zardaverine-4209 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the zardaverine-4209 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALPP alkaline phosphatase, placental
APOB apolipoprotein B
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASCL1 achaete-scute family bHLH transcription factor 1
BCL2A1 BCL2-related protein A1
C11ORF63 chromosome 11 open reading frame 63
C6ORF10 chromosome 6 open reading frame 10
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK13 cyclin-dependent kinase 13
CEMIP cell migration inducing protein, hyaluronan binding
CHAD chondroadherin
CTC1 CTS telomere maintenance complex component 1
CTH cystathionine gamma-lyase
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DCSTAMP dendrocyte expressed seven transmembrane protein
DFNB31 deafness, autosomal recessive 31
DKK3 dickkopf WNT signaling pathway inhibitor 3
DMBT1 deleted in malignant brain tumors 1
DMP1 dentin matrix acidic phosphoprotein 1
DOK4 docking protein 4
DUSP1 dual specificity phosphatase 1
FAM149A family with sequence similarity 149, member A
FCAR Fc fragment of IgA receptor
GK glycerol kinase
GPR63 G protein-coupled receptor 63
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRM2 glutamate receptor, metabotropic 2
GSPT1 G1 to S phase transition 1
HIPK3 homeodomain interacting protein kinase 3
HLA-DMB major histocompatibility complex, class II, DM beta
HOXB3 homeobox B3
HPSE2 heparanase 2 (inactive)
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IAPP islet amyloid polypeptide
ICA1 islet cell autoantigen 1, 69kDa
IL11 interleukin 11
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
INADL InaD-like (Drosophila)
ISG20 interferon stimulated exonuclease gene 20kDa
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF25-AS1 KIF25 antisense RNA 1
KRTAP5-9 keratin associated protein 5-9
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LOX lysyl oxidase
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAP7 microtubule-associated protein 7
MORC1 MORC family CW-type zinc finger 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPAS3 neuronal PAS domain protein 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
OVOL1 ovo-like zinc finger 1
PADI4 peptidyl arginine deiminase, type IV
PDE4B phosphodiesterase 4B, cAMP-specific
PELO pelota homolog (Drosophila)
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLXNC1 plexin C1
POPDC2 popeye domain containing 2
PROSC proline synthetase co-transcribed homolog (bacterial)
PSCA prostate stem cell antigen
PTHLH parathyroid hormone-like hormone
RAB36 RAB36, member RAS oncogene family
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBFA ribosome binding factor A (putative)
RFPL3 ret finger protein-like 3
RIC3 RIC3 acetylcholine receptor chaperone
SATB2 SATB homeobox 2
SCN1B sodium channel, voltage gated, type I beta subunit
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMOX spermine oxidase
SP100 SP100 nuclear antigen
SP110 SP110 nuclear body protein
SP140 SP140 nuclear body protein
SPAG8 sperm associated antigen 8
SPG20 spastic paraplegia 20 (Troyer syndrome)
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STC1 stanniocalcin 1
STRA6 stimulated by retinoic acid 6
TAAR5 trace amine associated receptor 5
TGS1 trimethylguanosine synthase 1
TMEM144 transmembrane protein 144
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UPK1B uroplakin 1B
VTCN1 V-set domain containing T cell activation inhibitor 1
WFDC2 WAP four-disulfide core domain 2
WSB1 WD repeat and SOCS box containing 1
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADTRP androgen-dependent TFPI-regulating protein
AFAP1 actin filament associated protein 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCAS3 breast carcinoma amplified sequence 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC3 baculoviral IAP repeat containing 3
BOLA1 bolA family member 1
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF105 chromosome 1 open reading frame 105
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1RL complement component 1, r subcomponent-like
C3ORF36 chromosome 3 open reading frame 36
C5ORF42 chromosome 5 open reading frame 42
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CFAP69 cilia and flagella associated protein 69
CLDN15 claudin 15
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORO1A coronin, actin binding protein, 1A
CPB1 carboxypeptidase B1 (tissue)
CRYGC crystallin, gamma C
CSRNP3 cysteine-serine-rich nuclear protein 3
DCAF4 DDB1 and CUL4 associated factor 4
FAM184A family with sequence similarity 184, member A
FANCC Fanconi anemia, complementation group C
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FMO4 flavin containing monooxygenase 4
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GBX2 gastrulation brain homeobox 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIF gastric intrinsic factor (vitamin B synthesis)
GMEB1 glucocorticoid modulatory element binding protein 1
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AJ histone cluster 1, H2aj
HIST1H3F histone cluster 1, H3f
HOXA6 homeobox A6
HOXB2 homeobox B2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT140 intraflagellar transport 140
IFT54 intraflagellar transport 54
IL15RA interleukin 15 receptor, alpha
IL17RB interleukin 17 receptor B
IL6 interleukin 6
IPO8 importin 8
KIFC3 kinesin family member C3
KLF3 Kruppel-like factor 3 (basic)
LENEP lens epithelial protein
LMTK1 lemur tail kinase 1
LRRC37A3 leucine rich repeat containing 37, member A3
MMP2 matrix metallopeptidase 2
MRPL41 mitochondrial ribosomal protein L41
MYOZ3 myozenin 3
NDRG4 NDRG family member 4
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLGN1 neuroligin 1
NXPH4 neurexophilin 4
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
ORAI3 ORAI calcium release-activated calcium modulator 3
PAIP2B poly(A) binding protein interacting protein 2B
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMCH pro-melanin-concentrating hormone
POM121 POM121 transmembrane nucleoporin
PRO2964 uncharacterized protein PRO2964
PTPRH protein tyrosine phosphatase, receptor type, H
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF126P1 ring finger protein 126 pseudogene 1
RUNDC3B RUN domain containing 3B
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
STARD5 StAR-related lipid transfer (START) domain containing 5
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
THBS3 thrombospondin 3
TLR2 toll-like receptor 2
TMEM121 transmembrane protein 121
TMEM132A transmembrane protein 132A
TRAPPC6A trafficking protein particle complex 6A
VGLL3 vestigial-like family member 3
XYLT2 xylosyltransferase II
ZNF225 zinc finger protein 225
ZNF34 zinc finger protein 34
ZNF391 zinc finger protein 391
ZNF480 zinc finger protein 480
ZNF778 zinc finger protein 778