yohimbine-6777 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the yohimbine-6777 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
A2M alpha-2-macroglobulin
ADCY1 adenylate cyclase 1 (brain)
ADRB3 adrenoceptor beta 3
AMT aminomethyltransferase
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCAM basal cell adhesion molecule (Lutheran blood group)
BLZF1 basic leucine zipper nuclear factor 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C11ORF63 chromosome 11 open reading frame 63
C17ORF59 chromosome 17 open reading frame 59
C3 complement component 3
C5ORF45 chromosome 5 open reading frame 45
CABP2 calcium binding protein 2
CCDC88C coiled-coil domain containing 88C
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
COL11A2 collagen, type XI, alpha 2
COL6A1 collagen, type VI, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRIP1 cysteine-rich protein 1 (intestinal)
CTBP2 C-terminal binding protein 2
CTIF CBP80/20-dependent translation initiation factor
CTSZ cathepsin Z
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DTX2 deltex 2, E3 ubiquitin ligase
DUSP13 dual specificity phosphatase 13
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHD2 EH-domain containing 2
EPHX2 epoxide hydrolase 2, cytoplasmic
ETV6 ets variant 6
FADS2 fatty acid desaturase 2
FAM155A family with sequence similarity 155, member A
FBLN1 fibulin 1
FLJ11710 uncharacterized protein FLJ11710
FUT2 fucosyltransferase 2 (secretor status included)
GPR161 G protein-coupled receptor 161
GREB1 growth regulation by estrogen in breast cancer 1
GSPT1 G1 to S phase transition 1
HFE hemochromatosis
HLA-DOA major histocompatibility complex, class II, DO alpha
HRASLS2 HRAS-like suppressor 2
IFT27 intraflagellar transport 27
IGFBP5 insulin-like growth factor binding protein 5
IGLJ3 immunoglobulin lambda joining 3
INPP5J inositol polyphosphate-5-phosphatase J
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KDM4B lysine (K)-specific demethylase 4B
KIAA0754 KIAA0754
KLHL22 kelch-like family member 22
KLHL35 kelch-like family member 35
LAMP3 lysosomal-associated membrane protein 3
LOC157562 uncharacterized LOC157562
LRP12 low density lipoprotein receptor-related protein 12
LRRC75B leucine rich repeat containing 75B
MCF2L MCF.2 cell line derived transforming sequence-like
MMP19 matrix metallopeptidase 19
MSI1 musashi RNA-binding protein 1
MT3 metallothionein 3
MYH14 myosin, heavy chain 14, non-muscle
MYO10 myosin X
OPRL1 opiate receptor-like 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDHA9 protocadherin alpha 9
PDLIM5 PDZ and LIM domain 5
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLIN2 perilipin 2
PLK3 polo-like kinase 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POU4F2 POU class 4 homeobox 2
PTK6 protein tyrosine kinase 6
PTPRM protein tyrosine phosphatase, receptor type, M
RGS12 regulator of G-protein signaling 12
RGS5 regulator of G-protein signaling 5
RND2 Rho family GTPase 2
RPGRIP1L RPGRIP1-like
SAYSD1 SAYSVFN motif domain containing 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERGEF secretion regulating guanine nucleotide exchange factor
SHOX2 short stature homeobox 2
SKIL SKI-like proto-oncogene
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC39A9 solute carrier family 39, member 9
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TAOK1 TAO kinase 1
TIMP3 TIMP metallopeptidase inhibitor 3
UNC13A unc-13 homolog A (C. elegans)
VASH2 vasohibin 2
VAX2 ventral anterior homeobox 2
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZNF606 zinc finger protein 606
ZNF804A zinc finger protein 804A

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ACP2 acid phosphatase 2, lysosomal
ACSF2 acyl-CoA synthetase family member 2
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOD apolipoprotein D
APOLD1 apolipoprotein L domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARRB1 arrestin, beta 1
BAX BCL2-associated X protein
BGLAP bone gamma-carboxyglutamate (gla) protein
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CAPRIN2 caprin family member 2
CCP110 centriolar coiled coil protein 110kDa
CD302 CD302 molecule
CDK20 cyclin-dependent kinase 20
CFAP44 cilia and flagella associated protein 44
CLDN15 claudin 15
CRY2 cryptochrome circadian clock 2
DNAL4 dynein, axonemal, light chain 4
DNM1 dynamin 1
DSE dermatan sulfate epimerase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGLN3 egl-9 family hypoxia-inducible factor 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM184A family with sequence similarity 184, member A
FAM188A family with sequence similarity 188, member A
FAM50B family with sequence similarity 50, member B
FKBP5 FK506 binding protein 5
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS2 fibroblast growth factor receptor substrate 2
FSD1 fibronectin type III and SPRY domain containing 1
GATA4 GATA binding protein 4
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IFT22 intraflagellar transport 22
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KLHL21 kelch-like family member 21
LAMA3 laminin, alpha 3
LGALS4 lectin, galactoside-binding, soluble, 4
LINC00115 long intergenic non-protein coding RNA 115
LMO2 LIM domain only 2 (rhombotin-like 1)
MAST3 microtubule associated serine/threonine kinase 3
MATK megakaryocyte-associated tyrosine kinase
MEFV Mediterranean fever
MEIS1 Meis homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
NDE1 nudE neurodevelopment protein 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NHEJ1 nonhomologous end-joining factor 1
NT5E 5'-nucleotidase, ecto (CD73)
NUP62CL nucleoporin 62kDa C-terminal like
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH12 protocadherin 12
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRR7 proline rich 7 (synaptic)
R3HCC1L R3H domain and coiled-coil containing 1-like
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RNF121 ring finger protein 121
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRAL2 SIR2 antiphage like 2
SLIT2 slit homolog 2 (Drosophila)
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMR3A submaxillary gland androgen regulated protein 3A
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
SPATA7 spermatogenesis associated 7
STARD5 StAR-related lipid transfer (START) domain containing 5
TEP1 telomerase-associated protein 1
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TMEM183A transmembrane protein 183A
TRABD TraB domain containing
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
YIPF3 Yip1 domain family, member 3
ZBTB22 zinc finger and BTB domain containing 22
ZNF184 zinc finger protein 184
ZNF286A zinc finger protein 286A
ZNF324 zinc finger protein 324
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675
ZNF701 zinc finger protein 701
ZNF813 zinc finger protein 813
ZNF85 zinc finger protein 85