zimeldine-5670 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the zimeldine-5670 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ACSM1 acyl-CoA synthetase medium-chain family member 1
ACTN2 actinin, alpha 2
AQP3 aquaporin 3 (Gill blood group)
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BCAP29 B-cell receptor-associated protein 29
C8A complement component 8, alpha polypeptide
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CARD10 caspase recruitment domain family, member 10
CCDC71 coiled-coil domain containing 71
CD248 CD248 molecule, endosialin
CD80 CD80 molecule
CD8A CD8a molecule
CDA cytidine deaminase
CIITA class II, major histocompatibility complex, transactivator
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC7A C-type lectin domain family 7, member A
CNN3 calponin 3, acidic
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL14A1 collagen, type XIV, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLX4 distal-less homeobox 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK6 dedicator of cytokinesis 6
ECE1 endothelin converting enzyme 1
EGFR epidermal growth factor receptor
EPHB1 EPH receptor B1
F5 coagulation factor V (proaccelerin, labile factor)
FGF18 fibroblast growth factor 18
FHL1 four and a half LIM domains 1
FSHB follicle stimulating hormone, beta polypeptide
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GFI1B growth factor independent 1B transcription repressor
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HOXB9 homeobox B9
HRH1 histamine receptor H1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IDUA iduronidase, alpha-L-
IL11 interleukin 11
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF1C kinesin family member 1C
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRT33A keratin 33A, type I
KRT83 keratin 83, type II
LIN7A lin-7 homolog A (C. elegans)
LPIN1 lipin 1
MDFI MyoD family inhibitor
METTL7A methyltransferase like 7A
MMP13 matrix metallopeptidase 13
MYO3A myosin IIIA
NEK9 NIMA-related kinase 9
NEUROD4 neuronal differentiation 4
NPTX1 neuronal pentraxin I
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRF1 nuclear respiratory factor 1
OLFM1 olfactomedin 1
OPRK1 opioid receptor, kappa 1
PDE4C phosphodiesterase 4C, cAMP-specific
PLAC1 placenta-specific 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PQLC3 PQ loop repeat containing 3
PRDM1 PR domain containing 1, with ZNF domain
PRDM14 PR domain containing 14
RAB30 RAB30, member RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBM12B RNA binding motif protein 12B
RERE arginine-glutamic acid dipeptide (RE) repeats
RREB1 ras responsive element binding protein 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERGEF secretion regulating guanine nucleotide exchange factor
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMAD3 SMAD family member 3
SPHK2 sphingosine kinase 2
SSTR5 somatostatin receptor 5
TBC1D2B TBC1 domain family, member 2B
TEF thyrotrophic embryonic factor
TNC tenascin C
TNP2 transition protein 2 (during histone to protamine replacement)
TRD T cell receptor delta locus
TRIM10 tripartite motif containing 10
TUBA3C tubulin, alpha 3c
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VIPR1 vasoactive intestinal peptide receptor 1
XCR1 chemokine (C motif) receptor 1
ZIM2 zinc finger, imprinted 2
ZNF460 zinc finger protein 460
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
AHDC1 AT hook, DNA binding motif, containing 1
ANKRD36 ankyrin repeat domain 36
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP10D ATPase, class V, type 10D
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL2L2 BCL2-like 2
BMP15 bone morphogenetic protein 15
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF105 chromosome 1 open reading frame 105
CCDC132 coiled-coil domain containing 132
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD82 CD82 molecule
CDKL3 cyclin-dependent kinase-like 3
CGA glycoprotein hormones, alpha polypeptide
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLGN calmegin
CLSPN claspin
CRIP1 cysteine-rich protein 1 (intestinal)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DGKE diacylglycerol kinase, epsilon 64kDa
ERCC4 excision repair cross-complementation group 4
FAM131A family with sequence similarity 131, member A
FAM155A family with sequence similarity 155, member A
FAM186A family with sequence similarity 186, member A
FAM198B family with sequence similarity 198, member B
FCHO1 FCH domain only 1
FKBPL FK506 binding protein like
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAN gigaxonin
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL1 guanine nucleotide binding protein-like 1
GPATCH2L G patch domain containing 2-like
GPR3 G protein-coupled receptor 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSTA4 glutathione S-transferase alpha 4
GTF2I general transcription factor IIi
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BO histone cluster 1, H2bo
HOXD11 homeobox D11
INPP1 inositol polyphosphate-1-phosphatase
IRF6 interferon regulatory factor 6
ITGA10 integrin, alpha 10
KDM8 lysine (K)-specific demethylase 8
KRT13 keratin 13, type I
LAX1 lymphocyte transmembrane adaptor 1
LIME1 Lck interacting transmembrane adaptor 1
LRRC37A3 leucine rich repeat containing 37, member A3
LTBP2 latent transforming growth factor beta binding protein 2
MATK megakaryocyte-associated tyrosine kinase
MDM4 MDM4, p53 regulator
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTHFSD methenyltetrahydrofolate synthetase domain containing
NXPE3 neurexophilin and PC-esterase domain family, member 3
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PRODH proline dehydrogenase (oxidase) 1
RCAN3 RCAN family member 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGRIP1L RPGRIP1-like
RPL13P5 ribosomal protein L13 pseudogene 5
RUNDC3B RUN domain containing 3B
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH3BGR SH3 domain binding glutamate-rich protein
SIK1 salt-inducible kinase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNHG20 small nucleolar RNA host gene 20
SPAG4 sperm associated antigen 4
TBX19 T-box 19
TCTN2 tectonic family member 2
TDRD1 tudor domain containing 1
TDRD12 tudor domain containing 12
TET3 tet methylcytosine dioxygenase 3
TMEM104 transmembrane protein 104
TMEM180 transmembrane protein 180
TMEM19 transmembrane protein 19
TMEM209 transmembrane protein 209
TPST1 tyrosylprotein sulfotransferase 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
VGF VGF nerve growth factor inducible
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR33 WD repeat domain 33
XK X-linked Kx blood group
XYLT2 xylosyltransferase II
ZNF10 zinc finger protein 10
ZNF324 zinc finger protein 324
ZNF365 zinc finger protein 365
ZNF428 zinc finger protein 428
ZNF506 zinc finger protein 506
ZNF74 zinc finger protein 74