zomepirac-6815 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the zomepirac-6815 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM22 ADAM metallopeptidase domain 22
ADAM8 ADAM metallopeptidase domain 8
ADRBK1 adrenergic, beta, receptor kinase 1
AFF2 AF4/FMR2 family, member 2
AJAP1 adherens junctions associated protein 1
ANGPTL2 angiopoietin-like 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARID5A AT rich interactive domain 5A (MRF1-like)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASB1 ankyrin repeat and SOCS box containing 1
BIN1 bridging integrator 1
BTF3P11 basic transcription factor 3 pseudogene 11
C1QTNF1 C1q and tumor necrosis factor related protein 1
C3ORF18 chromosome 3 open reading frame 18
CCAR2 cell cycle and apoptosis regulator 2
CCDC85B coiled-coil domain containing 85B
CCNK cyclin K
CFAP45 cilia and flagella associated protein 45
CLGN calmegin
CPNE7 copine VII
CTAGE5 CTAGE family, member 5
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMXL2 Dmx-like 2
DNAI2 dynein, axonemal, intermediate chain 2
EPX eosinophil peroxidase
EVA1B eva-1 homolog B (C. elegans)
FBXL7 F-box and leucine-rich repeat protein 7
FCMR Fc fragment of IgM receptor
FGFR3 fibroblast growth factor receptor 3
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GJB3 gap junction protein, beta 3, 31kDa
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR137 G protein-coupled receptor 137
HCRP1 hepatocellular carcinoma-related HCRP1
HIPK2 homeodomain interacting protein kinase 2
HIST1H2BN histone cluster 1, H2bn
HIST1H4C histone cluster 1, H4c
HLA-DOA major histocompatibility complex, class II, DO alpha
HR hair growth associated
HSPB6 heat shock protein, alpha-crystallin-related, B6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1RN interleukin 1 receptor antagonist
IL5RA interleukin 5 receptor, alpha
IL6R interleukin 6 receptor
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0125 KIAA0125
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC100131532 uncharacterized LOC100131532
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCAM melanoma cell adhesion molecule
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MERTK MER proto-oncogene, tyrosine kinase
MIER2 mesoderm induction early response 1, family member 2
MPZ myelin protein zero
NAAA N-acylethanolamine acid amidase
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFIB nuclear factor I/B
NPTX1 neuronal pentraxin I
OLFML2B olfactomedin-like 2B
ONECUT2 one cut homeobox 2
PDE4DIP phosphodiesterase 4D interacting protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PRB3 proline-rich protein BstNI subfamily 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PVRL3 poliovirus receptor-related 3
PWAR5 Prader Willi/Angelman region RNA 5
RAD52 RAD52 homolog (S. cerevisiae)
RAE1 ribonucleic acid export 1
RIMS3 regulating synaptic membrane exocytosis 3
RPL7 ribosomal protein L7
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SORBS1 sorbin and SH3 domain containing 1
SPRR1A small proline-rich protein 1A
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBKBP1 TBK1 binding protein 1
TIMELESS timeless circadian clock
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TM4SF1 transmembrane 4 L six family member 1
TPK1 thiamin pyrophosphokinase 1
TPMT thiopurine S-methyltransferase
USP22 ubiquitin specific peptidase 22
VPS13B vacuolar protein sorting 13 homolog B (yeast)
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADCY6 adenylate cyclase 6
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALS2CL ALS2 C-terminal like
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B9D2 B9 protein domain 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
C17ORF70 chromosome 17 open reading frame 70
C1ORF159 chromosome 1 open reading frame 159
C2ORF54 chromosome 2 open reading frame 54
C5AR2 complement component 5a receptor 2
CAMK1D calcium/calmodulin-dependent protein kinase ID
CDK20 cyclin-dependent kinase 20
CGA glycoprotein hormones, alpha polypeptide
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLEC16A C-type lectin domain family 16, member A
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
DBF4B DBF4 zinc finger B
DDIT3 DNA-damage-inducible transcript 3
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DEAF1 DEAF1 transcription factor
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FAM169A family with sequence similarity 169, member A
FBXO31 F-box protein 31
FSD1 fibronectin type III and SPRY domain containing 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLS2 glutaminase 2 (liver, mitochondrial)
GMPPA GDP-mannose pyrophosphorylase A
GPR27 G protein-coupled receptor 27
GRB7 growth factor receptor-bound protein 7
HDAC4 histone deacetylase 4
HLA-J major histocompatibility complex, class I, J (pseudogene)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IQCG IQ motif containing G
IQSEC2 IQ motif and Sec7 domain 2
KIAA0319L KIAA0319-like
KLK5 kallikrein-related peptidase 5
KREMEN2 kringle containing transmembrane protein 2
LY6D lymphocyte antigen 6 complex, locus D
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFAP2 microfibrillar-associated protein 2
PCBP3 poly(rC) binding protein 3
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PQLC1 PQ loop repeat containing 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCRL pyrroline-5-carboxylate reductase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RPL13P5 ribosomal protein L13 pseudogene 5
SALL2 spalt-like transcription factor 2
SAYSD1 SAYSVFN motif domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCPEP1 serine carboxypeptidase 1
SCRN3 secernin 3
SFMBT1 Scm-like with four mbt domains 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMIM14 small integral membrane protein 14
SPAG4 sperm associated antigen 4
TCTA T-cell leukemia translocation altered
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR5 toll-like receptor 5
TM6SF1 transmembrane 6 superfamily member 1
TMEM121 transmembrane protein 121
TMEM212 transmembrane protein 212
TMEM57 transmembrane protein 57
TPRA1 transmembrane protein, adipocyte asscociated 1
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
UPK3B uroplakin 3B
UPP1 uridine phosphorylase 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF492 zinc finger protein 492
ZNHIT2 zinc finger, HIT-type containing 2