| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the xylometazoline-2270 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACACB | acetyl-CoA carboxylase beta |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ATP12A | ATPase, H+/K+ transporting, nongastric, alpha polypeptide |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| C2ORF72 | chromosome 2 open reading frame 72 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CARD9 | caspase recruitment domain family, member 9 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD96 | CD96 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHL1 | cell adhesion molecule L1-like |
| COL1A1 | collagen, type I, alpha 1 |
| CRYGD | crystallin, gamma D |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DRD1 | dopamine receptor D1 |
| DSG3 | desmoglein 3 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESM1 | endothelial cell-specific molecule 1 |
| FBLN1 | fibulin 1 |
| FGF6 | fibroblast growth factor 6 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GLS | glutaminase |
| GPR137 | G protein-coupled receptor 137 |
| GYPB | glycophorin B (MNS blood group) |
| HDLBP | high density lipoprotein binding protein |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXB5 | homeobox B5 |
| HP | haptoglobin |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IFNA8 | interferon, alpha 8 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KLF12 | Kruppel-like factor 12 |
| LIMK1 | LIM domain kinase 1 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRRC6 | leucine rich repeat containing 6 |
| LYZ | lysozyme |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MED25 | mediator complex subunit 25 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MID1 | midline 1 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MINK1 | misshapen-like kinase 1 |
| MORC1 | MORC family CW-type zinc finger 1 |
| MOS | v-mos Moloney murine sarcoma viral oncogene homolog |
| MUC3B | mucin 3B, cell surface associated |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUDC | nudC nuclear distribution protein |
| PAX8 | paired box 8 |
| PCDH12 | protocadherin 12 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDGFD | platelet derived growth factor D |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLCE1 | phospholipase C, epsilon 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKCQ | protein kinase C, theta |
| PSCA | prostate stem cell antigen |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RGS12 | regulator of G-protein signaling 12 |
| RGS14 | regulator of G-protein signaling 14 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX1 | runt-related transcription factor 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SDC3 | syndecan 3 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPAG8 | sperm associated antigen 8 |
| SRGN | serglycin |
| STEAP4 | STEAP family member 4 |
| TAOK2 | TAO kinase 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOX | thymocyte selection-associated high mobility group box |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM3 | tripartite motif containing 3 |
| TSSK2 | testis-specific serine kinase 2 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| ZNF286A | zinc finger protein 286A |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABHD17B | abhydrolase domain containing 17B |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKRD36 | ankyrin repeat domain 36 |
| AR | androgen receptor |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC121 | coiled-coil domain containing 121 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CENPJ | centromere protein J |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN1 | claudin 1 |
| CLSPN | claspin |
| CNTN1 | contactin 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DSCAM | Down syndrome cell adhesion molecule |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERCC4 | excision repair cross-complementation group 4 |
| ETNK2 | ethanolamine kinase 2 |
| FAM131A | family with sequence similarity 131, member A |
| FAM53B | family with sequence similarity 53, member B |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GPR21 | G protein-coupled receptor 21 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IFT22 | intraflagellar transport 22 |
| INO80D | INO80 complex subunit D |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KLHDC8A | kelch domain containing 8A |
| KLHL12 | kelch-like family member 12 |
| KLHL21 | kelch-like family member 21 |
| KLHL28 | kelch-like family member 28 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCC | mutated in colorectal cancers |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP9 | matrix metallopeptidase 9 |
| MTCP1 | mature T-cell proliferation 1 |
| N4BP3 | NEDD4 binding protein 3 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCD1 | phospholipase C, delta 1 |
| PMCH | pro-melanin-concentrating hormone |
| PODXL2 | podocalyxin-like 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3A | RAB3A, member RAS oncogene family |
| RASL11B | RAS-like, family 11, member B |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF122 | ring finger protein 122 |
| RNF43 | ring finger protein 43 |
| RPAIN | RPA interacting protein |
| RPL10L | ribosomal protein L10-like |
| S100A4 | S100 calcium binding protein A4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SETD1A | SET domain containing 1A |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SPRYD7 | SPRY domain containing 7 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TDRD1 | tudor domain containing 1 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM242 | transmembrane protein 242 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| UBQLN4 | ubiquilin 4 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF280D | zinc finger protein 280D |
| ZNF76 | zinc finger protein 76 |
