yohimbine-1763 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the yohimbine-1763 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACTC1 actin, alpha, cardiac muscle 1
ADAM8 ADAM metallopeptidase domain 8
AKAP10 A kinase (PRKA) anchor protein 10
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ARID4B AT rich interactive domain 4B (RBP1-like)
BAG3 BCL2-associated athanogene 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C14ORF93 chromosome 14 open reading frame 93
C4BPA complement component 4 binding protein, alpha
CA12 carbonic anhydrase XII
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DIO2 deiodinase, iodothyronine, type II
DMTN dematin actin binding protein
DOCK5 dedicator of cytokinesis 5
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
EGR4 early growth response 4
EHBP1 EH domain binding protein 1
EHD1 EH-domain containing 1
EML2 echinoderm microtubule associated protein like 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPOR erythropoietin receptor
EPX eosinophil peroxidase
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FMOD fibromodulin
FOXN3 forkhead box N3
FSCN3 fascin actin-bundling protein 3, testicular
GCDH glutaryl-CoA dehydrogenase
GIMAP5 GTPase, IMAP family member 5
GK glycerol kinase
GLRX3 glutaredoxin 3
GPHN gephyrin
GPR182 G protein-coupled receptor 182
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRK5 G protein-coupled receptor kinase 5
GRM6 glutamate receptor, metabotropic 6
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H4J histone cluster 1, H4j
HP haptoglobin
HPS1 Hermansky-Pudlak syndrome 1
HR hair growth associated
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
MAP4 microtubule-associated protein 4
MAST2 microtubule associated serine/threonine kinase 2
MED9 mediator complex subunit 9
MPV17 MpV17 mitochondrial inner membrane protein
MTERF4 mitochondrial transcription termination factor 4
NEFH neurofilament, heavy polypeptide
NPEPL1 aminopeptidase-like 1
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PDIA4 protein disulfide isomerase family A, member 4
PDLIM1 PDZ and LIM domain 1
PFN2 profilin 2
PGC progastricsin (pepsinogen C)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PRDM4 PR domain containing 4
PSIP1 PC4 and SFRS1 interacting protein 1
RAB3A RAB3A, member RAS oncogene family
RNASE3 ribonuclease, RNase A family, 3
S100A8 S100 calcium binding protein A8
SBF1 SET binding factor 1
SEC23IP SEC23 interacting protein
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SGSM3 small G protein signaling modulator 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMG5 SMG5 nonsense mediated mRNA decay factor
SMIM8 small integral membrane protein 8
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPA17 sperm autoantigenic protein 17
SPDEF SAM pointed domain containing ETS transcription factor
SPN sialophorin
SPRY4 sprouty homolog 4 (Drosophila)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRCAP Snf2-related CREBBP activator protein
TBC1D2B TBC1 domain family, member 2B
TJAP1 tight junction associated protein 1 (peripheral)
TLR4 toll-like receptor 4
TMOD1 tropomodulin 1
TUBGCP2 tubulin, gamma complex associated protein 2
TXNL4A thioredoxin-like 4A
UBE2O ubiquitin-conjugating enzyme E2O
UNC13B unc-13 homolog B (C. elegans)
USO1 USO1 vesicle transport factor
VAC14 Vac14 homolog (S. cerevisiae)
WDR44 WD repeat domain 44
WIPI1 WD repeat domain, phosphoinositide interacting 1
WSB1 WD repeat and SOCS box containing 1
WWC2 WW and C2 domain containing 2
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF408 zinc finger protein 408
ZNF589 zinc finger protein 589
ZNF669 zinc finger protein 669

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD3 abhydrolase domain containing 3
ACIN1 apoptotic chromatin condensation inducer 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ASCC1 activating signal cointegrator 1 complex subunit 1
ATXN2 ataxin 2
BCKDK branched chain ketoacid dehydrogenase kinase
C11ORF68 chromosome 11 open reading frame 68
C14ORF159 chromosome 14 open reading frame 159
C5ORF30 chromosome 5 open reading frame 30
CCDC6 coiled-coil domain containing 6
CCNT1 cyclin T1
CD101 CD101 molecule
CD151 CD151 molecule (Raph blood group)
CD302 CD302 molecule
CD48 CD48 molecule
CD81 CD81 molecule
CDCA3 cell division cycle associated 3
CLASP1 cytoplasmic linker associated protein 1
CLASRP CLK4-associating serine/arginine rich protein
CSK c-src tyrosine kinase
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DPYD dihydropyrimidine dehydrogenase
DPYSL2 dihydropyrimidinase-like 2
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DYNLL1 dynein, light chain, LC8-type 1
EMD emerin
ENDOG endonuclease G
EXOSC9 exosome component 9
FAM188A family with sequence similarity 188, member A
FAM222B family with sequence similarity 222, member B
FAM46A family with sequence similarity 46, member A
FBXL4 F-box and leucine-rich repeat protein 4
FPGS folylpolyglutamate synthase
GPATCH2 G patch domain containing 2
GPR183 G protein-coupled receptor 183
HACD2 3-hydroxyacyl-CoA dehydratase 2
HARS histidyl-tRNA synthetase
IGKV1D-13 immunoglobulin kappa variable 1D-13
KDM3A lysine (K)-specific demethylase 3A
KIAA0894 KIAA0894 protein
KIF18A kinesin family member 18A
KIF1BP KIF1 binding protein
KIFAP3 kinesin-associated protein 3
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAGOHB mago-nashi homolog B (Drosophila)
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPK3 mitogen-activated protein kinase 3
MCM10 minichromosome maintenance complex component 10
METTL21B methyltransferase like 21B
METTL22 methyltransferase like 22
MPDU1 mannose-P-dolichol utilization defect 1
MRPL28 mitochondrial ribosomal protein L28
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NCF2 neutrophil cytosolic factor 2
NRBP1 nuclear receptor binding protein 1
NUP93 nucleoporin 93kDa
OIP5 Opa interacting protein 5
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PELI1 pellino E3 ubiquitin protein ligase 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRMT3 protein arginine methyltransferase 3
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTH2R parathyroid hormone 2 receptor
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RARS arginyl-tRNA synthetase
RBBP7 retinoblastoma binding protein 7
RBM47 RNA binding motif protein 47
RMDN3 regulator of microtubule dynamics 3
ROGDI rogdi homolog (Drosophila)
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RSF1 remodeling and spacing factor 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIRT6 sirtuin 6
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
STARD3 StAR-related lipid transfer (START) domain containing 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D31 TBC1 domain family, member 31
TMEM135 transmembrane protein 135
TMEM14A transmembrane protein 14A
TMEM165 transmembrane protein 165
TOE1 target of EGR1, member 1 (nuclear)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TSC22D1 TSC22 domain family, member 1
TUBA3D tubulin, alpha 3d
TXLNA taxilin alpha
UBAC1 UBA domain containing 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
WDR82 WD repeat domain 82
YEATS2 YEATS domain containing 2
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF426 zinc finger protein 426
ZNF652 zinc finger protein 652