z disc Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached. (Gene Ontology, GO_0030018)
Similar Terms
Downloads & Tools

Genes

94 proteins localized to the z disc cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
FHOD3 formin homology 2 domain containing 3 0.663342
DES desmin 0.663342
PALLD palladin, cytoskeletal associated protein 0.663342
NEBL nebulette 0.663342
DST dystonin 0.663342
MYOT myotilin 0.663342
FBP2 fructose-1,6-bisphosphatase 2 0.663342
FRG1 FSHD region gene 1 0.663342
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 0.663342
SYNE2 spectrin repeat containing, nuclear envelope 2 0.663342
FLNB filamin B, beta 0.663342
NEB nebulin 0.663342
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.663342
SORBS2 sorbin and SH3 domain containing 2 0.663342
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.663342
PARVB parvin, beta 0.663342
ACTN2 actinin, alpha 2 0.663342
LDB3 LIM domain binding 3 0.663342
SYNE1 spectrin repeat containing, nuclear envelope 1 0.663342
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.237908
HRC histidine rich calcium binding protein 0.237908
NEXN nexilin (F actin binding protein) 0.237908
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.237908
TTN titin 0.237908
MYOZ2 myozenin 2 0.237908
SRI sorcin 0.237908
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.237908
FKBP1A FK506 binding protein 1A, 12kDa 0.237908
CAPN3 calpain 3, (p94) 0.237908
TCAP titin-cap 0.237908
BMP10 bone morphogenetic protein 10 0.237908
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.237908
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.237908
OBSL1 obscurin-like 1 0.237908
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.237908
KY kyphoscoliosis peptidase 0.237908
SYNPO2 synaptopodin 2 0.237908
AHNAK2 AHNAK nucleoprotein 2 0.098109
PSEN2 presenilin 2 0.098109
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.098109
PSEN1 presenilin 1 0.098109
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.098109
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.098109
ANK2 ankyrin 2, neuronal 0.098109
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.098109
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.098109
RYR2 ryanodine receptor 2 (cardiac) 0.098109
PDE4B phosphodiesterase 4B, cAMP-specific 0.098109
SCN1A sodium channel, voltage gated, type I alpha subunit 0.098109
SCN3B sodium channel, voltage gated, type III beta subunit 0.098109
CASQ2 calsequestrin 2 (cardiac muscle) 0.098109
JUP junction plakoglobin 0.098109
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.098109
BIN1 bridging integrator 1 0.098109
PGM5 phosphoglucomutase 5 0.098109
FHL3 four and a half LIM domains 3 0.03318
MYPN myopalladin 0.03318
XIRP2 xin actin binding repeat containing 2 0.03318
SPHKAP SPHK1 interactor, AKAP domain containing 0.03318
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.03318
FHL2 four and a half LIM domains 2 0.03318
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.03318
CRYAB crystallin, alpha B 0.03318
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.03318
ACTN4 actinin, alpha 4 0.03318
ACTN1 actinin, alpha 1 0.03318
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.03318
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.03318
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.03318
MURC muscle-related coiled-coil protein 0.03318
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.03318
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.03318
AKAP4 A kinase (PRKA) anchor protein 4 0.03318
GLRX3 glutaredoxin 3 0.03318
HDAC4 histone deacetylase 4 0.03318
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 0.03318
MYL9 myosin, light chain 9, regulatory 0.03318
JPH2 junctophilin 2 0.03318
JPH1 junctophilin 1 0.03318
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.03318
ANK1 ankyrin 1, erythrocytic 0.03318
ADRA1A adrenoceptor alpha 1A 0.03318
CAPZB capping protein (actin filament) muscle Z-line, beta 0.03318
S100A1 S100 calcium binding protein A1 0.03318
MYL12B myosin, light chain 12B, regulatory 0.03318
SYNC syncoilin, intermediate filament protein 0.03318
KRT8 keratin 8, type II 0.03318
HOMER1 homer scaffolding protein 1 0.03318
SYNPO2L synaptopodin 2-like 0.03318
FBXO32 F-box protein 32 0.03318
KRT19 keratin 19, type I 0.03318
HSPB1 heat shock 27kDa protein 1 0.03318
BAG3 BCL2-associated athanogene 3 0.03318
MYOZ3 myozenin 3 0.03318