yap1_18413746_mcf10a_gof_human_gpl570_gds3220 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS3220
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Genes

587 genes differentially expressed following the yap1_18413746_mcf10a_gof_human_gpl570_gds3220 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.229591
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.229263
VEZT vezatin, adherens junctions transmembrane protein 0.224681
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.221651
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.217573
AFTPH aftiphilin 0.215446
RPS12 ribosomal protein S12 0.214975
WNT1 wingless-type MMTV integration site family, member 1 0.214823
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.214644
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.214547
MIER3 mesoderm induction early response 1, family member 3 0.214298
MMP24 matrix metallopeptidase 24 (membrane-inserted) 0.213184
CAPN7 calpain 7 0.210856
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.209527
ZYX zyxin 0.208518
NAT6 N-acetyltransferase 6 (GCN5-related) 0.206873
KIF13A kinesin family member 13A 0.206284
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.204744
CPEB3 cytoplasmic polyadenylation element binding protein 3 0.204644
SOCS3 suppressor of cytokine signaling 3 0.200793
MAN2A2 mannosidase, alpha, class 2A, member 2 0.199952
KLF2 Kruppel-like factor 2 0.19791
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene 0.194383
HINT1 histidine triad nucleotide binding protein 1 0.193656
PARP10 poly (ADP-ribose) polymerase family, member 10 0.193464
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 0.191797
ACOT1 acyl-CoA thioesterase 1 0.191527
MAPT-AS1 MAPT antisense RNA 1 0.189252
ZNF226 zinc finger protein 226 0.186582
MVB12B multivesicular body subunit 12B 0.185708
YIPF5 Yip1 domain family, member 5 0.185377
GPRIN3 GPRIN family member 3 0.184969
CCDC97 coiled-coil domain containing 97 0.18442
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.183338
PFN1 profilin 1 0.182623
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase 0.182243
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 0.181909
EFCAB6 EF-hand calcium binding domain 6 0.181803
KCTD2 potassium channel tetramerization domain containing 2 0.179644
EZR ezrin 0.177069
CLCF1 cardiotrophin-like cytokine factor 1 0.177007
LOC729083 uncharacterized LOC729083 0.176806
MEGF6 multiple EGF-like-domains 6 0.17197
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14 0.170546
UBA6 ubiquitin-like modifier activating enzyme 6 0.169334
ZDHHC2 zinc finger, DHHC-type containing 2 0.168632
PRR5L proline rich 5 like 0.166998
OPTN optineurin 0.166128
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.163467
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.161826
C4ORF45 chromosome 4 open reading frame 45 0.159613
TFDP1 transcription factor Dp-1 0.159409
HLA-B major histocompatibility complex, class I, B 0.159097
DBR1 debranching RNA lariats 1 0.156204
BIRC2 baculoviral IAP repeat containing 2 0.155576
TMEM194A transmembrane protein 194A 0.155576
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.155513
GK5 glycerol kinase 5 (putative) 0.151452
MYNN myoneurin 0.149245
CCDC65 coiled-coil domain containing 65 0.148283
MYL9 myosin, light chain 9, regulatory 0.147057
HPS5 Hermansky-Pudlak syndrome 5 0.146346
FAM24B family with sequence similarity 24, member B 0.14543
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0.143917
UCMA upper zone of growth plate and cartilage matrix associated 0.140811
FADS3 fatty acid desaturase 3 0.140291
NMT1 N-myristoyltransferase 1 0.139867
AK5 adenylate kinase 5 0.138813
NLN neurolysin (metallopeptidase M3 family) 0.135287
