| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the yohimbine-1119 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| AHR | aryl hydrocarbon receptor |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANKRD12 | ankyrin repeat domain 12 |
| APP | amyloid beta (A4) precursor protein |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATXN1 | ataxin 1 |
| BAGE | B melanoma antigen |
| BAX | BCL2-associated X protein |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BLVRA | biliverdin reductase A |
| BMP7 | bone morphogenetic protein 7 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CEP63 | centrosomal protein 63kDa |
| CFD | complement factor D (adipsin) |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CTTN | cortactin |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DTNA | dystrobrevin, alpha |
| DUSP22 | dual specificity phosphatase 22 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| ELMO3 | engulfment and cell motility 3 |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GOLGA2 | golgin A2 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HCFC1 | host cell factor C1 |
| HEATR3 | HEAT repeat containing 3 |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H2AJ | histone cluster 1, H2aj |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ING1 | inhibitor of growth family, member 1 |
| INTS1 | integrator complex subunit 1 |
| IRF9 | interferon regulatory factor 9 |
| KAT5 | K(lysine) acetyltransferase 5 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KLHL24 | kelch-like family member 24 |
| LOC100287590 | uncharacterized LOC100287590 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MZF1 | myeloid zinc finger 1 |
| NCDN | neurochondrin |
| NCSTN | nicastrin |
| NEK1 | NIMA-related kinase 1 |
| NEK2 | NIMA-related kinase 2 |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRDX2 | peroxiredoxin 2 |
| PVR | poliovirus receptor |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) |
| RAB27B | RAB27B, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RBM34 | RNA binding motif protein 34 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPS28 | ribosomal protein S28 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SIKE1 | suppressor of IKBKE 1 |
| SLC25A17 | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC38A7 | solute carrier family 38, member 7 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPN | sialophorin |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STAT5B | signal transducer and activator of transcription 5B |
| SUGP2 | SURP and G patch domain containing 2 |
| TFIP11 | tuftelin interacting protein 11 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TMED5 | transmembrane emp24 protein transport domain containing 5 |
| TOP3A | topoisomerase (DNA) III alpha |
| TPD52 | tumor protein D52 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRAPPC11 | trafficking protein particle complex 11 |
| UBAP1 | ubiquitin associated protein 1 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VARS | valyl-tRNA synthetase |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF254 | zinc finger protein 254 |
| ZNF318 | zinc finger protein 318 |
| ZNF451 | zinc finger protein 451 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANO10 | anoctamin 10 |
| ANXA6 | annexin A6 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARRB2 | arrestin, beta 2 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CD320 | CD320 molecule |
| CDCA4 | cell division cycle associated 4 |
| CDKN2AIP | CDKN2A interacting protein |
| CENPB | centromere protein B, 80kDa |
| CFAP20 | cilia and flagella associated protein 20 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COCH | cochlin |
| CPOX | coproporphyrinogen oxidase |
| CRBN | cereblon |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
| DENND5A | DENN/MADD domain containing 5A |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DPY19L4 | dpy-19-like 4 (C. elegans) |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EFNA4 | ephrin-A4 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERAL1 | Era-like 12S mitochondrial rRNA chaperone 1 |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FZD4 | frizzled class receptor 4 |
| GCA | grancalcin, EF-hand calcium binding protein |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GTPBP6 | GTP binding protein 6 (putative) |
| HIRIP3 | HIRA interacting protein 3 |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H3H | histone cluster 1, H3h |
| HOXC6 | homeobox C6 |
| IMMT | inner membrane protein, mitochondrial |
| KAT7 | K(lysine) acetyltransferase 7 |
| KLHDC3 | kelch domain containing 3 |
| KLHL12 | kelch-like family member 12 |
| KLHL21 | kelch-like family member 21 |
| LAP3 | leucine aminopeptidase 3 |
| LOC642236 | FSHD region gene 1 pseudogene |
| MAPK3 | mitogen-activated protein kinase 3 |
| MCRS1 | microspherule protein 1 |
| MICB | MHC class I polypeptide-related sequence B |
| MOCS3 | molybdenum cofactor synthesis 3 |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa |
| NEK4 | NIMA-related kinase 4 |
| NFS1 | NFS1 cysteine desulfurase |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NPY1R | neuropeptide Y receptor Y1 |
| PDLIM1 | PDZ and LIM domain 1 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PMVK | phosphomevalonate kinase |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 |
| PPT1 | palmitoyl-protein thioesterase 1 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| QARS | glutaminyl-tRNA synthetase |
| RAB17 | RAB17, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RBM38 | RNA binding motif protein 38 |
| RCOR3 | REST corepressor 3 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RSL24D1 | ribosomal L24 domain containing 1 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SPATA2L | spermatogenesis associated 2-like |
| SPATS2 | spermatogenesis associated, serine-rich 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBCCD1 | TBCC domain containing 1 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TMEM248 | transmembrane protein 248 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TSPAN13 | tetraspanin 13 |
| TSPO | translocator protein (18kDa) |
| TTC1 | tetratricopeptide repeat domain 1 |
| TTC27 | tetratricopeptide repeat domain 27 |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR44 | WD repeat domain 44 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF273 | zinc finger protein 273 |
| ZNF84 | zinc finger protein 84 |
