zidovudine-3211 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the zidovudine-3211 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADAM29 ADAM metallopeptidase domain 29
AGFG2 ArfGAP with FG repeats 2
APAF1 apoptotic peptidase activating factor 1
ARID1A AT rich interactive domain 1A (SWI-like)
ARL3 ADP-ribosylation factor-like 3
ATP11A ATPase, class VI, type 11A
BCAM basal cell adhesion molecule (Lutheran blood group)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C3 complement component 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC81 coiled-coil domain containing 81
CCL27 chemokine (C-C motif) ligand 27
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK13 cyclin-dependent kinase 13
CELF3 CUGBP, Elav-like family member 3
CHAT choline O-acetyltransferase
CHST10 carbohydrate sulfotransferase 10
CIB2 calcium and integrin binding family member 2
COL14A1 collagen, type XIV, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL6A1 collagen, type VI, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CST4 cystatin S
EGR1 early growth response 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERCC2 excision repair cross-complementation group 2
FAM65B family with sequence similarity 65, member B
FCAR Fc fragment of IgA receptor
FCMR Fc fragment of IgM receptor
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOXI1 forkhead box I1
FRMD1 FERM domain containing 1
FRY furry homolog (Drosophila)
GFI1 growth factor independent 1 transcription repressor
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR20 G protein-coupled receptor 20
GRIK5 glutamate receptor, ionotropic, kainate 5
GSAP gamma-secretase activating protein
HCRP1 hepatocellular carcinoma-related HCRP1
HCRTR2 hypocretin (orexin) receptor 2
HFE hemochromatosis
HHAT hedgehog acyltransferase
HIST1H3E histone cluster 1, H3e
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPS1 Hermansky-Pudlak syndrome 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IAPP islet amyloid polypeptide
IBSP integrin-binding sialoprotein
IHH indian hedgehog
IL22 interleukin 22
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LINC00260 long intergenic non-protein coding RNA 260
MAP2K7 mitogen-activated protein kinase kinase 7
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MOBP myelin-associated oligodendrocyte basic protein
MRPL41 mitochondrial ribosomal protein L41
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NOVA2 neuro-oncological ventral antigen 2
OCLM oculomedin
OMG oligodendrocyte myelin glycoprotein
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PAX4 paired box 4
PCBP3 poly(rC) binding protein 3
PDE3B phosphodiesterase 3B, cGMP-inhibited
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLXDC1 plexin domain containing 1
PML promyelocytic leukemia
PPP5C protein phosphatase 5, catalytic subunit
PROL1 proline rich, lacrimal 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
REEP2 receptor accessory protein 2
RFXAP regulatory factor X-associated protein
RTEL1 regulator of telomere elongation helicase 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT5 sirtuin 5
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SRCAP Snf2-related CREBBP activator protein
STXBP5L syntaxin binding protein 5-like
TCP11L1 t-complex 11, testis-specific-like 1
THAP3 THAP domain containing, apoptosis associated protein 3
THRB thyroid hormone receptor, beta
TLE4 transducin-like enhancer of split 4
TMEM63A transmembrane protein 63A
TNNT2 troponin T type 2 (cardiac)
TNS1 tensin 1
TSKS testis-specific serine kinase substrate
VASH1 vasohibin 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XDH xanthine dehydrogenase
XIST X inactive specific transcript (non-protein coding)
ZNF280A zinc finger protein 280A

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACBD4 acyl-CoA binding domain containing 4
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADM adrenomedullin
BCL9 B-cell CLL/lymphoma 9
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF95 chromosome 10 open reading frame 95
C11ORF16 chromosome 11 open reading frame 16
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
C21ORF91 chromosome 21 open reading frame 91
C8ORF60 chromosome 8 open reading frame 60
CALCOCO1 calcium binding and coiled-coil domain 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX4 chromobox homolog 4
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD83 CD83 molecule
CENPO centromere protein O
CES1 carboxylesterase 1
CFAP69 cilia and flagella associated protein 69
CLCN6 chloride channel, voltage-sensitive 6
CNGB3 cyclic nucleotide gated channel beta 3
CNN2 calponin 2
CRLF1 cytokine receptor-like factor 1
CRY2 cryptochrome circadian clock 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DOC2A double C2-like domains, alpha
DOCK1 dedicator of cytokinesis 1
DUSP13 dual specificity phosphatase 13
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELOVL4 ELOVL fatty acid elongase 4
ENO2 enolase 2 (gamma, neuronal)
F8 coagulation factor VIII, procoagulant component
FAM53C family with sequence similarity 53, member C
FBRS fibrosin
FLJ21369 uncharacterized protein FLJ21369
FMOD fibromodulin
FOSL1 FOS-like antigen 1
FURIN furin (paired basic amino acid cleaving enzyme)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR1 G protein-coupled receptor 1
HAMP hepcidin antimicrobial peptide
HIST1H2AL histone cluster 1, H2al
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IDI2-AS1 IDI2 antisense RNA 1
IRAK4 interleukin-1 receptor-associated kinase 4
IRF7 interferon regulatory factor 7
ITGA10 integrin, alpha 10
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LDHB lactate dehydrogenase B
LHX6 LIM homeobox 6
LMO2 LIM domain only 2 (rhombotin-like 1)
LY6D lymphocyte antigen 6 complex, locus D
LYZ lysozyme
MCRS1 microspherule protein 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MUC3B mucin 3B, cell surface associated
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDE12 phosphodiesterase 12
PGR progesterone receptor
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLTP phospholipid transfer protein
PODXL2 podocalyxin-like 2
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PTTG3P pituitary tumor-transforming 3, pseudogene
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RPAP1 RNA polymerase II associated protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERGEF secretion regulating guanine nucleotide exchange factor
SLC22A14 solute carrier family 22, member 14
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
TCTN1 tectonic family member 1
TICAM1 toll-like receptor adaptor molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNRC6B trinucleotide repeat containing 6B
TNS2 tensin 2
TTC33 tetratricopeptide repeat domain 33
TWF2 twinfilin actin binding protein 2
ULBP2 UL16 binding protein 2
UNC93B1 unc-93 homolog B1 (C. elegans)
URM1 ubiquitin related modifier 1
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC18 zinc finger, DHHC-type containing 18
ZIC3 Zic family member 3
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF606 zinc finger protein 606
ZNF696 zinc finger protein 696