FRMD6 FERM domain containing 6 0.135114
PROSER2 proline and serine rich 2 0.134861
P4HB prolyl 4-hydroxylase, beta polypeptide 0.134089
CEP57 centrosomal protein 57kDa 0.132377
PALM2-AKAP2 PALM2-AKAP2 readthrough 0.132157
OTUD7B OTU deubiquitinase 7B 0.127564
MYEOV2 myeloma overexpressed 2 0.125857
UBASH3B ubiquitin associated and SH3 domain containing B 0.125825
PROS1 protein S (alpha) 0.123063
PQLC3 PQ loop repeat containing 3 0.122392
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.122189
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.12194
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.121457
POLRMTP1 polymerase (RNA) mitochondrial (DNA directed) pseudogene 1 0.120866
ZSCAN2 zinc finger and SCAN domain containing 2 0.119172
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.118364
AGXT alanine-glyoxylate aminotransferase 0.117775
ZDHHC21 zinc finger, DHHC-type containing 21 0.117078
AACSP1 acetoacetyl-CoA synthetase pseudogene 1 0.113014
ZNF674-AS1 ZNF674 antisense RNA 1 (head to head) 0.109816
TJP2 tight junction protein 2 0.107657
CYR61 cysteine-rich, angiogenic inducer, 61 0.104379
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.104014
AMOTL2 angiomotin like 2 0.103877
DPY19L4 dpy-19-like 4 (C. elegans) 0.10286
IGHV3-48 immunoglobulin heavy variable 3-48 0.102102
FNBP1 formin binding protein 1 0.100953
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.100424
RAD51 RAD51 recombinase 0.100212
AGA aspartylglucosaminidase 0.099533
TMOD3 tropomodulin 3 (ubiquitous) 0.098825
FLII flightless I homolog (Drosophila) 0.0986
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 0.098164
PAM peptidylglycine alpha-amidating monooxygenase 0.095404
ZHX2 zinc fingers and homeoboxes 2 0.095106
KLHDC10 kelch domain containing 10 0.094613
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.090747
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 0.08983
NUMB numb homolog (Drosophila) 0.088738
SNAP25 synaptosomal-associated protein, 25kDa 0.088443
COPB1 coatomer protein complex, subunit beta 1 0.087516
CALHM2 calcium homeostasis modulator 2 0.086107
ACKR3 atypical chemokine receptor 3 0.085975
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.084732
RAB4B RAB4B, member RAS oncogene family 0.082751
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.081909
TRIP4 thyroid hormone receptor interactor 4 0.081445
TSEN15 TSEN15 tRNA splicing endonuclease subunit 0.080158
NPAS4 neuronal PAS domain protein 4 0.079739
LOC780529 uncharacterized LOC780529 0.079638
SYTL4 synaptotagmin-like 4 0.07948
GP2 glycoprotein 2 (zymogen granule membrane) 0.077109
NEBL nebulette 0.07605
MARC1 mitochondrial amidoxime reducing component 1 0.073375
PLSCR1 phospholipid scramblase 1 0.072398
ERBB2 erb-b2 receptor tyrosine kinase 2 0.072044
SNX24 sorting nexin 24 0.071508
ZNF638 zinc finger protein 638 0.071255
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 0.07117
CCDC80 coiled-coil domain containing 80 0.069525
TRAF3IP2-AS1 TRAF3IP2 antisense RNA 1 0.068056
ANXA3 annexin A3 0.067777
GPBP1 GC-rich promoter binding protein 1 0.067596
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 0.067596
ZNF385B zinc finger protein 385B 0.067554
CDC16 cell division cycle 16 0.067373
RANBP17 RAN binding protein 17 0.066593
LOC644450 uncharacterized LOC644450 0.065634
NPHP1 nephronophthisis 1 (juvenile) 0.065357
PEG3 paternally expressed 3 0.063562
TLR6 toll-like receptor 6 0.058518
ARRB2 arrestin, beta 2 0.056951
TAZ tafazzin 0.054961
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.053949
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 0.051009
RNASE4 ribonuclease, RNase A family, 4 0.049681
