| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the zimeldine-4609 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABI2 | abl-interactor 2 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALOX5 | arachidonate 5-lipoxygenase |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| AURKC | aurora kinase C |
| BPY2 | basic charge, Y-linked, 2 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CCDC181 | coiled-coil domain containing 181 |
| CD22 | CD22 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DLX5 | distal-less homeobox 5 |
| DOCK9 | dedicator of cytokinesis 9 |
| DRP2 | dystrophin related protein 2 |
| EHD2 | EH-domain containing 2 |
| EN2 | engrailed homeobox 2 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPHA3 | EPH receptor A3 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FABP1 | fatty acid binding protein 1, liver |
| FGFR2 | fibroblast growth factor receptor 2 |
| FRMD8 | FERM domain containing 8 |
| GLRA3 | glycine receptor, alpha 3 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HRG | histidine-rich glycoprotein |
| HSF1 | heat shock transcription factor 1 |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IRS4 | insulin receptor substrate 4 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLHL22 | kelch-like family member 22 |
| KLHL35 | kelch-like family member 35 |
| KSR1 | kinase suppressor of ras 1 |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LCT | lactase |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MTMR7 | myotubularin related protein 7 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MUC4 | mucin 4, cell surface associated |
| MYBPC2 | myosin binding protein C, fast type |
| MYEF2 | myelin expression factor 2 |
| MYO7A | myosin VIIA |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NF2 | neurofibromin 2 (merlin) |
| NRG1 | neuregulin 1 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PACRG | PARK2 co-regulated |
| PADI4 | peptidyl arginine deiminase, type IV |
| PARVA | parvin, alpha |
| PAX2 | paired box 2 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDH11Y | protocadherin 11 Y-linked |
| PCDHB3 | protocadherin beta 3 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PIP | prolactin-induced protein |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNC1 | plexin C1 |
| POM121 | POM121 transmembrane nucleoporin |
| PRF1 | perforin 1 (pore forming protein) |
| PRO2964 | uncharacterized protein PRO2964 |
| PTGDR | prostaglandin D2 receptor (DP) |
| RARB | retinoic acid receptor, beta |
| RASA3 | RAS p21 protein activator 3 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNX1 | runt-related transcription factor 1 |
| SEC24D | SEC24 family member D |
| SLIT3 | slit homolog 3 (Drosophila) |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOX10 | SRY (sex determining region Y)-box 10 |
| TAAR5 | trace amine associated receptor 5 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TMEM140 | transmembrane protein 140 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TNS1 | tensin 1 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPC7 | transient receptor potential cation channel, subfamily C, member 7 |
| TSSK2 | testis-specific serine kinase 2 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ADCY6 | adenylate cyclase 6 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| AXIN1 | axin 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BEX4 | brain expressed, X-linked 4 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CBR4 | carbonyl reductase 4 |
| CDK6 | cyclin-dependent kinase 6 |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CISH | cytokine inducible SH2-containing protein |
| CLASRP | CLK4-associating serine/arginine rich protein |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLIC3 | chloride intracellular channel 3 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNM3 | dynamin 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ETNK2 | ethanolamine kinase 2 |
| FBRS | fibrosin |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| H1F0 | H1 histone family, member 0 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AL | histone cluster 1, H2al |
| IFT140 | intraflagellar transport 140 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| JAM3 | junctional adhesion molecule 3 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KRT75 | keratin 75, type II |
| KRT8P12 | keratin 8 pseudogene 12 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MT1M | metallothionein 1M |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MX1 | MX dynamin-like GTPase 1 |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OSMR | oncostatin M receptor |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PALMD | palmdelphin |
| PDE12 | phosphodiesterase 12 |
| PER3 | period circadian clock 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLCD1 | phospholipase C, delta 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RRAGB | Ras-related GTP binding B |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNX16 | sorting nexin 16 |
| SSBP3 | single stranded DNA binding protein 3 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STK16 | serine/threonine kinase 16 |
| SYNGR3 | synaptogyrin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TRIM58 | tripartite motif containing 58 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| WDR25 | WD repeat domain 25 |
| WDR76 | WD repeat domain 76 |
| YY2 | YY2 transcription factor |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF227 | zinc finger protein 227 |
| ZNF324 | zinc finger protein 324 |
| ZNF34 | zinc finger protein 34 |
| ZNF606 | zinc finger protein 606 |