xylometazoline-2107 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the xylometazoline-2107 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACE angiotensin I converting enzyme
AIRE autoimmune regulator
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARL3 ADP-ribosylation factor-like 3
ARSB arylsulfatase B
AVL9 AVL9 homolog (S. cerevisiase)
BAIAP3 BAI1-associated protein 3
BLZF1 basic leucine zipper nuclear factor 1
CACFD1 calcium channel flower domain containing 1
CACYBP calcyclin binding protein
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CEP135 centrosomal protein 135kDa
CFAP45 cilia and flagella associated protein 45
CPNE7 copine VII
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DLL3 delta-like 3 (Drosophila)
DLX4 distal-less homeobox 4
DUSP21 dual specificity phosphatase 21
EGR1 early growth response 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ELOVL5 ELOVL fatty acid elongase 5
EMP1 epithelial membrane protein 1
ENG endoglin
FAM174B family with sequence similarity 174, member B
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAL3ST4 galactose-3-O-sulfotransferase 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPX2 glutathione peroxidase 2
GRIK5 glutamate receptor, ionotropic, kainate 5
HIST1H2AJ histone cluster 1, H2aj
HNF4A hepatocyte nuclear factor 4, alpha
HOXB5 homeobox B5
IL11RA interleukin 11 receptor, alpha
IL15 interleukin 15
KLHL25 kelch-like family member 25
LRP1 low density lipoprotein receptor-related protein 1
LRP3 low density lipoprotein receptor-related protein 3
LRP4 low density lipoprotein receptor-related protein 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MUC3B mucin 3B, cell surface associated
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOP14-AS1 NOP14 antisense RNA 1
NPR1 natriuretic peptide receptor 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NTF3 neurotrophin 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDH12 protocadherin 12
PCDHB13 protocadherin beta 13
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDAP1 PDGFA associated protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PMEL premelanosome protein
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP5C protein phosphatase 5, catalytic subunit
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRR14L proline rich 14-like
RGS10 regulator of G-protein signaling 10
RHOBTB2 Rho-related BTB domain containing 2
RIMS3 regulating synaptic membrane exocytosis 3
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX3 runt-related transcription factor 3
RWDD2A RWD domain containing 2A
S100A11 S100 calcium binding protein A11
SCARB2 scavenger receptor class B, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC3 syndecan 3
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SETD1A SET domain containing 1A
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNPH syntaphilin
STMN4 stathmin-like 4
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYN2 synapsin II
TBX19 T-box 19
TLE4 transducin-like enhancer of split 4
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TOM1 target of myb1 (chicken)
TRIM14 tripartite motif containing 14
TRIM23 tripartite motif containing 23
TRIM9 tripartite motif containing 9
TSKU tsukushi, small leucine rich proteoglycan
TSSK2 testis-specific serine kinase 2
TTC12 tetratricopeptide repeat domain 12
UNC119 unc-119 homolog (C. elegans)
USF2 upstream transcription factor 2, c-fos interacting
WAS Wiskott-Aldrich syndrome
WDR62 WD repeat domain 62
ZBTB43 zinc finger and BTB domain containing 43
ZMYM2 zinc finger, MYM-type 2
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AEN apoptosis enhancing nuclease
ANXA2P3 annexin A2 pseudogene 3
APH1B APH1B gamma secretase subunit
ARHGAP11A Rho GTPase activating protein 11A
ARID4A AT rich interactive domain 4A (RBP1-like)
ATG2B autophagy related 2B
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF56 chromosome 1 open reading frame 56
C5ORF28 chromosome 5 open reading frame 28
CAMTA2 calmodulin binding transcription activator 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CHPF chondroitin polymerizing factor
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
COA7 cytochrome c oxidase assembly factor 7 (putative)
CORO1A coronin, actin binding protein, 1A
CTSO cathepsin O
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DENND5B DENN/MADD domain containing 5B
ECM1 extracellular matrix protein 1
EFNA3 ephrin-A3
ERF Ets2 repressor factor
EXOC5 exocyst complex component 5
FANCC Fanconi anemia, complementation group C
FCHO1 FCH domain only 1
FKBP10 FK506 binding protein 10, 65 kDa
FLRT3 fibronectin leucine rich transmembrane protein 3
FZD8 frizzled class receptor 8
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALK1 galactokinase 1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GJC1 gap junction protein, gamma 1, 45kDa
GLT8D2 glycosyltransferase 8 domain containing 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPHN gephyrin
GPKOW G patch domain and KOW motifs
HIRA histone cell cycle regulator
HIST1H3H histone cluster 1, H3h
HYAL3 hyaluronoglucosaminidase 3
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
KDM4D lysine (K)-specific demethylase 4D
LYPD1 LY6/PLAUR domain containing 1
LYRM2 LYR motif containing 2
MAGEH1 melanoma antigen family H1
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MICALL2 MICAL-like 2
NCS1 neuronal calcium sensor 1
NHLRC2 NHL repeat containing 2
NMD3 NMD3 ribosome export adaptor
NPM3 nucleophosmin/nucleoplasmin 3
NUPL2 nucleoporin like 2
OCLN occludin
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OSMR oncostatin M receptor
OSR2 odd-skipped related transciption factor 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POTEKP POTE ankyrin domain family, member K, pseudogene
PPT2 palmitoyl-protein thioesterase 2
PRAME preferentially expressed antigen in melanoma
PRKX protein kinase, X-linked
PROCR protein C receptor, endothelial
PSKH1 protein serine kinase H1
RAB25 RAB25, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RANBP17 RAN binding protein 17
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN1 Ras and Rab interactor 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TAGLN transgelin
TMEM242 transmembrane protein 242
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
TWISTNB TWIST neighbor
TXLNG taxilin gamma
UBQLN4 ubiquilin 4
USP32 ubiquitin specific peptidase 32
ZNF124 zinc finger protein 124
ZNF14 zinc finger protein 14
ZNF280D zinc finger protein 280D
ZNF34 zinc finger protein 34
ZNF586 zinc finger protein 586
ZNF665 zinc finger protein 665
ZNF8 zinc finger protein 8
ZNF839 zinc finger protein 839