HDLBP high density lipoprotein binding protein 0.047514
MYO5A myosin VA (heavy chain 12, myoxin) 0.046786
SRGN serglycin 0.042253
ILF3 interleukin enhancer binding factor 3, 90kDa 0.041539
ADPGK ADP-dependent glucokinase 0.040031
CCDC180 coiled-coil domain containing 180 0.038474
SYNPO2L synaptopodin 2-like 0.037545
IDS iduronate 2-sulfatase 0.037349
TUBB2A tubulin, beta 2A class IIa 0.036143
RASA2 RAS p21 protein activator 2 0.03553
MCFD2 multiple coagulation factor deficiency 2 0.035001
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.034862
DPP9 dipeptidyl-peptidase 9 0.034779
TRIO trio Rho guanine nucleotide exchange factor 0.034751
CDC14B cell division cycle 14B 0.03342
TXNDC15 thioredoxin domain containing 15 0.032784
PODXL podocalyxin-like 0.032125
GUK1 guanylate kinase 1 0.027955
SORBS2 sorbin and SH3 domain containing 2 0.027198
TPK1 thiamin pyrophosphokinase 1 0.026286
AIDA axin interactor, dorsalization associated 0.022721
FBLN1 fibulin 1 0.021428
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.020357
OPN3 opsin 3 0.019731
LOX lysyl oxidase 0.01955
SCARB2 scavenger receptor class B, member 2 0.017195
IPO5 importin 5 0.017092
USP48 ubiquitin specific peptidase 48 0.014815
SH3BGRL SH3 domain binding glutamate-rich protein like 0.014104
MAPK14 mitogen-activated protein kinase 14 0.013268
GLTPD2 glycolipid transfer protein domain containing 2 0.012889
LOC285074 anaphase promoting complex subunit 1 pseudogene 0.012713
KCTD21 potassium channel tetramerization domain containing 21 0.012662
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.011285
EXT1 exostosin glycosyltransferase 1 0.009839
PLIN5 perilipin 5 0.009542
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.009023
PDZD11 PDZ domain containing 11 0.007348
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.005206
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00472
SLC35E1 solute carrier family 35, member E1 0.003855
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.003808
NRD1 nardilysin (N-arginine dibasic convertase) 0.003376
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.003112
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.002945
SLC37A3 solute carrier family 37, member 3 0.001231
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.001066
STX7 syntaxin 7 3.09E-4

decreased expression

Symbol Name Standardized Value
PTGIS prostaglandin I2 (prostacyclin) synthase -1.3412
MXD4 MAX dimerization protein 4 -1.3345
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -1.33313
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -1.29896
GSTM3 glutathione S-transferase mu 3 (brain) -1.29364
LINC00588 long intergenic non-protein coding RNA 588 -1.29088
EML3 echinoderm microtubule associated protein like 3 -1.2883
PDCL phosducin-like -1.28739
RFESD Rieske (Fe-S) domain containing -1.2813
ARHGAP24 Rho GTPase activating protein 24 -1.27885
CLINT1 clathrin interactor 1 -1.27591
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -1.27216
MRPL35 mitochondrial ribosomal protein L35 -1.26754
ZFAND6 zinc finger, AN1-type domain 6 -1.25035
ING5 inhibitor of growth family, member 5 -1.24978
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -1.24113
SOAT2 sterol O-acyltransferase 2 -1.22624
WASF3 WAS protein family, member 3 -1.22504
TRPT1 tRNA phosphotransferase 1 -1.21936
PDE4DIP phosphodiesterase 4D interacting protein -1.21499
ETV6 ets variant 6 -1.2137
MRPS25 mitochondrial ribosomal protein S25 -1.20891
LOC375196 uncharacterized LOC375196 -1.20488
ESRP1 epithelial splicing regulatory protein 1 -1.19178
GPR88 G protein-coupled receptor 88 -1.17277
BEST3 bestrophin 3 -1.1558
PEX5L peroxisomal biogenesis factor 5-like -1.15288
