| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the zomepirac-3454 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AMT | aminomethyltransferase |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| APOM | apolipoprotein M |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CARF | calcium responsive transcription factor |
| CD83 | CD83 molecule |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK19 | cyclin-dependent kinase 19 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| COL5A1 | collagen, type V, alpha 1 |
| COMT | catechol-O-methyltransferase |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNPEP | aspartyl aminopeptidase |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EFNA3 | ephrin-A3 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| EPHB2 | EPH receptor B2 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FSCN1 | fascin actin-bundling protein 1 |
| FST | follistatin |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLRX3 | glutaredoxin 3 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTM1 | glutathione S-transferase mu 1 |
| GUK1 | guanylate kinase 1 |
| GYG2 | glycogenin 2 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3I | histone cluster 1, H3i |
| HIST1H4F | histone cluster 1, H4f |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| ICAM1 | intercellular adhesion molecule 1 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KLHL20 | kelch-like family member 20 |
| KRT17 | keratin 17, type I |
| LHX6 | LIM homeobox 6 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MCOLN1 | mucolipin 1 |
| MEFV | Mediterranean fever |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MZT2B | mitotic spindle organizing protein 2B |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NMT1 | N-myristoyltransferase 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RECQL5 | RecQ protein-like 5 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RGS10 | regulator of G-protein signaling 10 |
| SEC24D | SEC24 family member D |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SH2B1 | SH2B adaptor protein 1 |
| SH2D3A | SH2 domain containing 3A |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SMIM14 | small integral membrane protein 14 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SSTR5 | somatostatin receptor 5 |
| STX7 | syntaxin 7 |
| SYT12 | synaptotagmin XII |
| TAPBP | TAP binding protein (tapasin) |
| TBX19 | T-box 19 |
| TCF4 | transcription factor 4 |
| TIMELESS | timeless circadian clock |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM209 | transmembrane protein 209 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRD | T cell receptor delta locus |
| USB1 | U6 snRNA biogenesis 1 |
| USP12 | ubiquitin specific peptidase 12 |
| USP36 | ubiquitin specific peptidase 36 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WDR59 | WD repeat domain 59 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YIPF2 | Yip1 domain family, member 2 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| AFF4 | AF4/FMR2 family, member 4 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C5 | complement component 5 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC85C | coiled-coil domain containing 85C |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLDND1 | claudin domain containing 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CSTA | cystatin A (stefin A) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EPPK1 | epiplakin 1 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FMO4 | flavin containing monooxygenase 4 |
| FOCAD | focadhesin |
| FRK | fyn-related Src family tyrosine kinase |
| GPR143 | G protein-coupled receptor 143 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HS1BP3 | HCLS1 binding protein 3 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| JADE3 | jade family PHD finger 3 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYRM9 | LYR motif containing 9 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MCOLN3 | mucolipin 3 |
| MED9 | mediator complex subunit 9 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MT1HL1 | metallothionein 1H-like 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NBEAL2 | neurobeachin-like 2 |
| NCK2 | NCK adaptor protein 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OXTR | oxytocin receptor |
| PGP | phosphoglycolate phosphatase |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| RBM41 | RNA binding motif protein 41 |
| RCOR3 | REST corepressor 3 |
| RNF121 | ring finger protein 121 |
| ROM1 | retinal outer segment membrane protein 1 |
| RWDD3 | RWD domain containing 3 |
| S100A4 | S100 calcium binding protein A4 |
| SAMHD1 | SAM domain and HD domain 1 |
| SAV1 | salvador family WW domain containing protein 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SPATA2L | spermatogenesis associated 2-like |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STRN4 | striatin, calmodulin binding protein 4 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAGLN | transgelin |
| TCTN1 | tectonic family member 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TOM1 | target of myb1 (chicken) |
| UBQLN4 | ubiquilin 4 |
| USP20 | ubiquitin specific peptidase 20 |
| WBP2 | WW domain binding protein 2 |
| XAB2 | XPA binding protein 2 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF211 | zinc finger protein 211 |
| ZNF468 | zinc finger protein 468 |
| ZNF552 | zinc finger protein 552 |