zuclopenthixol-2936 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the zuclopenthixol-2936 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRB1 adhesion G protein-coupled receptor B1
AMPD3 adenosine monophosphate deaminase 3
AMPH amphiphysin
ANKH ANKH inorganic pyrophosphate transport regulator
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP1 aquaporin 1 (Colton blood group)
BEGAIN brain-enriched guanylate kinase-associated
BIN1 bridging integrator 1
CD84 CD84 molecule
CDK20 cyclin-dependent kinase 20
CFAP45 cilia and flagella associated protein 45
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLCN4 chloride channel, voltage-sensitive 4
CLEC4A C-type lectin domain family 4, member A
CLEC4E C-type lectin domain family 4, member E
CLPS colipase, pancreatic
CLTA clathrin, light chain A
COL9A3 collagen, type IX, alpha 3
CTNS cystinosin, lysosomal cystine transporter
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DUSP4 dual specificity phosphatase 4
ELSPBP1 epididymal sperm binding protein 1
EML2 echinoderm microtubule associated protein like 2
ESR1 estrogen receptor 1
FCAR Fc fragment of IgA receptor
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FRMD8 FERM domain containing 8
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLI3 GLI family zinc finger 3
HDAC7 histone deacetylase 7
HEG1 heart development protein with EGF-like domains 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL12RB1 interleukin 12 receptor, beta 1
INPP5J inositol polyphosphate-5-phosphatase J
KIAA0319L KIAA0319-like
KRT33A keratin 33A, type I
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAGEA3 melanoma antigen family A3
MAP3K7CL MAP3K7 C-terminal like
MAPK13 mitogen-activated protein kinase 13
MECP2 methyl CpG binding protein 2
MFSD6 major facilitator superfamily domain containing 6
MUC1 mucin 1, cell surface associated
MXD1 MAX dimerization protein 1
MYBPC3 myosin binding protein C, cardiac
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NNAT neuronatin
NRF1 nuclear respiratory factor 1
PAX5 paired box 5
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF1 PHD finger protein 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PODNL1 podocan-like 1
POFUT1 protein O-fucosyltransferase 1
PORCN porcupine homolog (Drosophila)
PRKCA protein kinase C, alpha
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PVR poliovirus receptor
RPL23AP32 ribosomal protein L23a pseudogene 32
RUSC2 RUN and SH3 domain containing 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRT3 sirtuin 3
SIRT5 sirtuin 5
SIX2 SIX homeobox 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC39A9 solute carrier family 39, member 9
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SNW1 SNW domain containing 1
SOGA1 suppressor of glucose, autophagy associated 1
SPATA1 spermatogenesis associated 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST7L suppression of tumorigenicity 7 like
TAOK2 TAO kinase 2
TAPBP TAP binding protein (tapasin)
THAP9 THAP domain containing 9
TMEM19 transmembrane protein 19
TMEM212 transmembrane protein 212
TMOD1 tropomodulin 1
TPMT thiopurine S-methyltransferase
TRAF2 TNF receptor-associated factor 2
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA3C tubulin, alpha 3c
ULK4 unc-51 like kinase 4
XYLB xylulokinase homolog (H. influenzae)
ZER1 zyg-11 related, cell cycle regulator
ZNF862 zinc finger protein 862
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ADGRE5 adhesion G protein-coupled receptor E5
AEN apoptosis enhancing nuclease
ANAPC2 anaphase promoting complex subunit 2
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARF5 ADP-ribosylation factor 5
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BIRC3 baculoviral IAP repeat containing 3
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CAPN1 calpain 1, (mu/I) large subunit
CBS cystathionine-beta-synthase
CCDC176 coiled-coil domain containing 176
CCNE1 cyclin E1
CD180 CD180 molecule
CD320 CD320 molecule
CEL carboxyl ester lipase
CHMP1A charged multivesicular body protein 1A
CHMP6 charged multivesicular body protein 6
CRY2 cryptochrome circadian clock 2
CRYBG3 beta-gamma crystallin domain containing 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DCAF17 DDB1 and CUL4 associated factor 17
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DGAT1 diacylglycerol O-acyltransferase 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM204A family with sequence similarity 204, member A
FAM50B family with sequence similarity 50, member B
FANCF Fanconi anemia, complementation group F
FBRS fibrosin
FGL2 fibrinogen-like 2
FJX1 four jointed box 1 (Drosophila)
GEM GTP binding protein overexpressed in skeletal muscle
GPR63 G protein-coupled receptor 63
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4E histone cluster 1, H4e
HYAL2 hyaluronoglucosaminidase 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL18 interleukin 18
INF2 inverted formin, FH2 and WH2 domain containing
KDM7A lysine (K)-specific demethylase 7A
KIF24 kinesin family member 24
LAX1 lymphocyte transmembrane adaptor 1
LNPEP leucyl/cystinyl aminopeptidase
LPAR6 lysophosphatidic acid receptor 6
LRRK1 leucine-rich repeat kinase 1
LXN latexin
MCPH1 microcephalin 1
METTL16 methyltransferase like 16
MON1B MON1 secretory trafficking family member B
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NTSR1 neurotensin receptor 1 (high affinity)
NUBPL nucleotide binding protein-like
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI2 peptidyl arginine deiminase, type II
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POLM polymerase (DNA directed), mu
POMT1 protein-O-mannosyltransferase 1
POR P450 (cytochrome) oxidoreductase
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
QSER1 glutamine and serine rich 1
RAD54L RAD54-like (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPGRIP1L RPGRIP1-like
SCAMP4 secretory carrier membrane protein 4
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SNX15 sorting nexin 15
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STEAP3 STEAP family member 3, metalloreductase
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TERT telomerase reverse transcriptase
THBS3 thrombospondin 3
THOP1 thimet oligopeptidase 1
TLN1 talin 1
TRABD TraB domain containing
TRAPPC2L trafficking protein particle complex 2-like
TTC4 tetratricopeptide repeat domain 4
TUBB2A tubulin, beta 2A class IIa
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2O ubiquitin-conjugating enzyme E2O
USP19 ubiquitin specific peptidase 19
VCPKMT valosin containing protein lysine (K) methyltransferase
YY2 YY2 transcription factor
ZDHHC18 zinc finger, DHHC-type containing 18
ZMAT3 zinc finger, matrin-type 3
ZNF250 zinc finger protein 250
ZNF580 zinc finger protein 580