| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the zardaverine-4793 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| APOE | apolipoprotein E |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ATM | ATM serine/threonine kinase |
| B9D1 | B9 protein domain 1 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CAPRIN1 | cell cycle associated protein 1 |
| CBR4 | carbonyl reductase 4 |
| CCNG2 | cyclin G2 |
| CD72 | CD72 molecule |
| CDC14A | cell division cycle 14A |
| COMMD4 | COMM domain containing 4 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DCT | dopachrome tautomerase |
| EFS | embryonal Fyn-associated substrate |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| EPHA1 | EPH receptor A1 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| EXOC5 | exocyst complex component 5 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAS | Fas cell surface death receptor |
| FGF13 | fibroblast growth factor 13 |
| FH | fumarate hydratase |
| FRMD1 | FERM domain containing 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GRB10 | growth factor receptor-bound protein 10 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXA6 | homeobox A6 |
| IPO8 | importin 8 |
| ITGA10 | integrin, alpha 10 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KLK13 | kallikrein-related peptidase 13 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MCL1 | myeloid cell leukemia 1 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial |
| MSH6 | mutS homolog 6 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PAPOLA | poly(A) polymerase alpha |
| PARD6B | par-6 family cell polarity regulator beta |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB11B | RAB11B, member RAS oncogene family |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 |
| RBBP9 | retinoblastoma binding protein 9 |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RGS14 | regulator of G-protein signaling 14 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SMAD5 | SMAD family member 5 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| SQLE | squalene epoxidase |
| SRPK2 | SRSF protein kinase 2 |
| SSBP2 | single-stranded DNA binding protein 2 |
| STAB2 | stabilin 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPMT | thiopurine S-methyltransferase |
| TROVE2 | TROVE domain family, member 2 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| VAMP5 | vesicle-associated membrane protein 5 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZNF573 | zinc finger protein 573 |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADCY7 | adenylate cyclase 7 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| AXIN1 | axin 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| BTD | biotinidase |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN15 | calpain 15 |
| CCDC186 | coiled-coil domain containing 186 |
| CCNL2 | cyclin L2 |
| CDK3 | cyclin-dependent kinase 3 |
| CIC | capicua transcriptional repressor |
| CNN2 | calponin 2 |
| CUEDC1 | CUE domain containing 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DYSF | dysferlin |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM110B | family with sequence similarity 110, member B |
| FAM155B | family with sequence similarity 155, member B |
| FAM63A | family with sequence similarity 63, member A |
| FBXO31 | F-box protein 31 |
| FHOD1 | formin homology 2 domain containing 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0894 | KIAA0894 protein |
| KLHL26 | kelch-like family member 26 |
| LHX1 | LIM homeobox 1 |
| LIF | leukemia inhibitory factor |
| LIN7B | lin-7 homolog B (C. elegans) |
| MED24 | mediator complex subunit 24 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MUC3B | mucin 3B, cell surface associated |
| NDRG1 | N-myc downstream regulated 1 |
| NEUROD4 | neuronal differentiation 4 |
| NKX3-2 | NK3 homeobox 2 |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMF1 | polyamine-modulated factor 1 |
| PODXL2 | podocalyxin-like 2 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SDC3 | syndecan 3 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SH2D4A | SH2 domain containing 4A |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TBC1D10B | TBC1 domain family, member 10B |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TMEM121 | transmembrane protein 121 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRIM25 | tripartite motif containing 25 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TUBA3C | tubulin, alpha 3c |
| TXLNA | taxilin alpha |
| UNC119 | unc-119 homolog (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VEGFB | vascular endothelial growth factor B |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR18 | WD repeat domain 18 |
| WDR19 | WD repeat domain 19 |
| XYLT2 | xylosyltransferase II |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF324 | zinc finger protein 324 |
| ZNF446 | zinc finger protein 446 |
| ZNF747 | zinc finger protein 747 |