yap1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Yes-associated protein 1|This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] (NCBI Entrez Gene Database, 10413)
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Genes

24 genes co-occuring with the biological term yap1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AGR2 anterior gradient 2
ANKHD1 ankyrin repeat and KH domain containing 1
AREG amphiregulin
AXL AXL receptor tyrosine kinase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
ITCH itchy E3 ubiquitin protein ligase
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS2 large tumor suppressor kinase 2
MEN1 multiple endocrine neoplasia I
MIR141 microRNA 141
MIR200A microRNA 200a
MIR31 microRNA 31
MIR375 microRNA 375
NF2 neurofibromin 2 (merlin)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
SAV1 salvador family WW domain containing protein 1
SHH sonic hedgehog
STK4 serine/threonine kinase 4
TBX5 T-box 5
TP53BP2 tumor protein p53 binding protein 2
TP63 tumor protein p63
TP73 tumor protein p73
VGLL3 vestigial-like family member 3
YAP1 Yes-associated protein 1