MCTP1 multiple C2 domains, transmembrane 1 -1.1481
KPNA6 karyopherin alpha 6 (importin alpha 7) -1.1438
IL1RL2 interleukin 1 receptor-like 2 -1.13883
TPI1 triosephosphate isomerase 1 -1.13324
SLAIN2 SLAIN motif family, member 2 -1.13077
CD84 CD84 molecule -1.13077
FMNL3 formin-like 3 -1.12861
ALOX15B arachidonate 15-lipoxygenase, type B -1.12376
LINC00847 long intergenic non-protein coding RNA 847 -1.11911
CLCN4 chloride channel, voltage-sensitive 4 -1.11844
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -1.11091
ADAM20 ADAM metallopeptidase domain 20 -1.10814
PCSK7 proprotein convertase subtilisin/kexin type 7 -1.10666
FAM49A family with sequence similarity 49, member A -1.10135
ADAT1 adenosine deaminase, tRNA-specific 1 -1.0846
LOC283693 -1.07411
NABP2 nucleic acid binding protein 2 -1.05988
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -1.0596
XYLB xylulokinase homolog (H. influenzae) -1.05925
GAS2L2 growth arrest-specific 2 like 2 -1.05758
PXK PX domain containing serine/threonine kinase -1.04547
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 -1.04423
LOC283070 -1.0334
ITGB6 integrin, beta 6 -1.02119
SLC25A38 solute carrier family 25, member 38 -1.02105
FAM83F family with sequence similarity 83, member F -1.017
DFNA5 deafness, autosomal dominant 5 -1.01034
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -1.00428
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.996065
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 -0.992174
FAM212B family with sequence similarity 212, member B -0.991916
SHISA3 shisa family member 3 -0.991464
NSFL1C NSFL1 (p97) cofactor (p47) -0.983971
NFX1 nuclear transcription factor, X-box binding 1 -0.983585
BTBD11 BTB (POZ) domain containing 11 -0.977007
MAGEB18 melanoma antigen family B18 -0.972202
NSUN4 NOP2/Sun domain family, member 4 -0.966321
LIMK2 LIM domain kinase 2 -0.958973
MGC15885 uncharacterized protein MGC15885 -0.952586
TTTY13 testis-specific transcript, Y-linked 13 (non-protein coding) -0.946335
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -0.945241
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) -0.94512
HSPB8 heat shock 22kDa protein 8 -0.944271
MEF2A myocyte enhancer factor 2A -0.9416
FANCD2 Fanconi anemia, complementation group D2 -0.940869
WWC2 WW and C2 domain containing 2 -0.940747
LOC729291 uncharacterized LOC729291 -0.93844
PI4K2B phosphatidylinositol 4-kinase type 2 beta -0.937231
PHC2 polyhomeotic homolog 2 (Drosophila) -0.922383
CLCN3 chloride channel, voltage-sensitive 3 -0.917683
CD5L CD5 molecule-like -0.915062
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 -0.914307
RPP14 ribonuclease P/MRP 14kDa subunit -0.910115
UHMK1 U2AF homology motif (UHM) kinase 1 -0.90936
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -0.905378
DCHS1 dachsous cadherin-related 1 -0.900295
LMNTD1 lamin tail domain containing 1 -0.893927
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -0.888422
C5ORF24 chromosome 5 open reading frame 24 -0.887084
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -0.883574
DNASE1 deoxyribonuclease I -0.878754
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.878148
OXR1 oxidation resistance 1 -0.876062
UBE3D ubiquitin protein ligase E3D -0.876062
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -0.874859
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.871974
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.86074
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -0.859941
GTDC1 glycosyltransferase-like domain containing 1 -0.85909
LONRF3 LON peptidase N-terminal domain and ring finger 3 -0.858505
LINC00851 long intergenic non-protein coding RNA 851 -0.855522
KIAA1468 KIAA1468 -0.851401
