| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the zaprinast-6749 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACRV1 | acrosomal vesicle protein 1 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATP10B | ATPase, class V, type 10B |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| AURKA | aurora kinase A |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BNC1 | basonuclin 1 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C3 | complement component 3 |
| CASKIN2 | CASK interacting protein 2 |
| CCDC40 | coiled-coil domain containing 40 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CES1 | carboxylesterase 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHRNB3 | cholinergic receptor, nicotinic, beta 3 (neuronal) |
| CNTFR | ciliary neurotrophic factor receptor |
| CNTN1 | contactin 1 |
| CORO2B | coronin, actin binding protein, 2B |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| DAPK3 | death-associated protein kinase 3 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DRP2 | dystrophin related protein 2 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM134B | family with sequence similarity 134, member B |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GATA3 | GATA binding protein 3 |
| GK3P | glycerol kinase 3 pseudogene |
| GRM8 | glutamate receptor, metabotropic 8 |
| HIRA | histone cell cycle regulator |
| HIST1H3E | histone cluster 1, H3e |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| IL11 | interleukin 11 |
| IL33 | interleukin 33 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KIAA0040 | KIAA0040 |
| KIAA1467 | KIAA1467 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| LAMC2 | laminin, gamma 2 |
| LOXL3 | lysyl oxidase-like 3 |
| LRRC15 | leucine rich repeat containing 15 |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NUP88 | nucleoporin 88kDa |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| PARVA | parvin, alpha |
| PODXL2 | podocalyxin-like 2 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RHOT2 | ras homolog family member T2 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC6A16 | solute carrier family 6, member 16 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOCS6 | suppressor of cytokine signaling 6 |
| SYNJ2 | synaptojanin 2 |
| TBCD | tubulin folding cofactor D |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRIOBP | TRIO and F-actin binding protein |
| UNC119 | unc-119 homolog (C. elegans) |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| WIZ | widely interspaced zinc finger motifs |
| YIPF4 | Yip1 domain family, member 4 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF117 | zinc finger protein 117 |
| ZNF280B | zinc finger protein 280B |
| Symbol | Name |
|---|---|
| ACE | angiotensin I converting enzyme |
| ADAM23 | ADAM metallopeptidase domain 23 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CARTPT | CART prepropeptide |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD68 | CD68 molecule |
| CD72 | CD72 molecule |
| CHM | choroideremia (Rab escort protein 1) |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DDN | dendrin |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DUOX2 | dual oxidase 2 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EPN1 | epsin 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FGL1 | fibrinogen-like 1 |
| FKBP5 | FK506 binding protein 5 |
| FRK | fyn-related Src family tyrosine kinase |
| FRMD8 | FERM domain containing 8 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GRAMD1C | GRAM domain containing 1C |
| GRM4 | glutamate receptor, metabotropic 4 |
| GTF2I | general transcription factor IIi |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3F | histone cluster 1, H3f |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFT140 | intraflagellar transport 140 |
| IL36RN | interleukin 36 receptor antagonist |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITK | IL2-inducible T-cell kinase |
| LMBR1L | limb development membrane protein 1-like |
| LRRK1 | leucine-rich repeat kinase 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| NEUROD1 | neuronal differentiation 1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OCA2 | oculocutaneous albinism II |
| OSBP2 | oxysterol binding protein 2 |
| OSMR | oncostatin M receptor |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAMEF10 | PRAME family member 10 |
| PRSS53 | protease, serine, 53 |
| QSER1 | glutamine and serine rich 1 |
| RAB40A | RAB40A, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAG2 | recombination activating gene 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC26A4 | solute carrier family 26 (anion exchanger), member 4 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPEG | SPEG complex locus |
| SPRYD7 | SPRY domain containing 7 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SYTL2 | synaptotagmin-like 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBC1D22B | TBC1 domain family, member 22B |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSC22D4 | TSC22 domain family, member 4 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF471 | zinc finger protein 471 |
| ZNF480 | zinc finger protein 480 |
| ZNF654 | zinc finger protein 654 |
| ZNF749 | zinc finger protein 749 |
| ZXDB | zinc finger, X-linked, duplicated B |
