zomepirac-3454 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the zomepirac-3454 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
AMT aminomethyltransferase
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOM apolipoprotein M
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL4C ADP-ribosylation factor-like 4C
ATRX alpha thalassemia/mental retardation syndrome X-linked
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CARF calcium responsive transcription factor
CD83 CD83 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDK19 cyclin-dependent kinase 19
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCF1 cardiotrophin-like cytokine factor 1
COL5A1 collagen, type V, alpha 1
COMT catechol-O-methyltransferase
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNPEP aspartyl aminopeptidase
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EFNA3 ephrin-A3
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPHB2 EPH receptor B2
FLRT3 fibronectin leucine rich transmembrane protein 3
FSCN1 fascin actin-bundling protein 1
FST follistatin
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLRX3 glutaredoxin 3
GSK3A glycogen synthase kinase 3 alpha
GSTM1 glutathione S-transferase mu 1
GUK1 guanylate kinase 1
GYG2 glycogenin 2
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIST1H1D histone cluster 1, H1d
HIST1H3I histone cluster 1, H3i
HIST1H4F histone cluster 1, H4f
HIST2H2AA3 histone cluster 2, H2aa3
ICAM1 intercellular adhesion molecule 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM5D lysine (K)-specific demethylase 5D
KLHL20 kelch-like family member 20
KRT17 keratin 17, type I
LHX6 LIM homeobox 6
MAST3 microtubule associated serine/threonine kinase 3
MCF2L MCF.2 cell line derived transforming sequence-like
MCOLN1 mucolipin 1
MEFV Mediterranean fever
MOCS1 molybdenum cofactor synthesis 1
MZT2B mitotic spindle organizing protein 2B
NCAPH2 non-SMC condensin II complex, subunit H2
NMT1 N-myristoyltransferase 1
OAZ3 ornithine decarboxylase antizyme 3
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
RAB11B RAB11B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RECQL5 RecQ protein-like 5
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL1S RFPL1 antisense RNA 1
RGS10 regulator of G-protein signaling 10
SEC24D SEC24 family member D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH2B1 SH2B adaptor protein 1
SH2D3A SH2 domain containing 3A
SIDT2 SID1 transmembrane family, member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SMIM14 small integral membrane protein 14
SOS2 son of sevenless homolog 2 (Drosophila)
SPATA5L1 spermatogenesis associated 5-like 1
SSTR5 somatostatin receptor 5
STX7 syntaxin 7
SYT12 synaptotagmin XII
TAPBP TAP binding protein (tapasin)
TBX19 T-box 19
TCF4 transcription factor 4
TIMELESS timeless circadian clock
TJAP1 tight junction associated protein 1 (peripheral)
TMEM209 transmembrane protein 209
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAF2 TNF receptor-associated factor 2
TRD T cell receptor delta locus
USB1 U6 snRNA biogenesis 1
USP12 ubiquitin specific peptidase 12
USP36 ubiquitin specific peptidase 36
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR59 WD repeat domain 59
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YIPF2 Yip1 domain family, member 2
ZBTB44 zinc finger and BTB domain containing 44
ZCCHC11 zinc finger, CCHC domain containing 11
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
AFF4 AF4/FMR2 family, member 4
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ATAD5 ATPase family, AAA domain containing 5
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C16ORF45 chromosome 16 open reading frame 45
C1ORF159 chromosome 1 open reading frame 159
C2ORF44 chromosome 2 open reading frame 44
C5 complement component 5
CAPG capping protein (actin filament), gelsolin-like
CCDC85C coiled-coil domain containing 85C
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN2 chloride channel, voltage-sensitive 2
CLDND1 claudin domain containing 1
CRY2 cryptochrome circadian clock 2
CSTA cystatin A (stefin A)
CTNNBIP1 catenin, beta interacting protein 1
DSCAM Down syndrome cell adhesion molecule
ELOVL4 ELOVL fatty acid elongase 4
EML4 echinoderm microtubule associated protein like 4
EPPK1 epiplakin 1
ERO1L ERO1-like (S. cerevisiae)
FAM114A2 family with sequence similarity 114, member A2
FAN1 FANCD2/FANCI-associated nuclease 1
FEM1C fem-1 homolog c (C. elegans)
FMO4 flavin containing monooxygenase 4
FOCAD focadhesin
FRK fyn-related Src family tyrosine kinase
GPR143 G protein-coupled receptor 143
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HS1BP3 HCLS1 binding protein 3
ITPKC inositol-trisphosphate 3-kinase C
JADE3 jade family PHD finger 3
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT8P12 keratin 8 pseudogene 12
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LYPD1 LY6/PLAUR domain containing 1
LYRM9 LYR motif containing 9
MAN2C1 mannosidase, alpha, class 2C, member 1
MCOLN3 mucolipin 3
MED9 mediator complex subunit 9
MRPL52 mitochondrial ribosomal protein L52
MT1HL1 metallothionein 1H-like 1
MYL5 myosin, light chain 5, regulatory
NBEAL2 neurobeachin-like 2
NCK2 NCK adaptor protein 2
NIPAL2 NIPA-like domain containing 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OXTR oxytocin receptor
PGP phosphoglycolate phosphatase
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPT2 palmitoyl-protein thioesterase 2
RBM41 RNA binding motif protein 41
RCOR3 REST corepressor 3
RNF121 ring finger protein 121
ROM1 retinal outer segment membrane protein 1
RWDD3 RWD domain containing 3
S100A4 S100 calcium binding protein A4
SAMHD1 SAM domain and HD domain 1
SAV1 salvador family WW domain containing protein 1
SCAMP4 secretory carrier membrane protein 4
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH3BGR SH3 domain binding glutamate-rich protein
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC12A8 solute carrier family 12, member 8
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPATA2L spermatogenesis associated 2-like
SRD5A3 steroid 5 alpha-reductase 3
SREK1IP1 SREK1-interacting protein 1
STRN4 striatin, calmodulin binding protein 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAGLN transgelin
TCTN1 tectonic family member 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TOM1 target of myb1 (chicken)
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
WBP2 WW domain binding protein 2
XAB2 XPA binding protein 2
ZC3H3 zinc finger CCCH-type containing 3
ZNF211 zinc finger protein 211
ZNF468 zinc finger protein 468
ZNF552 zinc finger protein 552