zimeldine-1930 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the zimeldine-1930 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADARB1 adenosine deaminase, RNA-specific, B1
AK1 adenylate kinase 1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APP amyloid beta (A4) precursor protein
AQP6 aquaporin 6, kidney specific
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATXN7L3B ataxin 7-like 3B
AXIN1 axin 1
BOLA1 bolA family member 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCDC71 coiled-coil domain containing 71
CCNG2 cyclin G2
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK12 cyclin-dependent kinase 12
CDK18 cyclin-dependent kinase 18
CENPO centromere protein O
CEP41 centrosomal protein 41kDa
CER1 cerberus 1, DAN family BMP antagonist
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAXX death-domain associated protein
ECE2 endothelin converting enzyme 2
EDA ectodysplasin A
ELL2 elongation factor, RNA polymerase II, 2
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
GFER growth factor, augmenter of liver regeneration
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR137 G protein-coupled receptor 137
HMGN5 high mobility group nucleosome binding domain 5
IFFO1 intermediate filament family orphan 1
INSL4 insulin-like 4 (placenta)
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIF5A kinesin family member 5A
KLF6 Kruppel-like factor 6
KRT32 keratin 32, type I
LAMA4 laminin, alpha 4
LAT2 linker for activation of T cells family, member 2
MAGEF1 melanoma antigen family F1
MAPK7 mitogen-activated protein kinase 7
MFN2 mitofusin 2
MFSD11 major facilitator superfamily domain containing 11
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPI mannose phosphate isomerase
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MZF1 myeloid zinc finger 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NELL2 NEL-like 2 (chicken)
NEUROD4 neuronal differentiation 4
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE4DIP phosphodiesterase 4D interacting protein
PGC progastricsin (pepsinogen C)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKNOX2 PBX/knotted 1 homeobox 2
POMT2 protein-O-mannosyltransferase 2
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRSS8 protease, serine, 8
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTN pleiotrophin
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB3A RAB3A, member RAS oncogene family
RANBP9 RAN binding protein 9
REEP1 receptor accessory protein 1
RNF141 ring finger protein 141
RPL10L ribosomal protein L10-like
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SH2B2 SH2B adaptor protein 2
SH3BP2 SH3-domain binding protein 2
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SMAD5 SMAD family member 5
SPANXC SPANX family, member C
SPPL2B signal peptide peptidase like 2B
SSBP3 single stranded DNA binding protein 3
STRA6 stimulated by retinoic acid 6
TBX2 T-box 2
TCF20 transcription factor 20 (AR1)
TMSB15A thymosin beta 15a
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNS2 tensin 2
TRIM3 tripartite motif containing 3
TYMP thymidine phosphorylase
VIPR1 vasoactive intestinal peptide receptor 1
VIPR2 vasoactive intestinal peptide receptor 2
WRN Werner syndrome, RecQ helicase-like
ZER1 zyg-11 related, cell cycle regulator
ZFR zinc finger RNA binding protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF24 zinc finger protein 24
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACSF2 acyl-CoA synthetase family member 2
AHNAK2 AHNAK nucleoprotein 2
ANXA2P3 annexin A2 pseudogene 3
ARHGAP5 Rho GTPase activating protein 5
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMT1 acidic residue methyltransferase 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C12ORF29 chromosome 12 open reading frame 29
CASP7 caspase 7, apoptosis-related cysteine peptidase
CEP85 centrosomal protein 85kDa
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLK2 CDC-like kinase 2
CNOT7 CCR4-NOT transcription complex, subunit 7
COPZ1 coatomer protein complex, subunit zeta 1
CPOX coproporphyrinogen oxidase
CTDNEP1 CTD nuclear envelope phosphatase 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXCL6 chemokine (C-X-C motif) ligand 6
DAAM1 dishevelled associated activator of morphogenesis 1
DDA1 DET1 and DDB1 associated 1
DENND1B DENN/MADD domain containing 1B
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DPYD dihydropyrimidine dehydrogenase
ECT2 epithelial cell transforming 2
EMC9 ER membrane protein complex subunit 9
ERBB2IP erbb2 interacting protein
FAF1 Fas (TNFRSF6) associated factor 1
FAM188A family with sequence similarity 188, member A
FANCC Fanconi anemia, complementation group C
FBXL14 F-box and leucine-rich repeat protein 14
FBXO5 F-box protein 5
FGFBP1 fibroblast growth factor binding protein 1
FUBP3 far upstream element (FUSE) binding protein 3
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HLX H2.0-like homeobox
JADE3 jade family PHD finger 3
KCTD3 potassium channel tetramerization domain containing 3
KLC2 kinesin light chain 2
KLF2 Kruppel-like factor 2
LACTB2 lactamase, beta 2
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMNB1 lamin B1
LRIF1 ligand dependent nuclear receptor interacting factor 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK3 mitogen-activated protein kinase 3
MED17 mediator complex subunit 17
MINPP1 multiple inositol-polyphosphate phosphatase 1
MORC3 MORC family CW-type zinc finger 3
MRPL19 mitochondrial ribosomal protein L19
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NOL6 nucleolar protein 6 (RNA-associated)
NUCLEOLIN nucleolin multifunctional protein
ORC2 origin recognition complex, subunit 2
PAK1IP1 PAK1 interacting protein 1
PCNXL4 pecanex-like 4 (Drosophila)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRCC papillary renal cell carcinoma (translocation-associated)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
REPIN1 replication initiator 1
RHOB ras homolog family member B
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RRP1 ribosomal RNA processing 1
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SAR1B secretion associated, Ras related GTPase 1B
SDCCAG3 serologically defined colon cancer antigen 3
SDHAF3 succinate dehydrogenase complex assembly factor 3
SHCBP1 SHC SH2-domain binding protein 1
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLMO2 slowmo homolog 2 (Drosophila)
SNAI2 snail family zinc finger 2
SPAG1 sperm associated antigen 1
SPRY2 sprouty homolog 2 (Drosophila)
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STK26 serine/threonine protein kinase 26
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
TACC3 transforming, acidic coiled-coil containing protein 3
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TMEM185B transmembrane protein 185B
TMEM251 transmembrane protein 251
TOP2B topoisomerase (DNA) II beta 180kDa
TRIM8 tripartite motif containing 8
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTI1 TELO2 interacting protein 1
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBA2 ubiquitin-like modifier activating enzyme 2
UFM1 ubiquitin-fold modifier 1
ZNF217 zinc finger protein 217
ZNF232 zinc finger protein 232
ZNF239 zinc finger protein 239
ZNF652 zinc finger protein 652