| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the yohimbine-6777 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A2M | alpha-2-macroglobulin |
| ADCY1 | adenylate cyclase 1 (brain) |
| ADRB3 | adrenoceptor beta 3 |
| AMT | aminomethyltransferase |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C3 | complement component 3 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CABP2 | calcium binding protein 2 |
| CCDC88C | coiled-coil domain containing 88C |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTBP2 | C-terminal binding protein 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CTSZ | cathepsin Z |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUSP13 | dual specificity phosphatase 13 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EHD2 | EH-domain containing 2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ETV6 | ets variant 6 |
| FADS2 | fatty acid desaturase 2 |
| FAM155A | family with sequence similarity 155, member A |
| FBLN1 | fibulin 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GPR161 | G protein-coupled receptor 161 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GSPT1 | G1 to S phase transition 1 |
| HFE | hemochromatosis |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HRASLS2 | HRAS-like suppressor 2 |
| IFT27 | intraflagellar transport 27 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIAA0754 | KIAA0754 |
| KLHL22 | kelch-like family member 22 |
| KLHL35 | kelch-like family member 35 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LOC157562 | uncharacterized LOC157562 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRC75B | leucine rich repeat containing 75B |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MMP19 | matrix metallopeptidase 19 |
| MSI1 | musashi RNA-binding protein 1 |
| MT3 | metallothionein 3 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYO10 | myosin X |
| OPRL1 | opiate receptor-like 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PCDHA9 | protocadherin alpha 9 |
| PDLIM5 | PDZ and LIM domain 5 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLIN2 | perilipin 2 |
| PLK3 | polo-like kinase 3 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa |
| POU4F2 | POU class 4 homeobox 2 |
| PTK6 | protein tyrosine kinase 6 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RGS12 | regulator of G-protein signaling 12 |
| RGS5 | regulator of G-protein signaling 5 |
| RND2 | Rho family GTPase 2 |
| RPGRIP1L | RPGRIP1-like |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SHOX2 | short stature homeobox 2 |
| SKIL | SKI-like proto-oncogene |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| TAOK1 | TAO kinase 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| UNC13A | unc-13 homolog A (C. elegans) |
| VASH2 | vasohibin 2 |
| VAX2 | ventral anterior homeobox 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WDR62 | WD repeat domain 62 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZNF606 | zinc finger protein 606 |
| ZNF804A | zinc finger protein 804A |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACP2 | acid phosphatase 2, lysosomal |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APOD | apolipoprotein D |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARRB1 | arrestin, beta 1 |
| BAX | BCL2-associated X protein |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPRIN2 | caprin family member 2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD302 | CD302 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CFAP44 | cilia and flagella associated protein 44 |
| CLDN15 | claudin 15 |
| CRY2 | cryptochrome circadian clock 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNM1 | dynamin 1 |
| DSE | dermatan sulfate epimerase |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM184A | family with sequence similarity 184, member A |
| FAM188A | family with sequence similarity 188, member A |
| FAM50B | family with sequence similarity 50, member B |
| FKBP5 | FK506 binding protein 5 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GATA4 | GATA binding protein 4 |
| GPX2 | glutathione peroxidase 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HMOX1 | heme oxygenase 1 |
| HOXC8 | homeobox C8 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT22 | intraflagellar transport 22 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL21 | kelch-like family member 21 |
| LAMA3 | laminin, alpha 3 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MEFV | Mediterranean fever |
| MEIS1 | Meis homeobox 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCDH12 | protocadherin 12 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRR7 | proline rich 7 (synaptic) |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RNF121 | ring finger protein 121 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPATA7 | spermatogenesis associated 7 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TEP1 | telomerase-associated protein 1 |
| THBS3 | thrombospondin 3 |
| TMC5 | transmembrane channel-like 5 |
| TMEM183A | transmembrane protein 183A |
| TRABD | TraB domain containing |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSPYL2 | TSPY-like 2 |
| TUBA3C | tubulin, alpha 3c |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| YIPF3 | Yip1 domain family, member 3 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF184 | zinc finger protein 184 |
| ZNF286A | zinc finger protein 286A |
| ZNF324 | zinc finger protein 324 |
| ZNF573 | zinc finger protein 573 |
| ZNF675 | zinc finger protein 675 |
| ZNF701 | zinc finger protein 701 |
| ZNF813 | zinc finger protein 813 |
| ZNF85 | zinc finger protein 85 |