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.849303
ZNF583 zinc finger protein 583 -0.849199
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.848519
MRI1 methylthioribose-1-phosphate isomerase 1 -0.846747
SQLE squalene epoxidase -0.842014
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.836404
THBD thrombomodulin -0.832174
KRTAP1-5 keratin associated protein 1-5 -0.830497
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) -0.830243
TINAG tubulointerstitial nephritis antigen -0.82923
MUC13 mucin 13, cell surface associated -0.815459
C1ORF100 chromosome 1 open reading frame 100 -0.812709
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -0.81217
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.809684
TRDV3 T cell receptor delta variable 3 -0.807205
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -0.806671
FASTKD1 FAST kinase domains 1 -0.798411
SPHK2 sphingosine kinase 2 -0.794282
CHAT choline O-acetyltransferase -0.793007
SRSF8 serine/arginine-rich splicing factor 8 -0.792065
ISCA1 iron-sulfur cluster assembly 1 -0.784924
RAB3A RAB3A, member RAS oncogene family -0.783765
RITA1 RBPJ interacting and tubulin associated 1 -0.783441
CMIP c-Maf inducing protein -0.770762
INO80D INO80 complex subunit D -0.76557
FAM83A family with sequence similarity 83, member A -0.765259
LOC100130700 uncharacterized LOC100130700 -0.754012
ITGA7 integrin, alpha 7 -0.753145
AJAP1 adherens junctions associated protein 1 -0.749951
PHF20L1 PHD finger protein 20-like 1 -0.748234
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 -0.745884
NPSR1-AS1 NPSR1 antisense RNA 1 -0.744735
SH3PXD2A-AS1 SH3PXD2A antisense RNA 1 -0.740589
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit -0.738782
MYL10 myosin, light chain 10, regulatory -0.731753
PCBP2 poly(rC) binding protein 2 -0.731671
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.730929
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.727362
CT83 cancer/testis antigen 83 -0.721845
TLE6 transducin-like enhancer of split 6 -0.719715
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) -0.718355
GPATCH1 G patch domain containing 1 -0.715369
ARHGAP22 Rho GTPase activating protein 22 -0.713508
HBA2 hemoglobin, alpha 2 -0.711812
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.709305
ZNF821 zinc finger protein 821 -0.708602
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) -0.708524
TBX1 T-box 1 -0.705493
PITPNB phosphatidylinositol transfer protein, beta -0.702405
GFER growth factor, augmenter of liver regeneration -0.699994
IFNA14 interferon, alpha 14 -0.6968
SCARB1 scavenger receptor class B, member 1 -0.696611
NKD1 naked cuticle homolog 1 (Drosophila) -0.696535
LOC100129603 uncharacterized LOC100129603 -0.695363
LMO2 LIM domain only 2 (rhombotin-like 1) -0.692653
SLC25A39 solute carrier family 25, member 39 -0.691569
KIAA1919 KIAA1919 -0.691495
IFI16 interferon, gamma-inducible protein 16 -0.69101
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -0.689261
M1AP meiosis 1 associated protein -0.686853
SNAI3 snail family zinc finger 3 -0.682047
NPAS3 neuronal PAS domain protein 3 -0.67889
FAM134B family with sequence similarity 134, member B -0.67687
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 -0.675039
METTL6 methyltransferase like 6 -0.670456
ERAP1 endoplasmic reticulum aminopeptidase 1 -0.66894
FHL5 four and a half LIM domains 5 -0.664046
GJB3 gap junction protein, beta 3, 31kDa -0.661505
ZDHHC22 zinc finger, DHHC-type containing 22 -0.658443
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.655868
BRDT bromodomain, testis-specific -0.655414
TPPP2 tubulin polymerization-promoting protein family member 2 -0.652556
CHPF chondroitin polymerizing factor -0.649198
