| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the yohimbine-7130 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ADCK2 | aarF domain containing kinase 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANKRD12 | ankyrin repeat domain 12 |
| APH1B | APH1B gamma secretase subunit |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| BCAS3 | breast carcinoma amplified sequence 3 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8A | complement component 8, alpha polypeptide |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD58 | CD58 molecule |
| CEP112 | centrosomal protein 112kDa |
| CEP162 | centrosomal protein 162kDa |
| CHMP6 | charged multivesicular body protein 6 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLSPN | claspin |
| CNTNAP2 | contactin associated protein-like 2 |
| CTSK | cathepsin K |
| DSCAM | Down syndrome cell adhesion molecule |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNA1 | ephrin-A1 |
| EN2 | engrailed homeobox 2 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FKBP5 | FK506 binding protein 5 |
| FLOT2 | flotillin 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| HLX | H2.0-like homeobox |
| HNF1B | HNF1 homeobox B |
| HOMER2 | homer scaffolding protein 2 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KIAA0922 | KIAA0922 |
| KIF1A | kinesin family member 1A |
| KLF2 | Kruppel-like factor 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT34 | keratin 34, type I |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MPPE1 | metallophosphoesterase 1 |
| MTA1 | metastasis associated 1 |
| MTMR12 | myotubularin related protein 12 |
| MTMR7 | myotubularin related protein 7 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NF2 | neurofibromin 2 (merlin) |
| NLRX1 | NLR family member X1 |
| NOL10 | nucleolar protein 10 |
| NPR3 | natriuretic peptide receptor 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRRC2A | proline-rich coiled-coil 2A |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB2A | RAB2A, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RANBP3 | RAN binding protein 3 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RIN1 | Ras and Rab interactor 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNFT2 | ring finger protein, transmembrane 2 |
| SBF1 | SET binding factor 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SGSM2 | small G protein signaling modulator 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| SSH3 | slingshot protein phosphatase 3 |
| ST20 | suppressor of tumorigenicity 20 |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like |
| TBC1D22A | TBC1 domain family, member 22A |
| TBC1D4 | TBC1 domain family, member 4 |
| TTC12 | tetratricopeptide repeat domain 12 |
| USP19 | ubiquitin specific peptidase 19 |
| WDR37 | WD repeat domain 37 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF350 | zinc finger protein 350 |
| ZNF510 | zinc finger protein 510 |
| ZNF839 | zinc finger protein 839 |
| Symbol | Name |
|---|---|
| ACTN4 | actinin, alpha 4 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| AGO3 | argonaute RISC catalytic component 3 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| BAK1 | BCL2-antagonist/killer 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) |
| BCL9 | B-cell CLL/lymphoma 9 |
| BFAR | bifunctional apoptosis regulator |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CHPF | chondroitin polymerizing factor |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CTSV | cathepsin V |
| CXORF56 | chromosome X open reading frame 56 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EDC3 | enhancer of mRNA decapping 3 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EVPL | envoplakin |
| FADS2 | fatty acid desaturase 2 |
| FAM155A | family with sequence similarity 155, member A |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FOXD1 | forkhead box D1 |
| FPGS | folylpolyglutamate synthase |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GMIP | GEM interacting protein |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HIST1H1D | histone cluster 1, H1d |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| KIRREL | kin of IRRE like (Drosophila) |
| KPTN | kaptin (actin binding protein) |
| KRT4 | keratin 4, type II |
| KRT6A | keratin 6A, type II |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NABP2 | nucleic acid binding protein 2 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSTM1 | osteopetrosis associated transmembrane protein 1 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLD2 | phospholipase D2 |
| POLH | polymerase (DNA directed), eta |
| POLM | polymerase (DNA directed), mu |
| POMT1 | protein-O-mannosyltransferase 1 |
| POU2F1 | POU class 2 homeobox 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRR3 | proline rich 3 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PYCARD | PYD and CARD domain containing |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RHOB | ras homolog family member B |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| S100A14 | S100 calcium binding protein A14 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SETD1B | SET domain containing 1B |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STK16 | serine/threonine kinase 16 |
| STX1A | syntaxin 1A (brain) |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| THOC6 | THO complex 6 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TOR4A | torsin family 4, member A |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM21 | tripartite motif containing 21 |
| TUBA3D | tubulin, alpha 3d |
| UBXN6 | UBX domain protein 6 |
| UNKL | unkempt family zinc finger-like |
| ZNF107 | zinc finger protein 107 |
| ZNF112 | zinc finger protein 112 |
| ZNF212 | zinc finger protein 212 |
| ZNF770 | zinc finger protein 770 |
| ZNF787 | zinc finger protein 787 |
| ZXDC | ZXD family zinc finger C |
