zalcitabine-2932 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the zalcitabine-2932 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM20 ADAM metallopeptidase domain 20
ANGEL2 angel homolog 2 (Drosophila)
ARHGAP26 Rho GTPase activating protein 26
ARMC4 armadillo repeat containing 4
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ATG10 autophagy related 10
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATXN3 ataxin 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BTBD7 BTB (POZ) domain containing 7
C11ORF16 chromosome 11 open reading frame 16
C14ORF93 chromosome 14 open reading frame 93
C1ORF159 chromosome 1 open reading frame 159
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAV2 caveolin 2
CD34 CD34 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CPA2 carboxypeptidase A2 (pancreatic)
CRYL1 crystallin, lambda 1
CSRP2 cysteine and glycine-rich protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLC1 DLC1 Rho GTPase activating protein
DLG4 discs, large homolog 4 (Drosophila)
DOCK6 dedicator of cytokinesis 6
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EXOSC2 exosome component 2
EXTL3 exostosin-like glycosyltransferase 3
F12 coagulation factor XII (Hageman factor)
FADS3 fatty acid desaturase 3
FER1L4 fer-1-like family member 4, pseudogene (functional)
FLJ11292
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAS GNAS complex locus
GPRC5A G protein-coupled receptor, class C, group 5, member A
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HOMER3 homer scaffolding protein 3
HOXD1 homeobox D1
IGHMBP2 immunoglobulin mu binding protein 2
ITSN1 intersectin 1 (SH3 domain protein)
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCTD2 potassium channel tetramerization domain containing 2
KLF2 Kruppel-like factor 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LPAR2 lysophosphatidic acid receptor 2
LPPR1 lipid phosphate phosphatase-related protein type 1
MARC1 mitochondrial amidoxime reducing component 1
MED6 mediator complex subunit 6
METRN meteorin, glial cell differentiation regulator
MFSD6 major facilitator superfamily domain containing 6
MMP19 matrix metallopeptidase 19
MTCL1 microtubule crosslinking factor 1
MYOF myoferlin
NCAM1 neural cell adhesion molecule 1
NF2 neurofibromin 2 (merlin)
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOV nephroblastoma overexpressed
NPFF neuropeptide FF-amide peptide precursor
NPTX2 neuronal pentraxin II
OLFML2A olfactomedin-like 2A
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDE4DIP phosphodiesterase 4D interacting protein
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTCRA pre T-cell antigen receptor alpha
RNASE3 ribonuclease, RNase A family, 3
RPP25 ribonuclease P/MRP 25kDa subunit
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC14L1 SEC14-like 1 (S. cerevisiae)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SORBS3 sorbin and SH3 domain containing 3
SP140 SP140 nuclear body protein
SPATA20 spermatogenesis associated 20
SPTBN1 spectrin, beta, non-erythrocytic 1
ST7L suppression of tumorigenicity 7 like
STK24 serine/threonine kinase 24
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBCD tubulin folding cofactor D
TBX6 T-box 6
TIMELESS timeless circadian clock
TMEM255A transmembrane protein 255A
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRIL TLR4 interactor with leucine-rich repeats
ZNF574 zinc finger protein 574

decreased expression

Symbol Name
ACP2 acid phosphatase 2, lysosomal
ANXA3 annexin A3
ARID4A AT rich interactive domain 4A (RBP1-like)
ARRB1 arrestin, beta 1
ASB7 ankyrin repeat and SOCS box containing 7
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C17ORF80 chromosome 17 open reading frame 80
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC186 coiled-coil domain containing 186
CCNB1 cyclin B1
CD320 CD320 molecule
CD38 CD38 molecule
CDC20 cell division cycle 20
CDCA3 cell division cycle associated 3
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CEP72 centrosomal protein 72kDa
CFP complement factor properdin
CKAP5 cytoskeleton associated protein 5
CSNK1G3 casein kinase 1, gamma 3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DCAF17 DDB1 and CUL4 associated factor 17
DEPDC1 DEP domain containing 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
ECT2 epithelial cell transforming 2
ERCC2 excision repair cross-complementation group 2
FER fer (fps/fes related) tyrosine kinase
GEMIN8 gem (nuclear organelle) associated protein 8
GPATCH3 G patch domain containing 3
GRAMD1B GRAM domain containing 1B
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AC histone cluster 1, H2ac
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BG histone cluster 1, H2bg
HIST1H3H histone cluster 1, H3h
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA1 homeobox A1
HYAL2 hyaluronoglucosaminidase 2
IFI6 interferon, alpha-inducible protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL18 interleukin 18
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
JUNB jun B proto-oncogene
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
KIF24 kinesin family member 24
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LNPEP leucyl/cystinyl aminopeptidase
LOC729164 hCG1732469
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MANSC1 MANSC domain containing 1
MCOLN1 mucolipin 1
METTL16 methyltransferase like 16
MICA MHC class I polypeptide-related sequence A
MKL2 MKL/myocardin-like 2
MMP2 matrix metallopeptidase 2
MTMR12 myotubularin related protein 12
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NT5M 5',3'-nucleotidase, mitochondrial
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARPBP PARP1 binding protein
PCNXL4 pecanex-like 4 (Drosophila)
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLK1 polo-like kinase 1
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PSRC1 proline/serine-rich coiled-coil 1
PYGB phosphorylase, glycogen; brain
QSER1 glutamine and serine rich 1
QTRT1 queuine tRNA-ribosyltransferase 1
RFXAP regulatory factor X-associated protein
RIN1 Ras and Rab interactor 1
RNF121 ring finger protein 121
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGCE sarcoglycan, epsilon
SLC16A4 solute carrier family 16, member 4
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SP1 Sp1 transcription factor
STRN striatin, calmodulin binding protein
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYCP2 synaptonemal complex protein 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THAP10 THAP domain containing 10
THOP1 thimet oligopeptidase 1
TLR6 toll-like receptor 6
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM184B transmembrane protein 184B
TRABD TraB domain containing
TRDMT1 tRNA aspartic acid methyltransferase 1
UBE2S ubiquitin-conjugating enzyme E2S
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
ZNF141 zinc finger protein 141
ZNF280D zinc finger protein 280D
ZNF8 zinc finger protein 8