ERICH3 glutamate-rich 3 -0.64868
MED6 mediator complex subunit 6 -0.6431
INVS inversin -0.639911
RNF14 ring finger protein 14 -0.63675
TGS1 trimethylguanosine synthase 1 -0.636249
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a -0.636249
MCTS1 malignant T cell amplified sequence 1 -0.634681
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -0.627443
ERVMER34-1 endogenous retrovirus group MER34, member 1 -0.627374
MYLK3 myosin light chain kinase 3 -0.614767
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 -0.611905
DHODH dihydroorotate dehydrogenase (quinone) -0.60829
SLC25A34 solute carrier family 25, member 34 -0.607833
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 -0.60718
MEIS1 Meis homeobox 1 -0.606268
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor -0.605812
PAX5 paired box 5 -0.601751
BCL2L10 BCL2-like 10 (apoptosis facilitator) -0.601174
ALKBH5 AlkB family member 5, RNA demethylase -0.599011
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -0.597678
AGR3 anterior gradient 3 -0.594728
MMRN1 multimerin 1 -0.592113
LINC00486 long intergenic non-protein coding RNA 486 -0.589822
DMRT2 doublesex and mab-3 related transcription factor 2 -0.589456
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.588965
TSNAX translin-associated factor X -0.586162
SCAMP1 secretory carrier membrane protein 1 -0.585313
SPEG SPEG complex locus -0.583922
ADAMTSL1 ADAMTS-like 1 -0.582659
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.580394
EIF1B-AS1 EIF1B antisense RNA 1 -0.577374
ASH1L-AS1 ASH1L antisense RNA 1 -0.575557
PPIF peptidylprolyl isomerase F -0.575034
ACSS1 acyl-CoA synthetase short-chain family member 1 -0.568351
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -0.562554
LOC399491 -0.562054
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 -0.558189
BEND5 BEN domain containing 5 -0.554933
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -0.554286
TESC tescalcin -0.554071
CCDC106 coiled-coil domain containing 106 -0.552455
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.551549
PODNL1 podocan-like 1 -0.550012
GTF2H5 general transcription factor IIH, polypeptide 5 -0.548534
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -0.545393
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 -0.54498
FAN1 FANCD2/FANCI-associated nuclease 1 -0.536678
KDM4B lysine (K)-specific demethylase 4B -0.532465
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -0.531435
ULBP2 UL16 binding protein 2 -0.5308
HEPACAM2 HEPACAM family member 2 -0.528808
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -0.527943
LRRC52 leucine rich repeat containing 52 -0.52455
CDC27 cell division cycle 27 -0.523185
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 -0.520242
COL1A2 collagen, type I, alpha 2 -0.519682
BHMT2 betaine--homocysteine S-methyltransferase 2 -0.519636
ARID4B AT rich interactive domain 4B (RBP1-like) -0.514748
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.513756
TMC7 transmembrane channel-like 7 -0.50892
CBX4 chromobox homolog 4 -0.507487
SGSM1 small G protein signaling modulator 1 -0.505669
DPYD dihydropyrimidine dehydrogenase -0.504633
NR2C1 nuclear receptor subfamily 2, group C, member 1 -0.503739
LOC283454 uncharacterized LOC283454 -0.501457
ITGA9 integrin, alpha 9 -0.501204
LHX3 LIM homeobox 3 -0.501162
TPTE2P2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 2 -0.500026
POU5F1P4 POU class 5 homeobox 1 pseudogene 4 -0.499526
UBXN10 UBX domain protein 10 -0.498247
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.497507
CCNF cyclin F -0.497342
CBX5 chromobox homolog 5 -0.496891
PPP6R1 protein phosphatase 6, regulatory subunit 1 -0.49517
ZNF79 zinc finger protein 79 -0.492841
