zoxazolamine-5390 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the zoxazolamine-5390 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADM adrenomedullin
AMPD3 adenosine monophosphate deaminase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C11ORF63 chromosome 11 open reading frame 63
C14ORF79 chromosome 14 open reading frame 79
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC40 coiled-coil domain containing 40
CCL27 chemokine (C-C motif) ligand 27
CD70 CD70 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHN2 chimerin 2
CHRD chordin
CLCF1 cardiotrophin-like cytokine factor 1
CLCN7 chloride channel, voltage-sensitive 7
COL11A2 collagen, type XI, alpha 2
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
COPE coatomer protein complex, subunit epsilon
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DESI2 desumoylating isopeptidase 2
DFNA5 deafness, autosomal dominant 5
DICER1 dicer 1, ribonuclease type III
DOCK5 dedicator of cytokinesis 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXO41 F-box protein 41
FCAR Fc fragment of IgA receptor
FETUB fetuin B
FGF12 fibroblast growth factor 12
FRMD4A FERM domain containing 4A
FUS FUS RNA binding protein
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPC1 glypican 1
GPR137 G protein-coupled receptor 137
GRM3 glutamate receptor, metabotropic 3
GSTP1 glutathione S-transferase pi 1
GTDC1 glycosyltransferase-like domain containing 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC7 histone deacetylase 7
HIST1H3I histone cluster 1, H3i
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA2 homeobox A2
IDS iduronate 2-sulfatase
IFNA16 interferon, alpha 16
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IL11RA interleukin 11 receptor, alpha
ITGB4 integrin, beta 4
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0355 KIAA0355
KRT8 keratin 8, type II
LIN7B lin-7 homolog B (C. elegans)
LRP12 low density lipoprotein receptor-related protein 12
MAST3 microtubule associated serine/threonine kinase 3
MED16 mediator complex subunit 16
MKL1 megakaryoblastic leukemia (translocation) 1
MLANA melan-A
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBPC3 myosin binding protein C, cardiac
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMT1 N-myristoyltransferase 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OGFR opioid growth factor receptor
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCDH1 protocadherin 1
PCLO piccolo presynaptic cytomatrix protein
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POU2F2 POU class 2 homeobox 2
PRKCE protein kinase C, epsilon
PRKCI protein kinase C, iota
PTN pleiotrophin
RAB6A RAB6A, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGS7 regulator of G-protein signaling 7
SCAND2P SCAN domain containing 2 pseudogene
SFTPB surfactant protein B
SH2D3A SH2 domain containing 3A
SKI SKI proto-oncogene
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRCAP Snf2-related CREBBP activator protein
SULT4A1 sulfotransferase family 4A, member 1
TBC1D2B TBC1 domain family, member 2B
TCEAL2 transcription elongation factor A (SII)-like 2
TCF25 transcription factor 25 (basic helix-loop-helix)
TRBC1 T cell receptor beta constant 1
TRIM29 tripartite motif containing 29
VPRBP Vpr (HIV-1) binding protein
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZNF197 zinc finger protein 197

decreased expression

Symbol Name
ACP2 acid phosphatase 2, lysosomal
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKRD36 ankyrin repeat domain 36
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
BHLHE41 basic helix-loop-helix family, member e41
BLNK B-cell linker
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF80 chromosome 11 open reading frame 80
C7ORF43 chromosome 7 open reading frame 43
C9ORF9 chromosome 9 open reading frame 9
CA5BP1 carbonic anhydrase VB pseudogene 1
CBX4 chromobox homolog 4
CCNJ cyclin J
CD79B CD79b molecule, immunoglobulin-associated beta
CD8A CD8a molecule
CDK3 cyclin-dependent kinase 3
CES3 carboxylesterase 3
CNGB3 cyclic nucleotide gated channel beta 3
CRY2 cryptochrome circadian clock 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUEDC1 CUE domain containing 1
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGAT1 diacylglycerol O-acyltransferase 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAL4 dynein, axonemal, light chain 4
DUSP2 dual specificity phosphatase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131A family with sequence similarity 131, member A
FAM212B family with sequence similarity 212, member B
FBXL2 F-box and leucine-rich repeat protein 2
FKBP10 FK506 binding protein 10, 65 kDa
FRK fyn-related Src family tyrosine kinase
GJA9 gap junction protein, alpha 9, 59kDa
GPR143 G protein-coupled receptor 143
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HLA-DMA major histocompatibility complex, class II, DM alpha
HP1BP3 heterochromatin protein 1, binding protein 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSPA1L heat shock 70kDa protein 1-like
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IL4R interleukin 4 receptor
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0125 KIAA0125
KLK5 kallikrein-related peptidase 5
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
LINS lines homolog (Drosophila)
LOC390998 ribosomal protein L10 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
LZTR1 leucine-zipper-like transcription regulator 1
METTL16 methyltransferase like 16
MTERF4 mitochondrial transcription termination factor 4
NAT6 N-acetyltransferase 6 (GCN5-related)
NEK11 NIMA-related kinase 11
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
ORAI3 ORAI calcium release-activated calcium modulator 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHA6 protocadherin alpha 6
PCDHA9 protocadherin alpha 9
PDE12 phosphodiesterase 12
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMCH pro-melanin-concentrating hormone
RAB3A RAB3A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASA2 RAS p21 protein activator 2
SETD8 SET domain containing (lysine methyltransferase) 8
SIX1 SIX homeobox 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPAG4 sperm associated antigen 4
ST5 suppression of tumorigenicity 5
STARD13 StAR-related lipid transfer (START) domain containing 13
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEP1 telomerase-associated protein 1
TFPI2 tissue factor pathway inhibitor 2
THRAP3 thyroid hormone receptor associated protein 3
TLR5 toll-like receptor 5
TM6SF1 transmembrane 6 superfamily member 1
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRABD TraB domain containing
TUBA3C tubulin, alpha 3c
UBXN6 UBX domain protein 6
VGF VGF nerve growth factor inducible
VWA1 von Willebrand factor A domain containing 1
WDR62 WD repeat domain 62
XK X-linked Kx blood group
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF350 zinc finger protein 350