z disc Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached. (Gene Ontology, GO_0030018)
External Link http://amigo.geneontology.org/amigo/term/GO:0030018
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Genes

103 proteins localized to the z disc cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
ACTN1 actinin, alpha 1
ACTN2 actinin, alpha 2
ACTN4 actinin, alpha 4
ADRA1A adrenoceptor alpha 1A
AHNAK2 AHNAK nucleoprotein 2
AKAP4 A kinase (PRKA) anchor protein 4
ANK1 ankyrin 1, erythrocytic
ANK2 ankyrin 2, neuronal
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAG3 BCL2-associated athanogene 3
BIN1 bridging integrator 1
BMP10 bone morphogenetic protein 10
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CAPN3 calpain 3, (p94)
CASQ2 calsequestrin 2 (cardiac muscle)
CAV3 caveolin 3
CRYAB crystallin, alpha B
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DES desmin
DMD dystrophin
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DST dystonin
FBP2 fructose-1,6-bisphosphatase 2
FBXL22 F-box and leucine-rich repeat protein 22
FBXO22 F-box protein 22
FBXO32 F-box protein 32
FHL2 four and a half LIM domains 2
FHL3 four and a half LIM domains 3
FHOD3 formin homology 2 domain containing 3
FKBP1A FK506 binding protein 1A, 12kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLNB filamin B, beta
FLNC filamin C, gamma
FRG1 FSHD region gene 1
GLRX3 glutaredoxin 3
HDAC4 histone deacetylase 4
HOMER1 homer scaffolding protein 1
HRC histidine rich calcium binding protein
HSPB1 heat shock 27kDa protein 1
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
JPH1 junctophilin 1
JPH2 junctophilin 2
JUP junction plakoglobin
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KRT19 keratin 19, type I
KRT8 keratin 8, type II
KY kyphoscoliosis peptidase
LDB3 LIM domain binding 3
MURC muscle-related coiled-coil protein
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL12B myosin, light chain 12B, regulatory
MYL9 myosin, light chain 9, regulatory
MYOT myotilin
MYOZ2 myozenin 2
MYOZ3 myozenin 3
MYPN myopalladin
NEB nebulin
NEBL nebulette
NEXN nexilin (F actin binding protein)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OBSL1 obscurin-like 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PALLD palladin, cytoskeletal associated protein
PARVA parvin, alpha
PARVB parvin, beta
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM3 PDZ and LIM domain 3
PDLIM5 PDZ and LIM domain 5
PGM5 phosphoglucomutase 5
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PSEN1 presenilin 1
PSEN2 presenilin 2
RYR2 ryanodine receptor 2 (cardiac)
S100A1 S100 calcium binding protein A1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SORBS2 sorbin and SH3 domain containing 2
SPHKAP SPHK1 interactor, AKAP domain containing
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRI sorcin
SYNC syncoilin, intermediate filament protein
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNPO2 synaptopodin 2
SYNPO2L synaptopodin 2-like
TCAP titin-cap
TRIM54 tripartite motif containing 54
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TTN titin
XIRP2 xin actin binding repeat containing 2