COL9A1 collagen, type IX, alpha 1 -0.490687
AKR1C1 aldo-keto reductase family 1, member C1 -0.49057
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) -0.487994
NOP16 NOP16 nucleolar protein -0.487254
NUMA1 nuclear mitotic apparatus protein 1 -0.486672
CDK17 cyclin-dependent kinase 17 -0.484236
ZCCHC6 zinc finger, CCHC domain containing 6 -0.482307
RFC3 replication factor C (activator 1) 3, 38kDa -0.482121
NFS1 NFS1 cysteine desulfurase -0.481937
GJC1 gap junction protein, gamma 1, 45kDa -0.481307
TOX4 TOX high mobility group box family member 4 -0.481121
TRIM14 tripartite motif containing 14 -0.479646
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -0.477169
MGAM maltase-glucoamylase -0.476487
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -0.475484
CACUL1 CDK2-associated, cullin domain 1 -0.474517
KLHL41 kelch-like family member 41 -0.473639
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.473289
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -0.473255
PRF1 perforin 1 (pore forming protein) -0.471756
ZDHHC13 zinc finger, DHHC-type containing 13 -0.471581
WDR77 WD repeat domain 77 -0.469723
LUZP1 leucine zipper protein 1 -0.469519
LINC00564 long intergenic non-protein coding RNA 564 -0.469519
LPAR3 lysophosphatidic acid receptor 3 -0.469044
LRG1 leucine-rich alpha-2-glycoprotein 1 -0.463394
METTL21EP methyltransferase like 21E, pseudogene -0.463231
AUP1 ancient ubiquitous protein 1 -0.462781
KMT2A lysine (K)-specific methyltransferase 2A -0.462461
EDA ectodysplasin A -0.46243
NEK1 NIMA-related kinase 1 -0.462206
TIGD7 tigger transposable element derived 7 -0.461217
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.459723
HIST1H4PS1 histone cluster 1, H4, pseudogene 1 -0.45941
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.458296
SAMD14 sterile alpha motif domain containing 14 -0.455748
DGCR12 DiGeorge syndrome critical region gene 12 (non-protein coding) -0.455178
TMEM33 transmembrane protein 33 -0.453683
ZNF76 zinc finger protein 76 -0.453355
STK33 serine/threonine kinase 33 -0.453205
SPRY4-IT1 SPRY4 intronic transcript 1 -0.451716
DPYSL3 dihydropyrimidinase-like 3 -0.451426
USP42 ubiquitin specific peptidase 42 -0.45079
ZDHHC18 zinc finger, DHHC-type containing 18 -0.450587
SNX21 sorting nexin family member 21 -0.449524
ZNF800 zinc finger protein 800 -0.449298
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 -0.448624
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.444874
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 -0.443953
ZFP28 ZFP28 zinc finger protein -0.443604
CLEC4A C-type lectin domain family 4, member A -0.442791
AKT1S1 AKT1 substrate 1 (proline-rich) -0.442241
NME9 NME/NM23 family member 9 -0.440523
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -0.43979
SLC10A7 solute carrier family 10, member 7 -0.439588
LOC100505622 uncharacterized LOC100505622 -0.438755
HCP5 HLA complex P5 (non-protein coding) -0.438679
KIAA1654 KIAA1654 protein -0.438351
KAZN kazrin, periplakin interacting protein -0.437437
BSDC1 BSD domain containing 1 -0.436729
POLR1E polymerase (RNA) I polypeptide E, 53kDa -0.436364
EPS8L1 EPS8-like 1 -0.434565
IRX4 iroquois homeobox 4 -0.434448
SDCCAG3 serologically defined colon cancer antigen 3 -0.433884
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.057447
NAV1 neuron navigator 1 -0.056717
MGLL monoglyceride lipase -0.055174
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -0.055135
BCL2L1 BCL2-like 1 -0.053597
ST7L suppression of tumorigenicity 7 like -0.05324
GORASP2 golgi reassembly stacking protein 2, 55kDa -0.052884
CCND1 cyclin D1 -0.052884
OGFRL1 opioid growth factor receptor-like 1 -0.051817
