2K5 mitogen-activated protein kinase kinase 5
MVP major vault protein
NARFL nuclear prelamin A recognition factor-like
NAT6 N-acetyltransferase 6 (GCN5-related)
NCAPH2 non-SMC condensin II complex, subunit H2
NCR2 natural cytotoxicity triggering receptor 2
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OCRL oculocerebrorenal syndrome of Lowe
PADI1 peptidyl arginine deiminase, type I
PAQR6 progestin and adipoQ receptor family member VI
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G15 phospholipase A2, group XV
PLD2 phospholipase D2
PLEK2 pleckstrin 2
PTPRU protein tyrosine phosphatase, receptor type, U
RBM12B RNA binding motif protein 12B
RECQL4 RecQ protein-like 4
RORC RAR-related orphan receptor C
RPAIN RPA interacting protein
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SALL2 spalt-like transcription factor 2
SERBP1 SERPINE1 mRNA binding protein 1
SFTPC surfactant protein C
SMAD3 SMAD family member 3
SPIDR scaffolding protein involved in DNA repair
SPN sialophorin
SRSF7 serine/arginine-rich splicing factor 7
SSTR4 somatostatin receptor 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TRIM29 tripartite motif containing 29
TRPM3 transient receptor potential cation channel, subfamily M, member 3
UBOX5 U-box domain containing 5
WDTC1 WD and tetratricopeptide repeats 1
ZC3H12A zinc finger CCCH-type containing 12A
ZC4H2 zinc finger, C4H2 domain containing
ZMAT3 zinc finger, matrin-type 3
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACVR1 activin A receptor, type I
ADAM9 ADAM metallopeptidase domain 9
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APIP APAF1 interacting protein
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AXIN1 axin 1
BRIX1 BRX1, biogenesis of ribosomes
CASZ1 castor zinc finger 1
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CD151 CD151 molecule (Raph blood group)
CLTCL1 clathrin, heavy chain-like 1
COMMD10 COMM domain containing 10
CRY1 cryptochrome circadian clock 1
CTPS1 CTP synthase 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCK deoxycytidine kinase
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND4A DENN/MADD domain containing 4A
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ECT2 epithelial cell transforming 2
ELP3 elongator acetyltransferase complex subunit 3
FAM3C family with sequence similarity 3, member C
FAM57A family with sequence similarity 57, member A
FANCL Fanconi anemia, complementation group L
FCHO1 FCH domain only 1
FUBP3 far upstream element (FUSE) binding protein 3
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GIMAP6 GTPase, IMAP family member 6
GPR183 G protein-coupled receptor 183
GRPR gastrin-releasing peptide receptor
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
H2BFS H2B histone family, member S (pseudogene)
HDAC9 histone deacetylase 9
HIST1H2BE histone cluster 1, H2be
JMJD4 jumonji domain containing 4
KCTD3 potassium channel tetramerization domain containing 3
KIFAP3 kinesin-associated protein 3
KLHL21 kelch-like family member 21
LAS1L LAS1-like (S. cerevisiae)
LINC00312 long intergenic non-protein coding RNA 312
LMAN1 lectin, mannose-binding, 1
MAGT1 magnesium transporter 1
MBTD1 mbt domain containing 1
METTL18 methyltransferase like 18
MEX3C mex-3 RNA binding family member C
MPC1 mitochondrial pyruvate carrier 1
MRPL33 mitochondrial ribosomal protein L33
MYL12B myosin, light chain 12B, regulatory
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
NFE2L2 nuclear factor, erythroid 2-like 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
PAK1IP1 PAK1 interacting protein 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIBF1 progesterone immunomodulatory binding factor 1
PID1 phosphotyrosine interaction domain containing 1
POMT1 protein-O-mannosyltransferase 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PRKX protein kinase, X-linked
PRRC1 proline-rich coiled-coil 1
PSG4 pregnancy specific beta-1-glycoprotein 4
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RIOK2 RIO kinase 2
RSL24D1 ribosomal L24 domain containing 1
SAMHD1 SAM domain and HD domain 1
SDCCAG3 serologically defined colon cancer antigen 3
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEH1L SEH1-like (S. cerevisiae)
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SLC35A5 solute carrier family 35, member A5
SLPI secretory leukocyte peptidase inhibitor
SNX6 sorting nexin 6
STK39 serine threonine kinase 39
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM14A transmembrane protein 14A
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSLIG2 tRNA splicing ligase complex subunit 2
TTF2 transcription termination factor, RNA polymerase II
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2O ubiquitin-conjugating enzyme E2O
UBXN6 UBX domain protein 6
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
ZEB2 zinc finger E-box binding homeobox 2
ZNF175 zinc finger protein 175
ZNF189 zinc finger protein 189
ZNF217 zinc finger protein 217
ZNF250 zinc finger protein 250
ZNF408 zinc finger protein 408