zoxazolamine-1270 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the zoxazolamine-1270 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADGRE1 adhesion G protein-coupled receptor E1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP13A2 ATPase type 13A2
ATXN7L3B ataxin 7-like 3B
AXIN1 axin 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNC2 basonuclin 2
C7ORF43 chromosome 7 open reading frame 43
CDC14A cell division cycle 14A
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDR2L cerebellar degeneration-related protein 2-like
CES3 carboxylesterase 3
CHMP6 charged multivesicular body protein 6
CLCN7 chloride channel, voltage-sensitive 7
CLSPN claspin
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNTLN centlein, centrosomal protein
COL9A2 collagen, type IX, alpha 2
CRY2 cryptochrome circadian clock 2
DLG4 discs, large homolog 4 (Drosophila)
E2F1 E2F transcription factor 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ESR1 estrogen receptor 1
EXOSC1 exosome component 1
FBXL18 F-box and leucine-rich repeat protein 18
FST follistatin
GDF11 growth differentiation factor 11
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLCE glucuronic acid epimerase
HDAC7 histone deacetylase 7
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HLA-DMA major histocompatibility complex, class II, DM alpha
HSF1 heat shock transcription factor 1
IFFO1 intermediate filament family orphan 1
INF2 inverted formin, FH2 and WH2 domain containing
ITSN1 intersectin 1 (SH3 domain protein)
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KHSRP KH-type splicing regulatory protein
LDB1 LIM domain binding 1
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP4 microtubule-associated protein 4
MINK1 misshapen-like kinase 1
MTRF1L mitochondrial translational release factor 1-like
MYO1E myosin IE
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPEPL1 aminopeptidase-like 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OASL 2'-5'-oligoadenylate synthetase-like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVGP1 oviductal glycoprotein 1, 120kDa
PDCD2 programmed cell death 2
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PIR pirin (iron-binding nuclear protein)
PLCB2 phospholipase C, beta 2
PML promyelocytic leukemia
POU6F1 POU class 6 homeobox 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PVT1 Pvt1 oncogene (non-protein coding)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RTN2 reticulon 2
RUNX1 runt-related transcription factor 1
SFXN3 sideroflexin 3
SGSM2 small G protein signaling modulator 2
SLC16A4 solute carrier family 16, member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SPATA2 spermatogenesis associated 2
SPATA2L spermatogenesis associated 2-like
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPRY4 sprouty homolog 4 (Drosophila)
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SYNGR1 synaptogyrin 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCTN1 tectonic family member 1
THOC5 THO complex 5
TMEM180 transmembrane protein 180
TMEM53 transmembrane protein 53
TMOD1 tropomodulin 1
TRMT61A tRNA methyltransferase 61A
TTC38 tetratricopeptide repeat domain 38
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
WAS Wiskott-Aldrich syndrome
WRAP53 WD repeat containing, antisense to TP53
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZNF34 zinc finger protein 34
ZNF574 zinc finger protein 574
ZNF721 zinc finger protein 721
ZNF76 zinc finger protein 76
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACVR2B activin A receptor, type IIB
ADTRP androgen-dependent TFPI-regulating protein
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANAPC2 anaphase promoting complex subunit 2
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARMC6 armadillo repeat containing 6
ASTE1 asteroid homolog 1 (Drosophila)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHCC1 BAH domain and coiled-coil containing 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C10ORF88 chromosome 10 open reading frame 88
C17ORF75 chromosome 17 open reading frame 75
C22ORF46 chromosome 22 open reading frame 46
C3 complement component 3
C5ORF45 chromosome 5 open reading frame 45
CEP170B centrosomal protein 170B
CPTP ceramide-1-phosphate transfer protein
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFCAB2 EF-hand calcium binding domain 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EXOC5 exocyst complex component 5
FEM1C fem-1 homolog c (C. elegans)
FHIT fragile histidine triad
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GJA1 gap junction protein, alpha 1, 43kDa
GLTP glycolipid transfer protein
GPALPP1 GPALPP motifs containing 1
GPHN gephyrin
GRWD1 glutamate-rich WD repeat containing 1
GTPBP3 GTP binding protein 3 (mitochondrial)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HIST1H2BF histone cluster 1, H2bf
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMPAD1 inositol monophosphatase domain containing 1
IRF9 interferon regulatory factor 9
KCTD15 potassium channel tetramerization domain containing 15
KLHL12 kelch-like family member 12
LMAN1 lectin, mannose-binding, 1
LPAR4 lysophosphatidic acid receptor 4
LRRK1 leucine-rich repeat kinase 1
MBIP MAP3K12 binding inhibitory protein 1
MICALL2 MICAL-like 2
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MT1HL1 metallothionein 1H-like 1
MTRF1 mitochondrial translational release factor 1
MX2 MX dynamin-like GTPase 2
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NRGN neurogranin (protein kinase C substrate, RC3)
NT5C 5', 3'-nucleotidase, cytosolic
NT5M 5',3'-nucleotidase, mitochondrial
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PARPBP PARP1 binding protein
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PSAT1 phosphoserine aminotransferase 1
RFX7 regulatory factor X, 7
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF122 ring finger protein 122
RNF31 ring finger protein 31
RPP38 ribonuclease P/MRP 38kDa subunit
SCD5 stearoyl-CoA desaturase 5
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A40 solute carrier family 25, member 40
SLC35E3 solute carrier family 35, member E3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
TIGAR TP53 induced glycolysis regulatory phosphatase
TLR4 toll-like receptor 4
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM230 transmembrane protein 230
TMEM50B transmembrane protein 50B
TRAPPC13 trafficking protein particle complex 13
TTC4 tetratricopeptide repeat domain 4
TUBA3D tubulin, alpha 3d
USB1 U6 snRNA biogenesis 1
VNN2 vanin 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XKR8 XK, Kell blood group complex subunit-related family, member 8
YIPF5 Yip1 domain family, member 5
ZBED8 zinc finger, BED-type containing 8
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF250 zinc finger protein 250
ZNF350 zinc finger protein 350
ZNF665 zinc finger protein 665