zellweger syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A peroxisomal disease that is characterized by the reduction or absence of functional peroxisomes in the cells of an individual that has_material_basis_in autosomal recessive inheritance of a mutation in the peroxisome biogenesis factor (PEX) genes. (Human Disease Ontology, DOID_905)
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Genes

95 genes co-occuring with the disease zellweger syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GNPAT glyceronephosphate O-acyltransferase 2.71105
PEX1 peroxisomal biogenesis factor 1 2.70986
PEX2 peroxisomal biogenesis factor 2 2.55559
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 2.40621
PEX6 peroxisomal biogenesis factor 6 2.40466
PEX12 peroxisomal biogenesis factor 12 2.36957
PEX16 peroxisomal biogenesis factor 16 2.34323
PEX13 peroxisomal biogenesis factor 13 2.24683
PEX26 peroxisomal biogenesis factor 26 2.22392
PEX3 peroxisomal biogenesis factor 3 2.18447
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.91827
PEX14 peroxisomal biogenesis factor 14 1.86186
CAT catalase 1.84954
PEX10 peroxisomal biogenesis factor 10 1.84318
PIPOX pipecolic acid oxidase 1.83727
ACAA1 acetyl-CoA acyltransferase 1 1.83092
ACOX3 acyl-CoA oxidase 3, pristanoyl 1.57913
PEX5 peroxisomal biogenesis factor 5 1.572
SCP2 sterol carrier protein 2 1.54495
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.53568
KLHL13 kelch-like family member 13 1.53172
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.46891
PHYH phytanoyl-CoA 2-hydroxylase 1.45177
TYSND1 trypsin domain containing 1 1.41271
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.37905
PMVK phosphomevalonate kinase 1.36248
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.29003
CCDC62 coiled-coil domain containing 62 1.25428
FRRS1L ferric-chelate reductase 1-like 1.22518
PGAM5 phosphoglycerate mutase family member 5 1.17378
PEX19 peroxisomal biogenesis factor 19 1.16221
MVK mevalonate kinase 1.15368
ACOX2 acyl-CoA oxidase 2, branched chain 1.1473
ACAA2 acetyl-CoA acyltransferase 2 1.11814
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 1.11393
SH3BP4 SH3-domain binding protein 4 1.10175
DAO D-amino-acid oxidase 1.1009
SRPK3 SRSF protein kinase 3 1.06144
HACL1 2-hydroxyacyl-CoA lyase 1 1.03956
AGXT alanine-glyoxylate aminotransferase 0.989379
AGPS alkylglycerone phosphate synthase 0.938704
SSR4 signal sequence receptor, delta 0.910199
PLXNB3 plexin B3 0.882292
AMACR alpha-methylacyl-CoA racemase 0.842163
IDI1 isopentenyl-diphosphate delta isomerase 1 0.821257
DNAH8 dynein, axonemal, heavy chain 8 0.80977
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 0.808539
DDO D-aspartate oxidase 0.785165
MID1 midline 1 0.778204
UGT8 UDP glycosyltransferase 8 0.702732
BCAP31 B-cell receptor-associated protein 31 0.691896
FKTN fukutin 0.691094
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.674315
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.66914
AKR1D1 aldo-keto reductase family 1, member D1 0.637889
CERK ceramide kinase 0.606543
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.580439
PDZD4 PDZ domain containing 4 0.578883
MVD mevalonate (diphospho) decarboxylase 0.574994
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.563723
TPR translocated promoter region, nuclear basket protein 0.563335
SREBF2 sterol regulatory element binding transcription factor 2 0.546644
MFF mitochondrial fission factor 0.545093
TMEM245 transmembrane protein 245 0.508808
TPH2 tryptophan hydroxylase 2 0.476772
DCLK1 doublecortin-like kinase 1 0.468063
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.453339
ACAT1 acetyl-CoA acetyltransferase 1 0.429266
MYO5A myosin VA (heavy chain 12, myoxin) 0.427765
SUOX sulfite oxidase 0.412779
TALDO1 transaldolase 1 0.409787
ASL argininosuccinate lyase 0.403438
ACADVL acyl-CoA dehydrogenase, very long chain 0.398216
NES nestin 0.397471
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.397098
DCX doublecortin 0.372958
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.361133
EN1 engrailed homeobox 1 0.358183
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.356709
FFAR1 free fatty acid receptor 1 0.310652
MARCKS myristoylated alanine-rich protein kinase C substrate 0.299092
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.284371
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.283297
TSKU tsukushi, small leucine rich proteoglycan 0.271886
SPAST spastin 0.263722
ASPA aspartoacylase 0.24996
GSS glutathione synthetase 0.241895
GALNS galactosamine (N-acetyl)-6-sulfatase 0.221108
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.204263
UGCG UDP-glucose ceramide glucosyltransferase 0.20229
FDPS farnesyl diphosphate synthase 0.200982
SRI sorcin 0.199356
RPS19 ribosomal protein S19 0.171286
PER3 period circadian clock 3 0.161331
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.158778