| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the yohimbic acid-2147 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ATN1 | atrophin 1 |
| B9D2 | B9 protein domain 2 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CD6 | CD6 molecule |
| CDK16 | cyclin-dependent kinase 16 |
| CELP | carboxyl ester lipase pseudogene |
| CFAP45 | cilia and flagella associated protein 45 |
| CHN2 | chimerin 2 |
| CLEC4A | C-type lectin domain family 4, member A |
| CPNE7 | copine VII |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| E2F5 | E2F transcription factor 5, p130-binding |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLJ11292 | |
| GALC | galactosylceramidase |
| GFER | growth factor, augmenter of liver regeneration |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GK3P | glycerol kinase 3 pseudogene |
| GOSR2 | golgi SNAP receptor complex member 2 |
| H2AFX | H2A histone family, member X |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| ITCH | itchy E3 ubiquitin protein ligase |
| KIAA0485 | uncharacterized LOC57235 |
| KIAA1456 | KIAA1456 |
| KRT81 | keratin 81, type II |
| LAMA4 | laminin, alpha 4 |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAP7 | microtubule-associated protein 7 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MCAM | melanoma cell adhesion molecule |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MFAP3 | microfibrillar-associated protein 3 |
| MTA1 | metastasis associated 1 |
| MXD3 | MAX dimerization protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NF2 | neurofibromin 2 (merlin) |
| NIPAL2 | NIPA-like domain containing 2 |
| NNAT | neuronatin |
| NRG2 | neuregulin 2 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP50 | nucleoporin 50kDa |
| OPTN | optineurin |
| PADI4 | peptidyl arginine deiminase, type IV |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PEAK1 | pseudopodium-enriched atypical kinase 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PICK1 | protein interacting with PRKCA 1 |
| PLSCR1 | phospholipid scramblase 1 |
| PTCH2 | patched 2 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB3A | RAB3A, member RAS oncogene family |
| RECQL5 | RecQ protein-like 5 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RGS19 | regulator of G-protein signaling 19 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| RRBP1 | ribosome binding protein 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SLIT2 | slit homolog 2 (Drosophila) |
| SPTB | spectrin, beta, erythrocytic |
| SV2B | synaptic vesicle glycoprotein 2B |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TMEM63A | transmembrane protein 63A |
| TRA | T cell receptor alpha locus |
| TRAF1 | TNF receptor-associated factor 1 |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRIM58 | tripartite motif containing 58 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN2 | tetraspanin 2 |
| TSPYL2 | TSPY-like 2 |
| TULP2 | tubby like protein 2 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| ZNF276 | zinc finger protein 276 |
| ZNF552 | zinc finger protein 552 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| APH1B | APH1B gamma secretase subunit |
| BBC3 | BCL2 binding component 3 |
| BCL2L2 | BCL2-like 2 |
| BNC2 | basonuclin 2 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD69 | CD69 molecule |
| CD82 | CD82 molecule |
| CEP295 | centrosomal protein 295kDa |
| CFP | complement factor properdin |
| CLEC4E | C-type lectin domain family 4, member E |
| COL15A1 | collagen, type XV, alpha 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEFB1 | defensin, beta 1 |
| DFNA5 | deafness, autosomal dominant 5 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOC2A | double C2-like domains, alpha |
| DOK5 | docking protein 5 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EDAR | ectodysplasin A receptor |
| ELMO3 | engulfment and cell motility 3 |
| FAM63A | family with sequence similarity 63, member A |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FUZ | fuzzy planar cell polarity protein |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H4C | histone cluster 1, H4c |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KLHL21 | kelch-like family member 21 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MLPH | melanophilin |
| MMP9 | matrix metallopeptidase 9 |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1E | myosin IE |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OXTR | oxytocin receptor |
| PADI1 | peptidyl arginine deiminase, type I |
| PER3 | period circadian clock 3 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PMCH | pro-melanin-concentrating hormone |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAMEF11 | PRAME family member 11 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRR4 | proline rich 4 (lacrimal) |
| RAB17 | RAB17, member RAS oncogene family |
| RETN | resistin |
| RNF122 | ring finger protein 122 |
| RNF31 | ring finger protein 31 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAI1 | snail family zinc finger 1 |
| TAGLN | transgelin |
| TAOK1 | TAO kinase 1 |
| TMEM246 | transmembrane protein 246 |
| TMEM53 | transmembrane protein 53 |
| TRAC | T cell receptor alpha constant |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM45 | tripartite motif containing 45 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN32 | tetraspanin 32 |
| TUBA4B | tubulin, alpha 4b |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UPB1 | ureidopropionase, beta |
| UPK3A | uroplakin 3A |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF32 | zinc finger protein 32 |
| ZNF749 | zinc finger protein 749 |
| ZNF8 | zinc finger protein 8 |
