| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the zaprinast-1611 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANAPC10 | anaphase promoting complex subunit 10 |
| ANKRD12 | ankyrin repeat domain 12 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATP9B | ATPase, class II, type 9B |
| ATXN7 | ataxin 7 |
| BAG5 | BCL2-associated athanogene 5 |
| BCAP29 | B-cell receptor-associated protein 29 |
| BPI | bactericidal/permeability-increasing protein |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CANT1 | calcium activated nucleotidase 1 |
| CCNG2 | cyclin G2 |
| CCNT2 | cyclin T2 |
| CDCA3 | cell division cycle associated 3 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CPOX | coproporphyrinogen oxidase |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CYB561 | cytochrome b561 |
| DENND4A | DENN/MADD domain containing 4A |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| ECT2 | epithelial cell transforming 2 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 |
| EGR3 | early growth response 3 |
| ELMO2 | engulfment and cell motility 2 |
| EXOC5 | exocyst complex component 5 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM188A | family with sequence similarity 188, member A |
| FH | fumarate hydratase |
| GPR183 | G protein-coupled receptor 183 |
| GPR65 | G protein-coupled receptor 65 |
| GRK6 | G protein-coupled receptor kinase 6 |
| GSE1 | Gse1 coiled-coil protein |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H4J | histone cluster 1, H4j |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IGF2R | insulin-like growth factor 2 receptor |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| KLHL20 | kelch-like family member 20 |
| LAMP2 | lysosomal-associated membrane protein 2 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBTD1 | mbt domain containing 1 |
| MTMR6 | myotubularin related protein 6 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NDRG2 | NDRG family member 2 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NOTCH2 | notch 2 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NRP1 | neuropilin 1 |
| OGFR | opioid growth factor receptor |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PTBP3 | polypyrimidine tract binding protein 3 |
| RAB11A | RAB11A, member RAS oncogene family |
| RAD1 | RAD1 checkpoint DNA exonuclease |
| RAD17 | RAD17 homolog (S. pombe) |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RBL2 | retinoblastoma-like 2 |
| RBM12B | RNA binding motif protein 12B |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RECQL | RecQ helicase-like |
| RECQL4 | RecQ protein-like 4 |
| RECQL5 | RecQ protein-like 5 |
| RNF170 | ring finger protein 170 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPS2 | ribosomal protein S2 |
| RPS9 | ribosomal protein S9 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SETD4 | SET domain containing 4 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMC3 | structural maintenance of chromosomes 3 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPN | sialophorin |
| SSR1 | signal sequence receptor, alpha |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TSPYL2 | TSPY-like 2 |
| TUBA4B | tubulin, alpha 4b |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UBXN2B | UBX domain protein 2B |
| UFL1 | UFM1-specific ligase 1 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WDR91 | WD repeat domain 91 |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF426 | zinc finger protein 426 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ALDOC | aldolase C, fructose-bisphosphate |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCORL1 | BCL6 corepressor-like 1 |
| BRD9 | bromodomain containing 9 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCDC176 | coiled-coil domain containing 176 |
| CD248 | CD248 molecule, endosialin |
| CD38 | CD38 molecule |
| CD69 | CD69 molecule |
| CD82 | CD82 molecule |
| CDC25A | cell division cycle 25A |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP70 | centrosomal protein 70kDa |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CFAP74 | cilia and flagella associated protein 74 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLK3 | CDC-like kinase 3 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CYB561D2 | cytochrome b561 family, member D2 |
| DDA1 | DET1 and DDB1 associated 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| EGR1 | early growth response 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FKBP2 | FK506 binding protein 2, 13kDa |
| GOLGA3 | golgin A3 |
| GPR27 | G protein-coupled receptor 27 |
| GRPR | gastrin-releasing peptide receptor |
| GSR | glutathione reductase |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| IL2RG | interleukin 2 receptor, gamma |
| IRF7 | interferon regulatory factor 7 |
| KRT38 | keratin 38, type I |
| LCT | lactase |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 |
| LRRC42 | leucine rich repeat containing 42 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MED24 | mediator complex subunit 24 |
| MLPH | melanophilin |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPS34 | mitochondrial ribosomal protein S34 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PSKH1 | protein serine kinase H1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB20 | RAB20, member RAS oncogene family |
| RBM15B | RNA binding motif protein 15B |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RNF146 | ring finger protein 146 |
| RRP1 | ribosomal RNA processing 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLN | sarcolipin |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STAC | SH3 and cysteine rich domain |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STC2 | stanniocalcin 2 |
| TAOK1 | TAO kinase 1 |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TCTN2 | tectonic family member 2 |
| TERT | telomerase reverse transcriptase |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TRIM22 | tripartite motif containing 22 |
| TSPAN32 | tetraspanin 32 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| WRN | Werner syndrome, RecQ helicase-like |
| XDH | xanthine dehydrogenase |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF189 | zinc finger protein 189 |
| ZNF197 | zinc finger protein 197 |
| ZNF282 | zinc finger protein 282 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
