| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the yohimbine-2755 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI2 | abl-interactor 2 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APC | adenomatous polyposis coli |
| APOM | apolipoprotein M |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASPH | aspartate beta-hydroxylase |
| ATF7 | activating transcription factor 7 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTG2 | BTG family, member 2 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CACYBP | calcyclin binding protein |
| CAPN2 | calpain 2, (m/II) large subunit |
| CLEC4E | C-type lectin domain family 4, member E |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CSTA | cystatin A (stefin A) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DLX2 | distal-less homeobox 2 |
| DOCK6 | dedicator of cytokinesis 6 |
| EFNA3 | ephrin-A3 |
| EGFR | epidermal growth factor receptor |
| EHD1 | EH-domain containing 1 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| EXT1 | exostosin glycosyltransferase 1 |
| FHL1 | four and a half LIM domains 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR22 | G protein-coupled receptor 22 |
| GRB10 | growth factor receptor-bound protein 10 |
| GRPR | gastrin-releasing peptide receptor |
| GSK3A | glycogen synthase kinase 3 alpha |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H4E | histone cluster 1, H4e |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGA6 | integrin, alpha 6 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0232 | KIAA0232 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MEF2D | myocyte enhancer factor 2D |
| METTL16 | methyltransferase like 16 |
| METTL7A | methyltransferase like 7A |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| OGG1 | 8-oxoguanine DNA glycosylase |
| PEX1 | peroxisomal biogenesis factor 1 |
| PHF14 | PHD finger protein 14 |
| PLAU | plasminogen activator, urokinase |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PTK6 | protein tyrosine kinase 6 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RETN | resistin |
| RFPL3 | ret finger protein-like 3 |
| RFXAP | regulatory factor X-associated protein |
| RGCC | regulator of cell cycle |
| RGS3 | regulator of G-protein signaling 3 |
| RNF39 | ring finger protein 39 |
| S100A8 | S100 calcium binding protein A8 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SIRT5 | sirtuin 5 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SOAT2 | sterol O-acyltransferase 2 |
| SSTR4 | somatostatin receptor 4 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STK17B | serine/threonine kinase 17b |
| STK4 | serine/threonine kinase 4 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBXA2R | thromboxane A2 receptor |
| TDRKH | tudor and KH domain containing |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THBS1 | thrombospondin 1 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TRADD | TNFRSF1A-associated via death domain |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| VIM | vimentin |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF286A | zinc finger protein 286A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AMT | aminomethyltransferase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARMC4 | armadillo repeat containing 4 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBX4 | chromobox homolog 4 |
| CCDC68 | coiled-coil domain containing 68 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHKB | choline kinase beta |
| CORT | cortistatin |
| CST6 | cystatin E/M |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERO1L | ERO1-like (S. cerevisiae) |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM76A | family with sequence similarity 76, member A |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FGF23 | fibroblast growth factor 23 |
| FLT4 | fms-related tyrosine kinase 4 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| FZD4 | frizzled class receptor 4 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAN | gigaxonin |
| GLB1L | galactosidase, beta 1-like |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR21 | G protein-coupled receptor 21 |
| HDAC11 | histone deacetylase 11 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| JMJD4 | jumonji domain containing 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLHL25 | kelch-like family member 25 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| MBTD1 | mbt domain containing 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| NPTX2 | neuronal pentraxin II |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| ONECUT2 | one cut homeobox 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PKN1 | protein kinase N1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PODXL2 | podocalyxin-like 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RIN2 | Ras and Rab interactor 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| S100A2 | S100 calcium binding protein A2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIRT2 | sirtuin 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC12A9 | solute carrier family 12, member 9 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPRYD7 | SPRY domain containing 7 |
| TCTN2 | tectonic family member 2 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMC7 | transmembrane channel-like 7 |
| TRIM25 | tripartite motif containing 25 |
| TSPYL2 | TSPY-like 2 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| XAB2 | XPA binding protein 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF205 | zinc finger protein 205 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF862 | zinc finger protein 862 |
