| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the zimeldine-1930 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AK1 | adenylate kinase 1 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APP | amyloid beta (A4) precursor protein |
| AQP6 | aquaporin 6, kidney specific |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATXN7L3B | ataxin 7-like 3B |
| AXIN1 | axin 1 |
| BOLA1 | bolA family member 1 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CCDC71 | coiled-coil domain containing 71 |
| CCNG2 | cyclin G2 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK12 | cyclin-dependent kinase 12 |
| CDK18 | cyclin-dependent kinase 18 |
| CENPO | centromere protein O |
| CEP41 | centrosomal protein 41kDa |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAXX | death-domain associated protein |
| ECE2 | endothelin converting enzyme 2 |
| EDA | ectodysplasin A |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| GFER | growth factor, augmenter of liver regeneration |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPR137 | G protein-coupled receptor 137 |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| IFFO1 | intermediate filament family orphan 1 |
| INSL4 | insulin-like 4 (placenta) |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIF5A | kinesin family member 5A |
| KLF6 | Kruppel-like factor 6 |
| KRT32 | keratin 32, type I |
| LAMA4 | laminin, alpha 4 |
| LAT2 | linker for activation of T cells family, member 2 |
| MAGEF1 | melanoma antigen family F1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MFN2 | mitofusin 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MPI | mannose phosphate isomerase |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MZF1 | myeloid zinc finger 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NELL2 | NEL-like 2 (chicken) |
| NEUROD4 | neuronal differentiation 4 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PGC | progastricsin (pepsinogen C) |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRSS8 | protease, serine, 8 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTN | pleiotrophin |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAB3A | RAB3A, member RAS oncogene family |
| RANBP9 | RAN binding protein 9 |
| REEP1 | receptor accessory protein 1 |
| RNF141 | ring finger protein 141 |
| RPL10L | ribosomal protein L10-like |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SH2B2 | SH2B adaptor protein 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 |
| SMAD5 | SMAD family member 5 |
| SPANXC | SPANX family, member C |
| SPPL2B | signal peptide peptidase like 2B |
| SSBP3 | single stranded DNA binding protein 3 |
| STRA6 | stimulated by retinoic acid 6 |
| TBX2 | T-box 2 |
| TCF20 | transcription factor 20 (AR1) |
| TMSB15A | thymosin beta 15a |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNS2 | tensin 2 |
| TRIM3 | tripartite motif containing 3 |
| TYMP | thymidine phosphorylase |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WRN | Werner syndrome, RecQ helicase-like |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFR | zinc finger RNA binding protein |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF24 | zinc finger protein 24 |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARMT1 | acidic residue methyltransferase 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C12ORF29 | chromosome 12 open reading frame 29 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CEP85 | centrosomal protein 85kDa |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CLK2 | CDC-like kinase 2 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 |
| COPZ1 | coatomer protein complex, subunit zeta 1 |
| CPOX | coproporphyrinogen oxidase |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDA1 | DET1 and DDB1 associated 1 |
| DENND1B | DENN/MADD domain containing 1B |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DPYD | dihydropyrimidine dehydrogenase |
| ECT2 | epithelial cell transforming 2 |
| EMC9 | ER membrane protein complex subunit 9 |
| ERBB2IP | erbb2 interacting protein |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FAM188A | family with sequence similarity 188, member A |
| FANCC | Fanconi anemia, complementation group C |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FBXO5 | F-box protein 5 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HLX | H2.0-like homeobox |
| JADE3 | jade family PHD finger 3 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KLC2 | kinesin light chain 2 |
| KLF2 | Kruppel-like factor 2 |
| LACTB2 | lactamase, beta 2 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LMNB1 | lamin B1 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MED17 | mediator complex subunit 17 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NUCLEOLIN | nucleolin multifunctional protein |
| ORC2 | origin recognition complex, subunit 2 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| REPIN1 | replication initiator 1 |
| RHOB | ras homolog family member B |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RRP1 | ribosomal RNA processing 1 |
| SACM1L | SAC1 suppressor of actin mutations 1-like (yeast) |
| SAR1B | secretion associated, Ras related GTPase 1B |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SNAI2 | snail family zinc finger 2 |
| SPAG1 | sperm associated antigen 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
| STK26 | serine/threonine protein kinase 26 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TMEM185B | transmembrane protein 185B |
| TMEM251 | transmembrane protein 251 |
| TOP2B | topoisomerase (DNA) II beta 180kDa |
| TRIM8 | tripartite motif containing 8 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TTI1 | TELO2 interacting protein 1 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBA2 | ubiquitin-like modifier activating enzyme 2 |
| UFM1 | ubiquitin-fold modifier 1 |
| ZNF217 | zinc finger protein 217 |
| ZNF232 | zinc finger protein 232 |
| ZNF239 | zinc finger protein 239 |
| ZNF652 | zinc finger protein 652 |