zinc ion binding Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with zinc (Zn) ions. (Gene Ontology, GO_0008270)
External Link http://amigo.geneontology.org/amigo/term/GO:0008270
Similar Terms
Downloads & Tools

Genes

339 genes performing the zinc ion binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACER3 alkaline ceramidase 3
ACMSD aminocarboxymuconate semialdehyde decarboxylase
ACOD1 aconitate decarboxylase 1
ACR acrosin
ADA adenosine deaminase
ADA2 adenosine deaminase 2
ADAM30 ADAM metallopeptidase domain 30
ADAM33 ADAM metallopeptidase domain 33
ADAM8 ADAM metallopeptidase domain 8
ADAMDEC1 ADAM-like, decysin 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADH6 alcohol dehydrogenase 6 (class V)
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AIRE autoimmune regulator
ALAD aminolevulinate dehydratase
ALKBH8 alkB, alkylation repair homolog 8 (E. coli)
ALPP alkaline phosphatase, placental
ANPEP alanyl (membrane) aminopeptidase
APIP APAF1 interacting protein
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ATP13A2 ATPase type 13A2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BHMT betaine--homocysteine S-methyltransferase
BHMT2 betaine--homocysteine S-methyltransferase 2
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
BLM Bloom syndrome, RecQ helicase-like
C11ORF54 chromosome 11 open reading frame 54
CA2 carbonic anhydrase II
CA9 carbonic anhydrase IX
CALB1 calbindin 1, 28kDa
CALR calreticulin
CD4 CD4 molecule
CDA cytidine deaminase
CDADC1 cytidine and dCMP deaminase domain containing 1
CDIP1 cell death-inducing p53 target 1
CDO1 cysteine dioxygenase type 1
CHD3 chromodomain helicase DNA binding protein 3
CHMP1A charged multivesicular body protein 1A
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHURC1-FNTB CHURC1-FNTB readthrough
CLIP1 CAP-GLY domain containing linker protein 1
CNRIP1 cannabinoid receptor interacting protein 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CPA2 carboxypeptidase A2 (pancreatic)
CRIP2 cysteine-rich protein 2
CSRP1 cysteine and glycine-rich protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CXXC4 CXXC finger protein 4
CXXC5 CXXC finger protein 5
CYLD cylindromatosis (turban tumor syndrome)
CZIB CXXC motif containing zinc binding protein
D2HGDH D-2-hydroxyglutarate dehydrogenase
DHH desert hedgehog
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DPEP1 dipeptidase 1 (renal)
DPF3 D4, zinc and double PHD fingers, family 3
DPP3 dipeptidyl-peptidase 3
DPYS dihydropyrimidinase
DUSP12 dual specificity phosphatase 12
ECE1 endothelin converting enzyme 1
EEA1 early endosome antigen 1
EGR1 early growth response 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EPRS1 glutamyl-prolyl-tRNA synthetase 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
FBXL19 F-box and leucine-rich repeat protein 19
GALT galactose-1-phosphate uridylyltransferase
GCH1 GTP cyclohydrolase 1
GDA guanine deaminase
GLI2 GLI family zinc finger 2
GLO1 glyoxalase I
GLRA1 glycine receptor, alpha 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GTF2B general transcription factor IIB
HDAC10 histone deacetylase 10
HDAC4 histone deacetylase 4
HHIP hedgehog interacting protein
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
IDE insulin-degrading enzyme
IFIH1 interferon induced with helicase C domain 1
IKZF4 IKAROS family zinc finger 4 (Eos)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
ISCU iron-sulfur cluster assembly enzyme
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KAT6A K(lysine) acetyltransferase 6A
KDM1B lysine (K)-specific demethylase 1B
KDM2A lysine (K)-specific demethylase 2A
KDM2B lysine (K)-specific demethylase 2B
KDM4A lysine (K)-specific demethylase 4A
KDM4C lysine (K)-specific demethylase 4C
KDM5A lysine (K)-specific demethylase 5A
KDM5B lysine (K)-specific demethylase 5B
KDM5C lysine (K)-specific demethylase 5C
KDM7A lysine (K)-specific demethylase 7A
KLF4 Kruppel-like factor 4 (gut)
KMT2A lysine (K)-specific methyltransferase 2A
KMT2B lysine (K)-specific methyltransferase 2B
KNG1 kininogen 1
KPNB1 karyopherin (importin) beta 1
LACTB2 lactamase, beta 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCN1 lipocalin 1
LIMS1 LIM and senescent cell antigen-like domains 1
LITAF lipopolysaccharide-induced TNF factor
LITAFD LITAF domain containing
LNPEP leucyl/cystinyl aminopeptidase
LTA4H leukotriene A4 hydrolase
LVRN laeverin
MBD1 methyl-CpG binding domain protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP23B matrix metallopeptidase 23B
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MORC2 MORC family CW-type zinc finger 2
MSRB1 methionine sulfoxide reductase B1
MSRB2 methionine sulfoxide reductase B2
MSRB3 methionine sulfoxide reductase B3
MT1A metallothionein 1A
MT1B metallothionein 1B
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MT3 metallothionein 3
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYRIP myosin VIIA and Rab interacting protein
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NPEPPS aminopeptidase puromycin sensitive
NQO2 NAD(P)H dehydrogenase, quinone 2
NRG1 neuregulin 1
NSD1 nuclear receptor binding SET domain protein 1
