zuclopenthixol-4261 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the zuclopenthixol-4261 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADAM22 ADAM metallopeptidase domain 22
AGXT alanine-glyoxylate aminotransferase
ANKRD53 ankyrin repeat domain 53
ATN1 atrophin 1
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
CCL5 chemokine (C-C motif) ligand 5
CD6 CD6 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLEC4A C-type lectin domain family 4, member A
CLIC2 chloride intracellular channel 2
CLMN calmin (calponin-like, transmembrane)
COL2A1 collagen, type II, alpha 1
DCC DCC netrin 1 receptor
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DMWD dystrophia myotonica, WD repeat containing
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DSC1 desmocollin 1
EFS embryonal Fyn-associated substrate
EPHA7 EPH receptor A7
ESR1 estrogen receptor 1
FAM149A family with sequence similarity 149, member A
FRMD8 FERM domain containing 8
GLRA2 glycine receptor, alpha 2
HRG histidine-rich glycoprotein
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IDS iduronate 2-sulfatase
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGLJ3 immunoglobulin lambda joining 3
INS insulin
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLK3 kallikrein-related peptidase 3
KRTAP1-3 keratin associated protein 1-3
KYNU kynureninase
LARGE like-glycosyltransferase
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LINC00474 long intergenic non-protein coding RNA 474
LST1 leukocyte specific transcript 1
LY6G6D lymphocyte antigen 6 complex, locus G6D
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MCF2L MCF.2 cell line derived transforming sequence-like
MFAP3L microfibrillar-associated protein 3-like
MNMIP1 manchette microtubule inner protein 1
MUC4 mucin 4, cell surface associated
MYCNOS MYCN opposite strand
MYH13 myosin, heavy chain 13, skeletal muscle
MYOZ1 myozenin 1
NCR1 natural cytotoxicity triggering receptor 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NHLH2 nescient helix loop helix 2
NLRP3 NLR family, pyrin domain containing 3
NME8 NME/NM23 family member 8
NMUR1 neuromedin U receptor 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NUMA1 nuclear mitotic apparatus protein 1
NUP88 nucleoporin 88kDa
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDHB17P protocadherin beta 17 pseudogene
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PHF7 PHD finger protein 7
PRDM12 PR domain containing 12
PRDM14 PR domain containing 14
PRDM2 PR domain containing 2, with ZNF domain
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYY2 peptide YY, 2 (pseudogene)
RASAL1 RAS protein activator like 1 (GAP1 like)
RCE1 Ras converting CAAX endopeptidase 1
REEP1 receptor accessory protein 1
RETN resistin
RHO rhodopsin
RS1 retinoschisin 1
SI sucrase-isomaltase (alpha-glucosidase)
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLFN12 schlafen family member 12
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNED1 sushi, nidogen and EGF-like domains 1
SOX14 SRY (sex determining region Y)-box 14
SVIL supervillin
TBC1D2 TBC1 domain family, member 2
TLR8 toll-like receptor 8
TMPRSS4 transmembrane protease, serine 4
TRAF3IP3 TRAF3 interacting protein 3
TRO trophinin
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TTLL5 tubulin tyrosine ligase-like family member 5
XAF1 XIAP associated factor 1

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADCY6 adenylate cyclase 6
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AEN apoptosis enhancing nuclease
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANOS1 anosmin 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
BGLAP bone gamma-carboxyglutamate (gla) protein
BNC1 basonuclin 1
BOLA1 bolA family member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
C16ORF59 chromosome 16 open reading frame 59
C5ORF42 chromosome 5 open reading frame 42
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCP110 centriolar coiled coil protein 110kDa
CHMP6 charged multivesicular body protein 6
CHRM3 cholinergic receptor, muscarinic 3
CLDN11 claudin 11
CLDN15 claudin 15
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSO cathepsin O
CUZD1 CUB and zona pellucida-like domains 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EFNA3 ephrin-A3
EML4 echinoderm microtubule associated protein like 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM50B family with sequence similarity 50, member B
FAM69A family with sequence similarity 69, member A
FAT4 FAT atypical cadherin 4
FBXL7 F-box and leucine-rich repeat protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GDAP1 ganglioside induced differentiation associated protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPATCH2L G patch domain containing 2-like
GRAMD1C GRAM domain containing 1C
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H3C histone cluster 1, H3c
HOOK1 hook microtubule-tethering protein 1
HOXA1 homeobox A1
HOXC5 homeobox C5
IFNA17 interferon, alpha 17
IFT54 intraflagellar transport 54
IL36RN interleukin 36 receptor antagonist
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0753 KIAA0753
KIF3A kinesin family member 3A
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC730101 uncharacterized LOC730101
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OSR2 odd-skipped related transciption factor 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PMCH pro-melanin-concentrating hormone
POM121 POM121 transmembrane nucleoporin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRPH peripherin
PRR4 proline rich 4 (lacrimal)
PTK7 protein tyrosine kinase 7 (inactive)
RNF126P1 ring finger protein 126 pseudogene 1
SETD8 SET domain containing (lysine methyltransferase) 8
SHROOM2 shroom family member 2
SLITRK5 SLIT and NTRK-like family, member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPRYD7 SPRY domain containing 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAGLN3 transgelin 3
TEX40 testis expressed 40
THBS3 thrombospondin 3
TLR2 toll-like receptor 2
TMEM186 transmembrane protein 186
TMEM242 transmembrane protein 242
TRDMT1 tRNA aspartic acid methyltransferase 1
TSPAN8 tetraspanin 8
TXLNG taxilin gamma
VGLL3 vestigial-like family member 3
YOD1 YOD1 deubiquitinase
ZNF10 zinc finger protein 10
ZNF492 zinc finger protein 492
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZNF778 zinc finger protein 778