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) -0.050099
SNX8 sorting nexin 8 -0.049678
ANXA5 annexin A5 -0.049298
NEK11 NIMA-related kinase 11 -0.048506
KCTD9 potassium channel tetramerization domain containing 9 -0.048303
EP400NL EP400 N-terminal like -0.047978
SEC24D SEC24 family member D -0.046758
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.046696
PARP16 poly (ADP-ribose) polymerase family, member 16 -0.045955
NCOR2 nuclear receptor corepressor 2 -0.045153
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.044804
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.044804
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.044638
CNN1 calponin 1, basic, smooth muscle -0.044117
TRIM8 tripartite motif containing 8 -0.043721
SSR1 signal sequence receptor, alpha -0.04318
EXOG endo/exonuclease (5'-3'), endonuclease G-like -0.043118
RPL7L1 ribosomal protein L7-like 1 -0.042599
GLIS2 GLIS family zinc finger 2 -0.042263
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.041968
MED8 mediator complex subunit 8 -0.041504
CCNY cyclin Y -0.041441
MARCKS myristoylated alanine-rich protein kinase C substrate -0.040537
RNF170 ring finger protein 170 -0.04001
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.04001
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.039029
ZCCHC17 zinc finger, CCHC domain containing 17 -0.037496
NECAP2 NECAP endocytosis associated 2 -0.037388
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -0.03685
PTRF polymerase I and transcript release factor -0.036097
TBX5-AS1 TBX5 antisense RNA 1 -0.035301
RPN2 ribophorin II -0.032935
LOC100288911 uncharacterized LOC100288911 -0.032518
DPY30 dpy-30 homolog (C. elegans) -0.032079
PDIA2 protein disulfide isomerase family A, member 2 -0.030569
MCM4 minichromosome maintenance complex component 4 -0.030392
PGAM2 phosphoglycerate mutase 2 (muscle) -0.02669
SQSTM1 sequestosome 1 -0.026534
SETD1B SET domain containing 1B -0.026379
AGO4 argonaute RISC catalytic component 4 -0.025824
MORF4 mortality factor 4 (pseudogene) -0.024118
MCMDC2 minichromosome maintenance domain containing 2 -0.022475
KIAA1107 KIAA1107 -0.022136
NTAN1 N-terminal asparagine amidase -0.021639
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.021301
MORF4L2 mortality factor 4 like 2 -0.02085
RFTN1 raftlin, lipid raft linker 1 -0.020008
LY86-AS1 LY86 antisense RNA 1 -0.019576
TRAM1 translocation associated membrane protein 1 -0.019304
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -0.018213
CAPS2 calcyphosine 2 -0.018099
ST20-AS1 ST20 antisense RNA 1 -0.017389
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.016771
NDNF neuron-derived neurotrophic factor -0.016657
ERCC6L2 excision repair cross-complementation group 6-like 2 -0.016657
RBPMS RNA binding protein with multiple splicing -0.014386
MALT1 MALT1 paracaspase -0.013743
TMEM258 transmembrane protein 258 -0.013674
SRP54 signal recognition particle 54kDa -0.013238
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.012127
DUSP3 dual specificity phosphatase 3 -0.010927
FGF2 fibroblast growth factor 2 (basic) -0.01051
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) -0.010207
TPD52 tumor protein D52 -0.00951
DEFB124 defensin, beta 124 -0.009441
TMEM230 transmembrane protein 230 -0.009394
C1ORF86 chromosome 1 open reading frame 86 -0.009024
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -0.008954
NAV3 neuron navigator 3 -0.006928
SBDSP1 Shwachman-Bodian-Diamond syndrome pseudogene 1 -0.003589
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.002675
TMEM98 transmembrane protein 98 -0.002534
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -0.001994
PGRMC2 progesterone receptor membrane component 2 -1.63E-4
Funding