NT5E 5'-nucleotidase, ecto (CD73)
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPPA2 pappalysin 2
PARP1 poly (ADP-ribose) polymerase 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PEX10 peroxisomal biogenesis factor 10
PEX12 peroxisomal biogenesis factor 12
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHEX phosphate regulating endopeptidase homolog, X-linked
PHF14 PHD finger protein 14
PHF2 PHD finger protein 2
PHF5A PHD finger protein 5A
PHF8 PHD finger protein 8
PIAS4 protein inhibitor of activated STAT, 4
PITRM1 pitrilysin metallopeptidase 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLA2G15 phospholipase A2, group XV
PLSCR1 phospholipid scramblase 1
PML promyelocytic leukemia
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PPARG peroxisome proliferator-activated receptor gamma
PRDM2 PR domain containing 2, with ZNF domain
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIMPOL primase and polymerase (DNA-directed)
PRKN parkin RBR E3 ubiquitin protein ligase
PRM2 protamine 2
PTGR2 prostaglandin reductase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
QPCT glutaminyl-peptide cyclotransferase
QPCTL glutaminyl-peptide cyclotransferase-like
RABGGTB Rab geranylgeranyltransferase, beta subunit
RABIF RAB interacting factor
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBAK-RBAKDN RBAK-RBAKDN readthrough
RBSN rabenosyn, RAB effector
RC3H1 ring finger and CCCH-type domains 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RGN regucalcin
RICTOR RPTOR independent companion of MTOR, complex 2
RIGI RNA sensor RIG-I
RNF112 ring finger protein 112
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF2 ring finger protein 2
RNF26 ring finger protein 26
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPH3A rabphilin 3A
RPS27 ribosomal protein S27
RPS29 ribosomal protein S29
RXRA retinoid X receptor, alpha
S100A12 S100 calcium binding protein A12
S100A13 S100 calcium binding protein A13
S100A5 S100 calcium binding protein A5
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SAMHD1 SAM domain and HD domain 1
SAP30L SAP30-like
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEMG1 semenogelin I
SEMG2 semenogelin II
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHH sonic hedgehog
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT2 sirtuin 2
SIRT3 sirtuin 3
SIRT5 sirtuin 5
SIRT6 sirtuin 6
SIVA1 SIVA1, apoptosis-inducing factor
SKI SKI proto-oncogene
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLFN13 schlafen family member 13
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SMAD3 SMAD family member 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPC small nuclear ribonucleoprotein polypeptide C
SOD1 superoxide dismutase 1, soluble
SORD sorbitol dehydrogenase
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TARS1 threonyl-tRNA synthetase 1
TES testin LIM domain protein
TET1 tet methylcytosine dioxygenase 1
TET2 tet methylcytosine dioxygenase 2
TET3 tet methylcytosine dioxygenase 3
THAP1 THAP domain containing, apoptosis associated protein 1
THAP11 THAP domain containing 11
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TK1 thymidine kinase 1, soluble
TMEM163 transmembrane protein 163
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNP2 transition protein 2 (during histone to protamine replacement)
TP53 tumor protein p53
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM2 tripartite motif containing 2
TRIM24 tripartite motif containing 24
TRIM28 tripartite motif containing 28
TRIM54 tripartite motif containing 54
TRIM8 tripartite motif containing 8
UBA5 ubiquitin-like modifier activating enzyme 5
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UPB1 ureidopropionase, beta
USP21 ubiquitin specific peptidase 21
USP33 ubiquitin specific peptidase 33
WDFY1 WD repeat and FYVE domain containing 1
WT1 Wilms tumor 1
ZACN zinc activated ligand-gated ion channel
ZBTB32 zinc finger and BTB domain containing 32
ZCCHC4 zinc finger, CCHC domain containing 4
ZDHHC15 zinc finger, DHHC-type containing 15
ZDHHC20 zinc finger, DHHC-type containing 20
ZFP37 ZFP37 zinc finger protein
ZFPL1 zinc finger protein-like 1
ZFPM2 zinc finger protein, FOG family member 2
ZFYVE1 zinc finger, FYVE domain containing 1
ZIM2 zinc finger, imprinted 2
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMYM2 zinc finger, MYM-type 2
ZMYND11 zinc finger, MYND-type containing 11
ZMYND8 zinc finger, MYND-type containing 8
ZNF117 zinc finger protein 117
ZNF184 zinc finger protein 184
ZNF185 zinc finger protein 185 (LIM domain)
ZNF195 zinc finger protein 195
ZNF2 zinc finger protein 2
ZNF205 zinc finger protein 205
ZNF208 zinc finger protein 208
ZNF212 zinc finger protein 212
ZNF214 zinc finger protein 214
ZNF282 zinc finger protein 282
ZNF3 zinc finger protein 3
ZNF331 zinc finger protein 331
ZNF593 zinc finger protein 593
ZNF675 zinc finger protein 675
ZNF711 zinc finger protein 711
ZNF75D zinc finger protein 75D
ZNF8 zinc finger protein 8
ZNF84 zinc finger protein 84
ZNF90 zinc finger protein 90
ZNF91 zinc finger protein 91
ZNF92 zinc finger protein 92
ZNF93 zinc finger protein 93